Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Kirupa Shanmuganathan"'
Autor:
Koudriakova T, Lakshimi Kotra, Kirupa Shanmuganathan, Cretton-Scott E, Sommadossi Jp, Chung K. Chu, Raymond F. Schinazi, Boudinot Fd, Manouilov Kk
Publikováno v:
Journal of Medicinal Chemistry. 39:4676-4681
In an effort to improve the pharmacokinetic properties and tissue distribution of 2‘-F-ara-ddI, two lipophilic prodrugs, 6-azido-2‘,3‘-dideoxy-2‘-fluoro-β-d-arabinofuranosylpurine (FAAddP, 4) and N6-methyl-2‘,3‘-dideoxy-2‘-fluoro-β-d-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::58afbd134949adc6cf44023ee11560c9
https://doi.org/10.1021/jm960140c
https://doi.org/10.1021/jm960140c
Publikováno v:
Cancer Chemotherapy and Pharmacology. 33:484-488
The pharmacokinetics of a new 2-halo-2'-deoxyadenosine analogue, 2-chloro-9-(2-deoxy-2-fluoro-beta-D-arabinofuranosyl) adenine [CL-F-ara-A], was characterized in rats following the development of a new high-performance liquid chromatography (HPLC) te
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8f14364792c88d2aba53c12786bea2c
https://doi.org/10.1007/bf00686505
https://doi.org/10.1007/bf00686505
Autor:
Kirupa Shanmuganathan, Jinfa Du, Satyanarayana Nampalli, James M. Gallo, Raymond F. Schinazi, Tatiana Koudriakova, Chung K. Chu
Publikováno v:
Journal of medicinal chemistry. 37(6)
In order to enhance the brain delivery of 2'-F-ara-ddI,2'-F-ara-ddP 6 was synthesized and its in vitro and in vivo bioconversion reaction studied. For the study, a new efficient synthetic method for 2'-F-ara-ddP 6 was developed from 5-benzoyl-1,2-O-i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b429efc906080b2b175655d3b519fa7
https://pubmed.ncbi.nlm.nih.gov/8145233
https://pubmed.ncbi.nlm.nih.gov/8145233