HNF4α Antagonists Discovered by a High-Throughput Screen for Modulators of the Human Insulin Promoter

Autor: Kiselyuk, Alice, Lee, Seung-Hee, Farber-Katz, Suzette, Zhang, Mingjun, Athavankar, Sonalee, Cohen, Tom, Pinkerton, Anthony B., Ye, Mao, Bushway, Paul, Richardson, Adam D., Hostetler, Heather A., Rodriguez-Lee, Mariam, Huang, Li, Spangler, Benjamin, Smith, Layton, Higginbotham, Jennifer, Cashman, John, Freeze, Hudson, Itkin-Ansari, Pamela, Dawson, Marcia I., Schroeder, Friedhelm, Cang, Yong, Mercola, Mark, Levine, Fred

Publikováno v: In Chemistry & Biology 27 July 2012 19(7):806-818

HNF4 alpha bioactive ligands discovered by a high- throughput screen for modulators of the human insulin promoter

Autor: Kiselyuk, Alice Susan

Publikováno v: Kiselyuk, Alice Susan. (2011). HNF4 alpha bioactive ligands discovered by a high-throughput screen for modulators of the human insulin promoter. UC San Diego: Retrieved from: http://www.escholarship.org/uc/item/64k4q3gr

A number of diabetogenic stimuli interact to influence insulin promoter activity, making it an attractive target for both mechanistic studies and therapeutic interventions. Our lab developed a unique cell-based high- throughput screening assay for mo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______325::bc643a81f8367f36e3c015081ea1b8e7
http://n2t.net/ark:/20775/bb95576506

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Derivation of a Retinoid X Receptor Scaffold from Peroxisome Proliferator-Activated Receptor γ Ligand 1-Di(1 H-indol-3-yl)methyl-4-trifluoromethylbenzene.

Autor: Dawson, Marcia I., Ye, Mao, Cao, Xihua, Farhana, Lulu, Hu, Qiong-Ying, Zhao, Yong, Xu, Li Ping, Kiselyuk, Alice, Correa, Ricardo G., Yang, Li, Hou, Tingjun, Reed, John C., Itkin-Ansari, Pamela, Levine, Fred, Sanner, Michel F., Fontana, Joseph A., Zhang, Xiao-Kun

Publikováno v: ChemMedChem; 2009, Vol. 4 Issue 7, p1106-1119, 14p

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