Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Kishore R. Alugupalli"'
Autor:
Kishore R. Alugupalli
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
None of the typhoid Vi Polysaccharide (ViPS) subunit vaccines incorporate adjuvants, and the immunogenicity of ViPS vaccines (e.g. Typbar TCV® and Typhim Vi®) is in part due to associated TLR4 ligands such as endotoxin present in these vaccines. Si
Externí odkaz:
https://doaj.org/article/041fc4a0a42c429eab49388e64fd36ad
Autor:
Kishore R. Alugupalli, Sudeep Kothari, Matthew P. Cravens, Justin A. Walker, Darren T. Dougharty, Gregory S. Dickinson, Louis A. Gatto, Andreas J. Bäumler, Tamding Wangdi, Darla R. Miller, Fernando Pardo-Manuel de Villena, Linda D. Siracusa
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract Salmonella enterica serovar Typhi is the causative agent of typhoid fever restricted to humans and does not replicate in commonly used inbred mice. Genetic variation in humans is far greater and more complex than that in a single inbred stra
Externí odkaz:
https://doaj.org/article/fb21c12f4f6245b4aadc14104da79dc1
Autor:
Akhil S, Alugupalli, Matthew P, Cravens, Justin A, Walker, Dania, Gulandijany, Gregory S, Dickinson, Genevieve, Lewis, Gudrun F, Debes, Dieter M, Schifferli, Andreas J, Bäumler, Kishore R, Alugupalli
Publikováno v:
ImmunoHorizons. 6:807-816
Circulating IgM present in the body prior to any apparent Ag exposure is referred to as natural IgM. Natural IgM provides protective immunity against a variety of pathogens. Salmonella enterica serovar Typhi (S. Typhi) is the causative agent of typho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8704777379008518f2e3ed037e642503
https://doi.org/10.4049/immunohorizons.2200088
https://doi.org/10.4049/immunohorizons.2200088
Autor:
Meihui Cheng, Jingwen Xu, Kaiyun Ding, Jing Zhang, Wei Lu, Jiansheng Liu, Jiahong Gao, Kishore R. Alugupalli, Hongqi Liu
Publikováno v:
Proceedings of the National Academy of Sciences. 119
Relapsing fever due to Borrelia hermsii is characterized by recurrent bacteremia episodes. However, infection of B. hermsii , if not treated early, can spread to various organs including the central nervous system (CNS). CNS disease manifestations ar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbcd9c36b163e96b2b9fc2866b262c9b
https://doi.org/10.1073/pnas.2205460119
https://doi.org/10.1073/pnas.2205460119
Autor:
Matthew P Cravens, Akhil S Alugupalli, Vijay K Sandilya, Stephen J McGeady, Kishore R Alugupalli
Publikováno v:
J Infect Dis
In mice, pneumococcal polysaccharide (PPS) vaccines generate antigen-specific immunoglobulin M (IgM) and immunoglobulins G1, G2, and G3. Antibody and complement-dependent opsonophagocytosis correlates with the protection induced by PPS vaccines in vi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02f7e7009be3f9eab84995b820a62913
https://europepmc.org/articles/PMC10205626/
https://europepmc.org/articles/PMC10205626/
Autor:
Justin A. Walker, Kishore R. Alugupalli, John F. Kearney, Gregory S. Dickinson, Eric A. Levenson
Publikováno v:
The Journal of Immunology. 201:1229-1240
Polysaccharide vaccines such as the Vi polysaccharide of Salmonella enterica serovar Typhi induce efficient antibody responses in adults, but not in young children. The reasons for this difference are not understood. Interleukin-7 (IL-7) dependency i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ccd249178dfe5557ad4668f495c01a31
https://doi.org/10.4049/jimmunol.1800162
https://doi.org/10.4049/jimmunol.1800162
Autor:
James P. McGettigan, Andrew G. Lytle, Kishore R. Alugupalli, Evgeni P. Tzvetkov, Joseph R Plummer, Shannon L. Haley
Publikováno v:
Antiviral Research. 144:130-137
There is significant need to develop a single-dose rabies vaccine to replace the current multi-dose rabies vaccine regimen and eliminate the requirement for rabies immune globulin in post-exposure settings. To accomplish this goal, rabies virus (RABV
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a23b1857bec6d74b6fdc95798d9ff2d
https://doi.org/10.1016/j.antiviral.2017.06.004
https://doi.org/10.1016/j.antiviral.2017.06.004
Autor:
Kishore R. Alugupalli, Tamer I. Mahmoud, John F. Kearney, Vijay K. Sandilya, Dania Gulandijany, Justin A. Walker, Vivek Belde, Akhil S. Alugupalli, Matthew P. Cravens, Andreas J. Bäumler, Isabel Palomo-Caturla
Publikováno v:
Infection and Immunity. 86
B cell antigen receptor (BCR) diversity increases by several orders of magnitude due to the action of terminal deoxynucleotidyl transferase (TdT) during V(D)J recombination. Unlike adults, infants have limited BCR diversity, in part due to reduced ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9604d4121631c7e83c9aec8d08b5d4a4
https://doi.org/10.1128/iai.00211-18
https://doi.org/10.1128/iai.00211-18
Publikováno v:
Annals of the New York Academy of Sciences. 1362:57-67
Although evidence of the protective immunity conferred by B-1b cells (CD19(+) B220(+) IgM(hi) Mac1(+) CD5(-)) has been established, the mechanisms governing the maintenance and activation of B-1b cells following pathogen encounter remain unclear. B c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9842f0f7b780484a776bcb633cf0dcf1
https://doi.org/10.1111/nyas.12772
https://doi.org/10.1111/nyas.12772
Publikováno v:
Stem cells and development. 26(23)
Immunodeficient mice transplanted with human hematopoietic stem cells (HSCs) have been referred to as “Human Immune System” (HIS) mice and are a translational platform for studying human immune responses in vivo. Human HSC sources used in generat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2a2786751944834929980a10b371c7b
https://pubmed.ncbi.nlm.nih.gov/31329744
https://pubmed.ncbi.nlm.nih.gov/31329744