Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Kirti Snigdha"'
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
Glioblastoma Multiforme (GBM) is the most common form of malignant brain tumor with poor prognosis. Amplification of Epidermal Growth Factor Receptor (EGFR), and mutations leading to activation of Phosphatidyl-Inositol-3 Kinase (PI3K) pathway are com
Externí odkaz:
https://doaj.org/article/04a13be558004b1ebe850d9bcdbf8a84
Autor:
Kirti Snigdha, Karishma Sanjay Gangwani, Gauri Vijay Lapalikar, Amit Singh, Madhuri Kango-Singh
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 7 (2019)
Hippo pathway was initially identified through genetic screens for genes regulating organ size in fruitflies. Recent studies have highlighted the role of Hippo signaling as a key regulator of homeostasis, and in tumorigenesis. Hippo pathway is compri
Externí odkaz:
https://doaj.org/article/d1671bdc2abb4a9680d75e078f4256aa
Autor:
Mutsuko Minata, Alessandra Audia, Junfeng Shi, Songjian Lu, Joshua Bernstock, Marat S. Pavlyukov, Arvid Das, Sung-Hak Kim, Yong Jae Shin, Yeri Lee, Harim Koo, Kirti Snigdha, Indrayani Waghmare, Xing Guo, Ahmed Mohyeldin, Daniel Gallego-Perez, Jia Wang, Dongquan Chen, Peng Cheng, Farah Mukheef, Minerva Contreras, Joel F. Reyes, Brian Vaillant, Erik P. Sulman, Shi-Yuan Cheng, James M. Markert, Bakhos A. Tannous, Xinghua Lu, Madhuri Kango-Singh, L. James Lee, Do-Hyun Nam, Ichiro Nakano, Krishna P. Bhat
Publikováno v:
Cell Reports, Vol 26, Iss 7, Pp 1893-1905.e7 (2019)
Summary: Unresectable glioblastoma (GBM) cells in the invading tumor edge can act as seeds for recurrence. The molecular and phenotypic properties of these cells remain elusive. Here, we report that the invading edge and tumor core have two distinct
Externí odkaz:
https://doaj.org/article/10c885e108604068b2ac13b7bda6733f
Autor:
Zhimin Liu, Zuodong Jiang, Geoffrey Kip, Kirti Snigdha, Jennings Xu, Xiaoying Wu, Najat Khan, Timothy Schultz
Publikováno v:
Pattern recognition letters. 158
The outbreak of the SARS-CoV-2 novel coronavirus has caused a health crisis of immeasurable magnitude. Signals from heterogeneous public data sources could serve as early predictors for infection waves of the pandemic, particularly in its early phase
Presence of inflammatory factors in the tumor microenvironment is well known yet their specific role in tumorigenesis is elusive. The core inflammatory pathways are conserved inDrosophila, including the Toll-Like Receptor (TLR) and the Tumor Necrosis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::698dcc59a1dd4e37001b93fef844b35a
https://doi.org/10.1101/2020.08.16.253005
https://doi.org/10.1101/2020.08.16.253005
Publikováno v:
Molecular Genetics of Axial Patterning, Growth and Disease in Drosophila Eye ISBN: 9783030422455
Cancer is a devastating disease resulting from uncontrolled cell proliferation producing tumors and invasion/metastasis of cells resulting in secondary tumors. The underlying genetic defects occur in oncogenes and tumor suppressor genes and in genes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::52f7ef21670acb46cfa18e6a0db46101
https://doi.org/10.1007/978-3-030-42246-2_9
https://doi.org/10.1007/978-3-030-42246-2_9
Publikováno v:
Frontiers in Cell and Developmental Biology
Glioblastoma Multiforme (GBM) is the most common form of malignant brain tumor with poor prognosis. Amplification of Epidermal Growth Factor Receptor (EGFR), and mutations leading to activation of Phosphatidyl-Inositol-3 Kinase (PI3K) pathway are com
Publikováno v:
Oncogene. 40(24)
Presence of inflammatory factors in the tumor microenvironment is well-documented yet their specific role in tumorigenesis is elusive. The core inflammatory pathways like the Toll-Like Receptor (TLR) and the Tumor Necrosis Factor (TNF) pathway are co
Publikováno v:
Soft Matter. 11:5353-5364
Hydrogels of low molecular weight molecules are important in biomedical applications. Multiple factors are responsible for hydrogel formation, but their role in governing self-assembly to hydrogel formation is poorly understood. Herein, we report the
Autor:
Shi Yuan Cheng, Dongquan Chen, Jia Wang, Ichiro Nakano, Marat S. Pavlyukov, Yeri Lee, Krishna P. Bhat, James M. Markert, Xinghua Lu, Indrayani Waghmare, Junfeng Shi, Ahmed Mohyeldin, Bakhos A. Tannous, Songjian Lu, Mutsuko Minata, Peng Cheng, Minerva Contreras, Madhuri Kango-Singh, Do Hyun Nam, Xing Guo, Alessandra Audia, Joshua D. Bernstock, Brian Vaillant, Yong Jae Shin, Daniel Gallego-Perez, Sung Hak Kim, L. James Lee, Arvid Das, Erik P. Sulman, Joel F. Reyes, Farah Mukheef, Harim Koo, Kirti Snigdha
Publikováno v:
Cell Reports, Vol 26, Iss 7, Pp 1893-1905.e7 (2019)
Cell reports
Cell reports
SUMMARY Unresectable glioblastoma (GBM) cells in the invading tumor edge can act as seeds for recurrence. The molecular and phenotypic properties of these cells remain elusive. Here, we report that the invading edge and tumor core have two distinct t