Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Kirsty Wienand"'
Autor:
Fabian Frontzek, Annette M. Staiger, Myroslav Zapukhlyak, Wendan Xu, Irina Bonzheim, Vanessa Borgmann, Philip Sander, Maria Joao Baptista, Jan-Niklas Heming, Philipp Berning, Ramona Wullenkord, Tabea Erdmann, Mathias Lutz, Pia Veratti, Sophia Ehrenfeld, Kirsty Wienand, Heike Horn, John R. Goodlad, Matthew R. Wilson, Ioannis Anagnostopoulos, Mario Lamping, Eva Gonzalez-Barca, Fina Climent, Antonio Salar, Josep Castellvi, Pau Abrisqueta, Javier Menarguez, Teresa Aldamiz, Julia Richter, Wolfram Klapper, Alexandar Tzankov, Stefan Dirnhofer, Andreas Rosenwald, José Luis Mate, Gustavo Tapia, Peter Lenz, Cornelius Miething, Wolfgang Hartmann, Björn Chapuy, Falko Fend, German Ott, José-Tomas Navarro, Michael Grau, Georg Lenz
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Plasmablastic lymphoma (PBL) is an aggressive lymphoma subtype characterized by poor prognosis but the molecular knowledge of the disease is limited. Here, the authors perform whole exome sequencing and copy number determination of primary samples hi
Externí odkaz:
https://doaj.org/article/6d054d5ed82e4409b9428afb7baa476b
Autor:
Kirsty Wienand, Bjoern Chapuy, Chip Stewart, Andrew J. Dunford, David Wu, Jaegil Kim, Atanas Kamburov, Timothy R. Wood, Fathima Zumla Cader, Matthew D. Ducar, Aaron R. Thorner, Anwesha Nag, Alexander T. Heubeck, Michael J. Buonopane, Robert A. Redd, Kamil Bojarczuk, Lee N. Lawton, Philippe Armand, Scott J. Rodig, Jonathan R. Fromm, Gad Getz, Margaret A. Shipp
Publikováno v:
Blood Advances, Vol 3, Iss 23, Pp 4065-4080 (2019)
Abstract: Classical Hodgkin lymphoma (cHL) is composed of rare malignant Hodgkin Reed-Sternberg (HRS) cells within an extensive, but ineffective, inflammatory/immune cell infiltrate. HRS cells exhibit near-universal somatic copy gains of chromosome 9
Externí odkaz:
https://doaj.org/article/fb5ce2af40844774bf1b968171dded99
Autor:
Linfeng Chen, Jing Ouyang, Kirsty Wienand, Kamil Bojarczuk, Yansheng Hao, Bjoern Chapuy, Donna Neuberg, Przemyslaw Juszczynski, Lee N. Lawton, Scott J. Rodig, Stefano Monti, Margaret A. Shipp
Publikováno v:
Haematologica, Vol 105, Iss 5 (2020)
B-cell receptor (BCR) signaling pathway components represent promising treatment targets in multiple B-cell malignancies including diffuse large B-cell lymphoma (DLBCL). In in vitro and in vivo model systems, a subset of DLBCLs depend upon BCR surviv
Externí odkaz:
https://doaj.org/article/e45df442ab06411b89d31bae3d7a29df
Autor:
Kirsty Wienand, Margaret A. Shipp
Publikováno v:
HemaSphere, Vol 2, Pp 90-92 (2018)
Externí odkaz:
https://doaj.org/article/187f3664cbf045eb8a98f1cec52746bf
Autor:
Kirsty Wienand, Karen Shires
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0120734 (2015)
The malignant cell phenotype of Multiple Myeloma (MM) remains unclear with studies proposing it to be either clonotypic B or proliferating plasma cells. Cancer/testis antigen MAGE C1 is being extensively studied in MM and it has been suggested that i
Externí odkaz:
https://doaj.org/article/7be4fab70ffe457999a78279ac2a16ee
Autor:
Kirsty Wienand, Samantha Stokes, Philip G. Montgomery, Kelly Sullivan, Joshua M. Dempster, William C. Hahn, Jennifer A. Roth, Francisca Vazquez
Publikováno v:
Cancer Research. 83:LB074-LB074
Cancer genome alterations that cause cancer cells to grow also confer vulnerabilities, which normal cells lack. The challenge is that, for the majority of cancers, we do not understand the relationship between the genetic alterations and the dependen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7a6c7b3f3ae05e79e67ff3440118ed78
https://doi.org/10.1158/1538-7445.am2023-lb074
https://doi.org/10.1158/1538-7445.am2023-lb074
Autor:
Agusti Alentorn, Isaias Hernández-Verdin, Eva Kirasic, Kirsty Wienand, Sandrine Eimer, Hugues Loiseau, Audrey Rousseau, Jérôme Paillassa, Guido Ahle, Felix Lerintiu, Emmanuelle Uro-Coste, Lucie Oberic, Dominique Figarella-Branger, Olivier Chinot, Guillaume Gauchotte, Luc Taillandier, Jean-Pierre Marolleau, Marc Polivka, Clovis Adam, Renata Ursu, Anna Schimitt, Noemie Barillot, Lucia Nichelli, Fernando Lozano-Sánchez, Maria-José Ibañez-Juliá, Matthieu Peyre, Bertrand Mathon, Yah-se Abada, Frederic Charlotte, Frédéric Davi, Chip Stewart, Aurélien de Reyniès, Sylvain Choquet, Carole Soussain, Caroline Houillier, Bjoern Chapuy, Khe Hoang-Xuan
Primary central nervous system lymphoma (PCNSL) is a distinct extranodal lymphoma presenting with limited stage disease but variable response rates to treatment despite homogenous pathological presentation. The likely underlying molecular heterogenei
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1a906a05dad06be48c44d736b6668616
https://doi.org/10.21203/rs.3.rs-1438980/v1
https://doi.org/10.21203/rs.3.rs-1438980/v1
Autor:
Wenjiang Ma, Philippe Armand, Pei-Hsuan Chen, Jason L. Weirather, Xihao Hu, Fathima Zumla Cader, Lee N. Lawton, Margaret A. Shipp, Ron C. J. Schackmann, Robert A. Redd, Elisa Mandato, Jing Ouyang, Scott J. Rodig, Walter Goh, Bo Li, Donna Neuberg, Kirsty Wienand, X. Shirley Liu
Publikováno v:
Nat Med
PD-1 blockade is highly effective in classical Hodgkin lymphomas (cHLs), which exhibit frequent copy-number gains of CD274 (PD-L1) and PDC1LG2 (PD-L2) on chromosome 9p24.1. However, in this largely MHC-class-I-negative tumor, the mechanism of action
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf708a4672044835c3e5a2c915d086c3
https://doi.org/10.1038/s41591-020-1006-1
https://doi.org/10.1038/s41591-020-1006-1
Autor:
Scott J. Rodig, Bjoern Chapuy, Donna Neuberg, Kirsty Wienand, Stefano Monti, Przemyslaw Juszczynski, Linfeng Chen, Margaret A. Shipp, Kamil Bojarczuk, Lee N. Lawton, Yansheng Hao, Jing Ouyang
Publikováno v:
Haematologica
B-cell receptor (BCR) signaling pathway components represent promising treatment targets in multiple B-cell malignancies including diffuse large B-cell lymphoma (DLBCL). In in vitro and in vivo model systems, a subset of DLBCLs depend upon BCR surviv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9bbe9829a320087ddd4e6b32c07f6544
http://europepmc.org/articles/PMC7193488
http://europepmc.org/articles/PMC7193488
Autor:
Björn Chapuy, Kirsty Wienand
Publikováno v:
Hematological oncologyREFERENCES. 39
Aggressive large B-cell lymphomas (LBCLs) represent a frequent but clinically and molecularly heterogeneous group of tumors. Technological advances over the last decades prompted the development of different classification schemas to either sharpen d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75af333d32a601584ace58a71b0d6432
https://pubmed.ncbi.nlm.nih.gov/34105819
https://pubmed.ncbi.nlm.nih.gov/34105819