Zobrazeno 1 - 10
of 71
pro vyhledávání: '"Kishore V. L. Parsa"'
Autor:
Rahul Sharma, Sujay K. Maity, Partha Chakrabarti, Madhumohan R. Katika, Satyamoorthy Kapettu, Kishore V. L. Parsa, Parimal Misra
Publikováno v:
International Journal of Molecular Sciences; Volume 24; Issue 9; Pages: 8084
Pancreatic beta cell function is an important component of glucose homeostasis. Here, we investigated the function of PIMT (PRIP-interacting protein with methyl transferase domain), a transcriptional co-activator binding protein, in the pancreatic be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04f7e5dbee8a706cf893d0f8029d4518
Autor:
Jetta Sandeep Kumar, B. Thirupataiah, Jayesh Mudgal, Gangireddy Sujeevan Reddy, Guntipally Mounika, Kazi Amirul Hossain, Marina Rajadurai, Jessy Elizabeth Mathew, Gautham G. Shenoy, Kishore V. L. Parsa, Manojit Pal
Publikováno v:
Chemical Communications. 57:10091-10094
A Pd-catalysed regioselective synthesis of 4,5-disubstituted 7-membered N/O-heterocycles was achieved via the 7-endo-dig cyclization followed by C–C bond formation of 2-(1-alkynyl)phenylacetamide. The ligand/additive free cascade reaction proceeded
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c47dc332e07b7b9ffdfb20caeab9f3a
https://doi.org/10.1039/d1cc04140a
https://doi.org/10.1039/d1cc04140a
Autor:
B, Thirupataiah, Guntipally, Mounika, Gangireddy, Sujeevan Reddy, Jetta, Sandeep Kumar, Ravikumar, Kapavarapu, Raghavender, Medishetti, Jayesh, Mudgal, Jessy E, Mathew, Gautham G, Shenoy, C, Mallikarjuna Rao, Kiranam, Chatti, Kishore, V L Parsa, Manojit, Pal
Publikováno v:
Bioorganic chemistry. 115
In spite of possessing a wide range of pharmacological properties the anti-inflammatory activities of isoquinolin-1(2H)-ones were rarely known or explored earlier. PDE4 inhibitors on the other hand in addition to their usefulness in treating inflamma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::fab6367eae7262d990036a230948cf98
https://pubmed.ncbi.nlm.nih.gov/34426160
https://pubmed.ncbi.nlm.nih.gov/34426160
Autor:
Kishore V. L. Parsa, Jayesh Mudgal, E.V.V. Shivaji Ramarao, Jetta Sandeep Kumar, Ramudu Bankala, Hari Maduri Doss, Mahaboobkhan Rasool, Manojit Pal, Rajnikanth Sunke, Pushkar Kulkarni, B. Thirupataiah, Ravikumar Kapavarapu, Gautham G. Shenoy, Raghavender Medishetti, Jessy Elizabeth Mathew
Publikováno v:
European Journal of Medicinal Chemistry. 174:198-215
A new class of PDE4 inhibitors were designed and synthesized via the InCl3 mediated heteroarylation of indoles and their further derivatization through the Pd(II)-catalyzed C H activation strategy. This effort allowed us to discover a series of 2-(1H
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5aec68d5d4d21d2e7d1057a76f345800
https://doi.org/10.1016/j.ejmech.2019.04.020
https://doi.org/10.1016/j.ejmech.2019.04.020
Autor:
B, Thirupataiah, Guntipally, Mounika, Gangireddy Sujeevan, Reddy, Jetta Sandeep, Kumar, Kazi Amirul, Hossain, Raghavender, Medishetti, Snigdha, Samarpita, Mahaboobkhan, Rasool, Jayesh, Mudgal, Jessy E, Mathew, Gautham G, Shenoy, C Mallikarjuna, Rao, Kiranam, Chatti, Kishore V L, Parsa, Manojit, Pal
Publikováno v:
European journal of medicinal chemistry. 221
While anti-inflammatory properties of isocoumarins are known their PDE4 inhibitory potential was not explored previously. In our effort the non-PDE4 inhibitor isocoumarins were transformed into the promising inhibitors via introducing an aminosulfony
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::65e763f432a55d48daf040d57ef951bd
https://pubmed.ncbi.nlm.nih.gov/33992926
https://pubmed.ncbi.nlm.nih.gov/33992926
Autor:
Bandish Kapadia, Navin Viswakarma, Kishore V L Parsa, Vasundhara Kain, Soma Behera, Sashidhara Kaimal Suraj, Phanithi Prakash Babu, Anand Kar, Sunanda Panda, Yi-jun Zhu, Yuzhi Jia, Bayar Thimmapaya, Janardan K Reddy, Parimal Misra
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e83787 (2013)
PRIP-Interacting protein with methyl transferase domain (PIMT) serves as a molecular bridge between CREB-binding protein (CBP)/ E1A binding protein p300 (Ep300) -anchored histone acetyl transferase and the Mediator complex sub-unit1 (Med1) and modula
Externí odkaz:
https://doaj.org/article/ac7fd69b17ac4234806af189b2eaa0c3
Autor:
Murugesan V S Rajaram, Jonathan P Butchar, Kishore V L Parsa, Thomas J Cremer, Amal Amer, Larry S Schlesinger, Susheela Tridandapani
Publikováno v:
PLoS ONE, Vol 4, Iss 11, p e7919 (2009)
Francisella tularensis infects macrophages and escapes phago-lysosomal fusion to replicate within the host cytosol, resulting in host cell apoptosis. Here we show that the Fas-mediated death pathway is activated in infected cells and correlates with
Externí odkaz:
https://doaj.org/article/d7968bac684a46f1b4e8c28013c8d14f
Autor:
Gautham G. Shenoy, Kazi Amirul Hossain, C. Mallikarjuna Rao, Gangireddy Sujeevan Reddy, Raghavender Medishetti, Mahaboobkhan Rasool, Kishore V. L. Parsa, Manojit Pal, Guntipally Mounika, Jetta Sandeep Kumar, Jayesh Mudgal, Kiranam Chatti, B. Thirupataiah, Snigdha Samarpita, Jessy Elizabeth Mathew
Publikováno v:
European Journal of Medicinal Chemistry. 221:113514
While anti-inflammatory properties of isocoumarins are known their PDE4 inhibitory potential was not explored previously. In our effort the non-PDE4 inhibitor isocoumarins were transformed into the promising inhibitors via introducing an aminosulfony
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d6eb1ed69873e7de4a41198910caf90b
https://doi.org/10.1016/j.ejmech.2021.113514
https://doi.org/10.1016/j.ejmech.2021.113514
Autor:
Raghavender Medishetti, Jayesh Mudgal, B. Thirupataiah, Ravikumar Kapavarapu, Kishore V. L. Parsa, Jetta Sandeep Kumar, Guntipally Mounika, Gautham G. Shenoy, Manojit Pal, Kiranam Chatti, Gangireddy Sujeevan Reddy, Jessy Elizabeth Mathew, C. Mallikarjuna Rao
Publikováno v:
Bioorganic Chemistry. 115:105265
In spite of possessing a wide range of pharmacological properties the anti-inflammatory activities of isoquinolin-1(2H)-ones were rarely known or explored earlier. PDE4 inhibitors on the other hand in addition to their usefulness in treating inflamma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9add33a7f9372d800168c8c55356f87d
https://doi.org/10.1016/j.bioorg.2021.105265
https://doi.org/10.1016/j.bioorg.2021.105265
Autor:
Kishore V L Parsa, Latha P Ganesan, Murugesan V S Rajaram, Mikhail A Gavrilin, Ashwin Balagopal, Nrusingh P Mohapatra, Mark D Wewers, Larry S Schlesinger, John S Gunn, Susheela Tridandapani
Publikováno v:
PLoS Pathogens, Vol 2, Iss 7, p e71 (2006)
Francisella tularensis, a Gram-negative facultative intracellular pathogen infecting principally macrophages and monocytes, is the etiological agent of tularemia. Macrophage responses to F. tularensis infection include the production of pro-inflammat
Externí odkaz:
https://doaj.org/article/4b5b0e05b4644fe5a7682d313f5389de