Parkinson's Disease Skin Fibroblasts Display Signature Alterations in Growth, Redox Homeostasis, Mitochondrial Function, and Autophagy

Autor: Teves, Joji M. Y., Bhargava, Vedanshi, Kirwan, Konner R., Corenblum, Mandi J., Justiniano, Rebecca, Wondrak, Georg T., Anandhan, Annadurai, Flores, Andrew J., Schipper, David A., Khalpey, Zain, Sligh, James E., Curiel-Lewandrowski, Clara, Sherman, Scott J., Madhavan, Lalitha

The discovery of biomarkers for Parkinson's disease (PD) is challenging due to the heterogeneous nature of this disorder, and a poor correlation between the underlying pathology and the clinically expressed phenotype. An ideal biomarker would inform

Externí odkaz: http://hdl.handle.net/10150/626553
http://arizona.openrepository.com/arizona/handle/10150/626553

Parkinson's Disease Skin Fibroblasts Display Signature Alterations in Growth, Redox Homeostasis, Mitochondrial Function, and Autophagy.

Autor: Teves JMY; Graduate Interdisciplinary Program in Applied Biosciences, University of Arizona, Tucson, AZ, United States., Bhargava V; Neuroscience and Cognitive Science Undergraduate Program, Undergraduate Biology Research Program, University of Arizona, Tucson, AZ, United States., Kirwan KR; Neuroscience and Cognitive Science Undergraduate Program, Undergraduate Biology Research Program, University of Arizona, Tucson, AZ, United States., Corenblum MJ; Department of Neurology, University of Arizona, Tucson, AZ, United States., Justiniano R; Pharmacology and Toxicology, University of Arizona, Tucson, AZ, United States., Wondrak GT; Pharmacology and Toxicology, University of Arizona, Tucson, AZ, United States., Anandhan A; Department of Neurology, University of Arizona, Tucson, AZ, United States., Flores AJ; Graduate Interdisciplinary Program in Physiological Sciences, University of Arizona, Tucson, AZ, United States., Schipper DA; Department of Surgery, University of Arizona, Tucson, AZ, United States., Khalpey Z; Department of Surgery, University of Arizona, Tucson, AZ, United States., Sligh JE; Department of Medicine, University of Arizona, Tucson, AZ, United States., Curiel-Lewandrowski C; Department of Medicine, University of Arizona, Tucson, AZ, United States., Sherman SJ; Department of Neurology, University of Arizona, Tucson, AZ, United States., Madhavan L; Department of Neurology, University of Arizona, Tucson, AZ, United States.; The Evelyn F McKnight Brain Institute, University of Arizona, Tucson, AZ, United States.

Publikováno v: Frontiers in neuroscience [Front Neurosci] 2018 Jan 12; Vol. 11, pp. 737. Date of Electronic Publication: 2018 Jan 12 (Print Publication: 2017).