Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Kishore Kumar Katyayan"'
Publikováno v:
Drug Metabolism and Disposition. 48:698-707
The mass balance, excretion, and metabolism of LY3202626 were determined in healthy subjects after oral administration of a single dose of 10 mg of (approximately 100 μCi) [14C]LY3202626. Excretion of radioactivity was slow and incomplete, with appr
Autor:
Everett J. Perkins, Palaniappan Kulanthaivel, Boris A. Czeskis, Haitao Hu, Kishore Kumar Katyayan
Publikováno v:
Drug Metabolism and Disposition. 45:399-408
Mass balance and metabolism studies using radiolabeled substances are well recognized as an important part of the drug development process. In this study, we directly assessed the use of fluorine nuclear magnetic resonance (19F NMR) to achieve quanti
Autor:
Yu-Hua Hui, Kishore Kumar Katyayan
Publikováno v:
Xenobiotica; the fate of foreign compounds in biological systems. 49(12)
Dry blood spot (DBS) analysis has been extensively used for the quantitative analysis of drugs by mass spectrometry; however, utilization of DBS for qualitative metabolite profiling has been very limited. In the present study, we investigated the use
Publikováno v:
Drug Metabolism and Pharmacokinetics. 35:S31