Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Kishore R Anekalla"'
Autor:
Clarissa M. Koch, Andrew D. Prigge, Leah Setar, Kishore R. Anekalla, Hahn Chi Do-Umehara, Hiam Abdala-Valencia, Yuliya Politanska, Avani Shukla, Jairo Chavez, Grant R. Hahn, Bria M. Coates
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
BackgroundRespiratory syncytial virus (RSV) can cause life-threatening respiratory failure in infants. We sought to characterize the local host response to RSV infection in the nasal mucosa of infants with critical bronchiolitis and to identify early
Externí odkaz:
https://doaj.org/article/ae3cff469f85491bb96166479a22cb0a
Autor:
Jing Yang, Hanh Chi Do-Umehara, Qiao Zhang, Huashan Wang, Changchun Hou, Huali Dong, Edith A. Perez, Marc A. Sala, Kishore R. Anekalla, James M. Walter, Shuwen Liu, Richard G. Wunderink, G.R. Scott Budinger, Jing Liu
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Sepsis and acute lung injury (ALI) are linked to mitochondrial dysfunction; however, the underlying mechanism remains elusive. We previously reported that c-Jun N-terminal protein kinase 2 (JNK2) promotes stress-induced mitophagy by targeting small m
Externí odkaz:
https://doaj.org/article/c8ed6666624b4fa99b7c46a6cb604a90
Autor:
Thomas Stoeger, Rogan A. Grant, Alexandra C. McQuattie-Pimentel, Kishore R. Anekalla, Sophia S. Liu, Heliodoro Tejedor-Navarro, Benjamin D. Singer, Hiam Abdala-Valencia, Michael Schwake, Marie-Pier Tetreault, Harris Perlman, William E. Balch, Navdeep S. Chandel, Karen M. Ridge, Jacob I. Sznajder, Richard I. Morimoto, Alexander V. Misharin, G. R. Scott Budinger, Luis A. Nunes Amaral
Publikováno v:
Nature Aging. 2:1191-1206
Aging is among the most important risk factors for morbidity and mortality. To contribute toward a molecular understanding of aging, we analyzed age-resolved transcriptomic data from multiple studies. Here, we show that transcript length alone explai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0de44d4d63fdc5bb0ddd8d07ad5d272
https://doi.org/10.1038/s43587-022-00317-6
https://doi.org/10.1038/s43587-022-00317-6
Publikováno v:
F1000Research, Vol 6 (2017)
Biomedical text mining promises to assist biologists in quickly navigating the combined knowledge in their domain. This would allow improved understanding of the complex interactions within biological systems and faster hypothesis generation. New bio
Externí odkaz:
https://doaj.org/article/316d96402fa54937826b9962778acec8
Autor:
Alexander V. Misharin, Hiam Abdala-Valencia, Hanh Chi Do Umehara, William J Muller, Kishore R Anekalla, Jairo Chavez, Benjamin D. Singer, Taylor Heald-Sargent, Yuliya Politanska, Clarissa M. Koch, Andrew D. Prigge, Nikolay S. Markov, Grant R Hahn, Karen M. Ridge, Avani Shukla, L. Nelson Sanchez-Pinto, Leah Setar, Bria M. Coates
Publikováno v:
American journal of respiratory cell and molecular biology. 66(2)
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has infected more than 180 million people since the onset of the global pandemic. Despite similar viral load and infectivity rates between children and adults, children rarely develop sever
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e8b407c134ba7fde542804d26b2ca61
https://pubmed.ncbi.nlm.nih.gov/34758269
https://pubmed.ncbi.nlm.nih.gov/34758269
Autor:
Monique Hinchcliff, Monica Chi, Manu Jain, Anna P. Lam, Vince K. Morgan, Gökhan M. Mutlu, Ali Shilatifard, Luís A. Nunes Amaral, A. Christine Argento, Satoshi Watanabe, Robert D. Guzy, SeungHye Han, Ankit Bharat, Colin T. Gillespie, Stacy A. Marshall, Kishore R. Anekalla, Ching I. Chen, Kiwon Nam, Alexandra C. McQuattie-Pimentel, Alexander V. Misharin, Remzi Bag, Annette S. Flozak, Harris Perlman, Karen M. Ridge, Rohan Verma, Benjamin D. Singer, James M. Walter, Jane Dematte, Catherine A. Bonham, Stephen Chiu, Ramiro Fernandez, Ziyou Ren, Cara L. Hrusch, Saul Soberanes, Anjana Yeldandi, Francisco J. Gonzalez-Gonzalez, Nikita Joshi, Hiam Abdala-Valencia, Trevor T. Nicholson, G. R. Scott Budinger, Sangeeta Bhorade, Anne I. Sperling, Paul A. Reyfman, Mahzad Akbarpour, Jacob I. Sznajder, Deborah R. Winter, Robert B. Hamanaka, Kinola J.N. Williams, Cara J. Gottardi
Publikováno v:
American Journal of Respiratory and Critical Care Medicine
Rationale: The contributions of diverse cell populations in the human lung to pulmonary fibrosis pathogenesis are poorly understood. Single-cell RNA sequencing can reveal changes within individual cell populations during pulmonary fibrosis that are i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b5b08bd503f998ca7b47f22338bd3f5
https://doi.org/10.1164/rccm.201712-2410oc
https://doi.org/10.1164/rccm.201712-2410oc
Autor:
Alexander V. Misharin, Gökhan M. Mutlu, Ziyou Ren, James M. Walter, Nikita Joshi, Benjamin D. Singer, Satoshi Watanabe, Zhangying Chen, Ching I. Chen, Jennifer M. Davis, Thomas Stoeger, Jacob I. Sznajder, Kiwon Nam, Monica Chi, Constance E. Runyan, Ankit Bharat, G. R. Scott Budinger, Saul Soberanes, Harris Perlman, Kathryn A. Helmin, Navdeep S. Chandel, Angelo Y. Meliton, Kishore R. Anekalla, Karen M. Ridge, Paul A. Reyfman, Raul Piseaux Aillon, William E. Balch, Cara J. Gottardi, Lango Sichizya, Hiam Abdala-Valencia, Deborah R. Winter, Alexandra C. McQuattie-Pimentel, Richard I. Morimoto, Ziyan Lu
Publikováno v:
J Clin Invest
Alveolar macrophages orchestrate the response to viral infections. Age-related changes in these cells may underlie the differential severity of pneumonia in older patients. We performed an integrated analysis of single-cell RNA-Seq data that revealed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1aae453d0fc5ceac6513a64c6915ede9
https://doi.org/10.1172/jci140299
https://doi.org/10.1172/jci140299
Autor:
Bria M. Coates, Avani Shukla, Alexander V. Misharin, Taylor Heald-Sargent, Kishore R. Anekalla, Hiam Abdala-Valencia, Nikolay S. Markov, L. Nelson Sanchez-Pinto, Yuliya Politanska, Leah Setar, Andrew D. Prigge, Grant R Hahn, William J Muller, Karen M. Ridge, Jairo Chavez, Clarissa M. Koch, Hanh Chi Do-Umehara
Publikováno v:
medRxiv
article-version (status) pre
article-version (number) 1
article-version (status) pre
article-version (number) 1
RationaleDespite similar viral load and infectivity rates between children and adults infected with SARS-CoV-2, children rarely develop severe illness. Differences in the host response to the virus at the primary infection site are among the proposed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01f9e3923f0a88127eddbf4bc3f2ba4f
https://doi.org/10.1101/2021.01.26.21250269
https://doi.org/10.1101/2021.01.26.21250269
Autor:
Luisa Morales-Nebreda, Manuel A. Torres Acosta, Shang Yang Chen, Mahzad Akbarpour, Elizabeth M. Steinert, Kishore R. Anekalla, Hiam Abdala-Valencia, Paul Cheresh, Yuliya Politanska, Samuel E. Weinberg, Kathryn A. Helmin, Benjamin D. Singer
Publikováno v:
J Clin Invest
Regulatory T (Treg) cells require Foxp3 expression and induction of a specific DNA hypomethylation signature during development, after which Treg cells persist as a self-renewing population that regulates immune system activation. Whether maintenance
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13e917df56f14e6870a8da28c616783e
https://europepmc.org/articles/PMC7710299/
https://europepmc.org/articles/PMC7710299/
Autor:
Cong Chen, Kishore R. Anekalla, Rubin M. Tuder, Ankit Bharat, G. R. Scott Budinger, Xiang-Dong Fu, Jindan Yu, Peter H. S. Sporn, Catherine C. L. Wong, Qiao Zhang, Marc A. Sala, Alexander V. Misharin, Irina Petrache, Navdeep S. Chandel, Chao Peng, Jing Liu, Ping Wu, Hanh Chi Do-Umehara, Harris Perlman, Karen M. Ridge, Francisco J. Gonzalez-Gonzalez, Ravi Kalhan, Jacob I. Sznajder, Paul A. Reyfman, Hiam Abdala-Valencia, S. Marina Casalino-Matsuda
Publikováno v:
Science Advances
Lung epithelial cell–specific loss of function of Miz1 causes spontaneous COPD-like phenotype and up-regulates Ace2 in mice.
Cigarette smoking, the leading cause of chronic obstructive pulmonary disease (COPD), has been implicated as a risk fa
Cigarette smoking, the leading cause of chronic obstructive pulmonary disease (COPD), has been implicated as a risk fa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6195b88f2a722d11154c90304141500b