Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Kirthi C. Reddy"'
Autor:
Mara H. Cowen, Dustin Haskell, Kristi Zoga, Kirthi C. Reddy, Sreekanth H. Chalasani, Michael P. Hart
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Animal foraging is an essential and evolutionarily conserved behavior that occurs in social and solitary contexts, but the underlying molecular pathways are not well defined. We discover that conserved autism-associated genes (NRXN1(nrx-1),
Externí odkaz:
https://doaj.org/article/375c96d0ad564a7ea11bdc9170d22820
Autor:
Vladimir Lažetić, Fengting Wu, Lianne B. Cohen, Kirthi C. Reddy, Ya-Ting Chang, Spencer S. Gang, Gira Bhabha, Emily R. Troemel
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
Intestinal immune responses to intracellular infection of Caenorhabditis elegans and other Invertebrate hosts are not well understood. Here the authors show a key role for the transcription factor ZIP-1 during intestinal intracellular infection.
Externí odkaz:
https://doaj.org/article/ac06bf6f7e8447588327313482be2b7f
Autor:
Spencer S Gang, Manish Grover, Kirthi C Reddy, Deevya Raman, Ya-Ting Chang, Damian C Ekiert, Michalis Barkoulas, Emily R Troemel
Publikováno v:
PLoS Genetics, Vol 18, Iss 10, p e1010314 (2022)
Regulation of immunity throughout an organism is critical for host defense. Previous studies in the nematode Caenorhabditis elegans have described an "ON/OFF" immune switch comprised of the antagonistic paralogs PALS-25 and PALS-22, which regulate re
Externí odkaz:
https://doaj.org/article/538bfe5c9edc48ddbfd2c5f488e5aca2
Autor:
Molly A Matty, Hiu E Lau, Jessica A Haley, Anupama Singh, Ahana Chakraborty, Karina Kono, Kirthi C Reddy, Malene Hansen, Sreekanth H Chalasani
Publikováno v:
PLoS Genetics, Vol 18, Iss 5, p e1010178 (2022)
Animals integrate changes in external and internal environments to generate behavior. While neural circuits detecting external cues have been mapped, less is known about how internal states like hunger are integrated into behavioral outputs. Here, we
Externí odkaz:
https://doaj.org/article/24d347034e084c988e84912fc183e849
Publikováno v:
PLoS ONE, Vol 17, Iss 5, p e0267698 (2022)
Ultrasound has been shown to affect the function of both neurons and non-neuronal cells, but, the underlying molecular machinery has been poorly understood. Here, we show that at least two mechanosensitive proteins act together to generate C. elegans
Externí odkaz:
https://doaj.org/article/31eae6f7107042d7b39bf9299b537df4
Prey respond to predators by altering their behavior to optimize their own fitness and survival. Specifically, prey are known to avoid predator-occupied territories to reduce their risk of harm or injury to themselves and their progeny. We probe the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::13603dccacf79375b6e8d475a6b65b74
https://doi.org/10.1101/2022.10.06.511234
https://doi.org/10.1101/2022.10.06.511234
Autor:
Spencer S. Gang, Manish Grover, Kirthi C. Reddy, Deevya Raman, Ya-Ting Chang, Damian C. Ekiert, Michalis Barkoulas, Emily R. Troemel
Regulation of immunity throughout an organism is critical for host defense. Previous studies in the nematode Caenorhabditis elegans have described an “ON/OFF” immune switch comprised of the antagonistic paralogs PALS-25 and PALS-22, which regulat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea4de4f8dcaaa19feb0736358eb72b16
https://doi.org/10.1101/2022.06.28.497889
https://doi.org/10.1101/2022.06.28.497889
Autor:
Douglas J Cattie, Claire E Richardson, Kirthi C Reddy, Elan M Ness-Cohn, Rita Droste, Mary K Thompson, Wendy V Gilbert, Dennis H Kim
Publikováno v:
PLoS Genetics, Vol 12, Iss 9, p e1006326 (2016)
The translation initiation factor eIF3 is a multi-subunit protein complex that coordinates the assembly of the 43S pre-initiation complex in eukaryotes. Prior studies have demonstrated that not all subunits of eIF3 are essential for the initiation of
Externí odkaz:
https://doaj.org/article/945edc35e80548d9a13d3b939a1dbfdf
Autor:
Anupama Singh, Bhagyashree Kaduskar, Kirthi C Reddy, Caroline Kumsta, Ethan Bier, Malene Hansen, Sreekanth H Chalasani
Age-related decline in intestinal barrier function impacts survival across species, but the underlying cell intrinsic and extrinsic factors remain unclear. Here, we demonstrate a role for neuropeptides in regulating aging-associated increases in inte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::58a2ab7d91fdf2071b39cefe5479b9b9
https://doi.org/10.1101/2022.02.24.481867
https://doi.org/10.1101/2022.02.24.481867
Autor:
Uri Magaram, Connor Weiss, Aditya Vasan, Kirthi C. Reddy, James Friend, Sreekanth H. Chalasani
Publikováno v:
PloS one, vol 17, iss 5
Ultrasound has been shown to affect the function of both neurons and non-neuronal cells, but, the underlying molecular machinery has been poorly understood. Here, we show that at least two mechanosensitive proteins act together to generate C. elegans
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36c94869ee1b86e95af2e2f5b547887f
https://pubmed.ncbi.nlm.nih.gov/35511952
https://pubmed.ncbi.nlm.nih.gov/35511952