Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Kishore Thalluri"'
Autor:
Andy Weiss, Caitlin C. Murdoch, Katherine A. Edmonds, Matthew R. Jordan, Andrew J. Monteith, Yasiru R. Perera, Aslin M. Rodríguez Nassif, Amber M. Petoletti, William N. Beavers, Matthew J. Munneke, Sydney L. Drury, Evan S. Krystofiak, Kishore Thalluri, Hongwei Wu, Angela R.S. Kruse, Richard D. DiMarchi, Richard M. Caprioli, Jeffrey M. Spraggins, Walter J. Chazin, David P. Giedroc, Eric P. Skaar
Publikováno v:
Cell
Zinc (Zn) is an essential micronutrient and cofactor for up to 10% of proteins in living organisms. During Zn limitation, specialized enzymes called metallochaperones are predicted to allocate Zn to specific metalloproteins. This function has been pu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d31ea43627434513fb8ff4f61e85964f
https://doi.org/10.1016/j.cell.2022.04.011
https://doi.org/10.1016/j.cell.2022.04.011
Publikováno v:
Communications Chemistry, Vol 1, Iss 1, Pp 1-7 (2018)
Insulins, relaxins, and other insulin-like peptides present a longstanding synthetic challenge due to their unique cysteine-rich heterodimeric structure. While their three disulfide signature is conserved within the insulin superfamily, sequences of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30525b6b1cc0f5e1ebb9c0dd6907f97f
http://link.springer.com/article/10.1038/s42004-018-0036-9
http://link.springer.com/article/10.1038/s42004-018-0036-9
Autor:
Vasily M. Gelfanov, John P. Mayer, Xu Yang, Fa Liu, Richard D. DiMarchi, Binbin Kou, Alexander N. Zaykov, Kishore Thalluri
Publikováno v:
Journal of Peptide Science. 23:455-465
This report presents an entirely chemical, general strategy for the synthesis of relaxin-2 and insulin-like peptide 5. Historically, these two peptides have represented two of the more synthetically challenging members of the insulin superfamily. The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b45c4e4617acd655834aa8dfef869e2
https://doi.org/10.1002/psc.3010
https://doi.org/10.1002/psc.3010
Publikováno v:
Organic Letters. 19:706-709
For decades, insulin has represented a preeminent synthetic target. Recently introduced "biomimetic" strategies based on convertible single-chain precursors require incorporation of a chemical linker or a unique proteolytic site, which limits their p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eee4ab92d84d92d763e6840050018c63
https://doi.org/10.1021/acs.orglett.6b03876
https://doi.org/10.1021/acs.orglett.6b03876
Publikováno v:
Advanced Synthesis & Catalysis. 359:168-176
Boc-Oxyma (Ethyl 2-(tert-butoxycarbonyloxyimino)-2-cyanoacetate) has been reported previously as an efficient coupling reagent for the synthesis of amides, peptides, esters, thioesters and hydroxamic acids. It is known for its excellent racemization
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f037baf6da86e5fb1108a74fb0bdff93
https://doi.org/10.1002/adsc.201600661
https://doi.org/10.1002/adsc.201600661
Autor:
Tapasi Kalita, Bhubaneswar Mandal, Kishore Thalluri, Nani Babu Palakurthy, Jyoti Chandra, Dharm Dev
Publikováno v:
Asian Journal of Organic Chemistry. 5:663-675
A metal-free and catalytic method for the synthesis of 2-substituted benzoxazoles and benzothiazoles from N-protected amino acids and carboxylic acids is described. The synthesis of benzoxazole on a solid support is demonstrated by the synthesis of b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::659c7938af4d0e9efdd38e90a4d426d9
https://doi.org/10.1002/ajoc.201500527
https://doi.org/10.1002/ajoc.201500527
Publikováno v:
MedChemComm. 7:311-316
Alzheimer's disease, a severe neurodegenerative disorder, is believed to be caused by the interneuronal aggregation of the amyloid β peptide. It has no cure yet. Despite rigorous research, the mechanism of aggregation is not yet fully delineated. Es
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9251be536941dd50931cf0baf68e65f2
https://doi.org/10.1039/c5md00466g
https://doi.org/10.1039/c5md00466g
Publikováno v:
Tetrahedron Letters. 56:6108-6111
A facile, efficient, racemization-free, and environment friendly protocol for the synthesis of peptide hydroxamic acids directly from carboxylic/amino acids by ethyl 2-(tert-butoxycarbonyloxyimino)-2-cyanoacetate in the presence of DIPEA/DMAP at room
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9784b29d793bfa3c4fbd40fbad8aec51
https://doi.org/10.1016/j.tetlet.2015.09.084
https://doi.org/10.1016/j.tetlet.2015.09.084
Autor:
Kishore Thalluri, Ashim Paul, Tanmay Mondal, Krishna Chaitanya Nadimpally, Bhubaneswar Mandal
Publikováno v:
Chemical Communications. 51:2245-2248
Insertion of an anthranilic acid in an amyloidogenic peptide sequence generates a novel conformationally restricted α/β-hybrid peptide that inhibits amyloid formation of Aβ(1-40) and disrupts preformed fibrillar aggregates in vitro. Such β-sheet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3d94967bade33e4af7c1956957af6e0
https://doi.org/10.1039/c4cc09063b
https://doi.org/10.1039/c4cc09063b
Publikováno v:
RSC Adv.. 4:47841-47847
The synthesis of peptide alcohols from peptides bearing C-terminal amide using β-aminoalcohols is achieved by a simple, efficient, racemization-free (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c52f405dbd7ca2e4a09f1e729764bf2a
https://doi.org/10.1039/c4ra09091h
https://doi.org/10.1039/c4ra09091h