Biophysical and Structural Characterization of Novel RAS-Binding Domains (RBDs) of PI3Kα and PI3Kγ.

Autor: Martinez NG; Department of Biochemistry & Biophysics, University of North Carolina at Chapel Hill, United States., Thieker DF; Department of Biochemistry & Biophysics, University of North Carolina at Chapel Hill, United States; Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, United States., Carey LM; Department of Biochemistry & Biophysics, University of North Carolina at Chapel Hill, United States; Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, United States., Rasquinha JA; Department of Biochemistry & Biophysics, University of North Carolina at Chapel Hill, United States., Kistler SK; Department of Biochemistry & Biophysics, University of North Carolina at Chapel Hill, United States., Kuhlman BA; Department of Biochemistry & Biophysics, University of North Carolina at Chapel Hill, United States; Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, United States., Campbell SL; Department of Biochemistry & Biophysics, University of North Carolina at Chapel Hill, United States; Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, United States. Electronic address: campbesl@med.unc.edu.

Publikováno v: Journal of molecular biology [J Mol Biol] 2021 Apr 16; Vol. 433 (8), pp. 166838. Date of Electronic Publication: 2021 Feb 01.