Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Kishorekumar Kanagavel"'
Autor:
Michael A. Schmidt, Chunshan Xie, Naidu S. Chowdari, Ankita G. Niyogi, David R. Langley, Heng Cheng, Gregory D. Vite, Sivakrishna Guturi, Rajappa Vaidyanathan, Sanjeev Gangwar, Ivar M. McDonald, Kishorekumar Kanagavel, Yichen Tan, Prasanna Sivaprakasam, Souvik Rakshit, Chin Pan, Umamaheswararao Kanusu, Martin D. Eastgate, Madhura Deshpande, Somprabha Sidhar, Bin Zheng, Christiana I. Iwuagwu, Michael R. Luzung, Ganapathy Sarma, Kevin M. Peese, Thirumalai Lakshminarasimhan, Patrick G. Holder, Pina M. Cardarelli, Patricia Cho, Srikanth Kotapati, Chetana Rao
Publikováno v:
ACS Med Chem Lett
[Image: see text] A new series with the tetrahydroisoquinoline-fused benzodiazepine (TBD) ring system combined with the surrogates of (1-methyl-1H-pyrrol-3-yl)benzene (“MPB”) payloads were designed and executed for conjugation with a monoclonal a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ebc8e44bdde09da681c8a7885776a0f
https://doi.org/10.1021/acsmedchemlett.0c00578
https://doi.org/10.1021/acsmedchemlett.0c00578
Autor:
Sundaramurthy Rangaswamy, Kathryn Camacho, Rajappa Vaidyanathan, Siva Krishna Guturi, Martin D. Eastgate, Durgarao Bandaru, Rajaram Ayothiraman, Kishorekumar Kanagavel, Cuniere Nicolas, Serge Zaretsky, Mohamed Jaleel, Thirumalai Lakshminarasimhan, Aravind S. Gangu
Publikováno v:
Organic Process Research & Development. 24:207-215
Two approaches to a 1-aryl-4-trifluoromethyltriazole are described. Initially, a late-stage trifluoromethylation of the corresponding 1-aryl-4-iodotriazole using methyl fluorosulfonyldifluoroacetat...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::746dc3518850e9887c08700e4cffb679
https://doi.org/10.1021/acs.oprd.9b00492
https://doi.org/10.1021/acs.oprd.9b00492
Autor:
Kishorekumar Kanagavel, Michael A. Schmidt, Bin Zheng, Sivakrishna Guturi, Rajappa Vaidyanathan, Souvik Rakshit, Michael R. Luzung, Somprabha Sidar, Thirumalai Lakshminarasimhan, Ankita G. Niyogi, Umamaheswara Rao Kanusu, Martin D. Eastgate
Publikováno v:
Organic Process Research & Development. 22:391-398
We report herein an improved synthesis of 6-nitrovanillin, an important building block used in pharmaceuticals and agrochemicals. The key step in this sequence is the nitration of O-Bn vanillin, which was carried out using fuming HNO3. Sulfolane emer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::94b191cedc7fee3fb6653c38e126a2b3
https://doi.org/10.1021/acs.oprd.8b00020
https://doi.org/10.1021/acs.oprd.8b00020