Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Kirsty S. Nicolson"'
Autor:
William J Sanderson, David C. Wraith, Streeter Heather Barbara, Kirsty S. Nicolson, Evelien Schurgers, Katrien Pletinckx, Lotta Jansson
Publikováno v:
Blood advances. 6(7)
Haemophilia A (HA) is a blood clotting disorder caused by various genetic deficiencies in the factor VIII (FVIII) encoding F8 gene. Patients receiving FVIII replacement therapy are at risk of developing neutralizing antibodies (FVIII inhibitors) rend
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::060cccbd84accabd019fcf3366798102
https://pubmed.ncbi.nlm.nih.gov/34529764
https://pubmed.ncbi.nlm.nih.gov/34529764
Autor:
David C. Wraith, Streeter Heather Barbara, Johan Verhagen, Catherine A Sabatos-Peyton, Kirsty S. Nicolson, David J. Morgan, Leona Gabryšová
Publikováno v:
The Journal of Experimental Medicine
Regulation of the immune response to self- and foreign antigens is vitally important for limiting immune pathology associated with both infections and hypersensitivity conditions. Control of autoimmune conditions can be reinforced by tolerance induct
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53a41939355b8c73258f90a1fe3371ee
https://doi.org/10.1084/jem.20082118
https://doi.org/10.1084/jem.20082118
Autor:
Kirsty S. Nicolson, David C. Wraith
Publikováno v:
Inflammation & Allergy-Drug Targets. 5:141-148
Recent advances in immunology have greatly increased our understanding of immunological tolerance. In particular, there has been a resurgence of interest in mechanisms of immune regulation. Immune regulation refers to the phenomenon, previously known
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::856cd89369eec64fb960538194866f8e
https://doi.org/10.2174/187152806778256098
https://doi.org/10.2174/187152806778256098
Autor:
David C. Wraith, Anette Sundstedt, Sophie Minaee, Kirsty S. Nicolson, Emma J. O’Neill, Streeter Heather Barbara
Publikováno v:
The Journal of Immunology. 176:5329-5337
Recent studies have emphasized the importance of T cells with regulatory/suppressor properties in controlling autoimmune diseases. A number of different types of regulatory T cells have been described with the best characterized being the CD25+ popul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e722fce97ab742e1bafce4c11c7c2b2
https://doi.org/10.4049/jimmunol.176.9.5329
https://doi.org/10.4049/jimmunol.176.9.5329
Autor:
Per Anderson, Sophie Minaee, David C. Wraith, Li Li, Anette Sundstedt, Zihni Acar Yazici, Kirsty S. Nicolson, Ping Wang, R T Woolf, Suling Li, Nathaniel T Whitley
Publikováno v:
The Journal of Immunology. 174:310-319
Intranasal administration of peptide Ac1–9[4Y], based on the N-terminal epitope of myelin basic protein, can induce CD4+ T cell tolerance, and suppress experimental autoimmune encephalomyelitis induction. The peptide-induced regulatory T (PI-TReg)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1fa1aa54b10ba11c1c9b87bbfa520c20
https://doi.org/10.4049/jimmunol.174.1.310
https://doi.org/10.4049/jimmunol.174.1.310
Autor:
Anette Sundstedt, Emma J. O’Neill, Leslie Saurer, Kirsty S. Nicolson, David C. Wraith, Ponsford Mary, Graziella Mazza, Steve Anderton, Streeter Heather Barbara
Publikováno v:
Annals of the New York Academy of Sciences. 1029:180-192
Mucosal antigen delivery can induce tolerance, as shown by suppression of subsequent responses to antigen. Our previous work showed that both intranasal and oral routes of antigen delivery were effective but indicated that the intranasal route might
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fee08a790d1933bfbe742aedcea7ed14
https://doi.org/10.1196/annals.1309.034
https://doi.org/10.1196/annals.1309.034
Publikováno v:
The Journal of Immunology. 170:1240-1248
Regulatory CD4+ T cells were induced in the Tg4 TCR transgenic mouse specific for the N-terminal peptide (Ac1-9) of myelin basic protein by intranasal administration of a high-affinity MHC-binding analog (Ac1-9[4Y]). Peptide-induced tolerant cells (P
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::992901e088774d9ec9edb85525c393c3
https://doi.org/10.4049/jimmunol.170.3.1240
https://doi.org/10.4049/jimmunol.170.3.1240
Autor:
Per Anderson, David C. Wraith, Kirsty S. Nicolson, María Elena Rodríguez-Cabezas, Alistair L. J. Symonds, Anette Sundstedt, Suling Li, Ping Wang, Sabah Khalid, Barbara Ada Manzo, Sophie Minaee
Repetitive antigen stimulation induces peripheral T cell tolerance in vivo. It is not known, however, whether multiple stimulations merely suppress T cell activation or, alternatively, change the transcriptional program to a distinct, tolerant state.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1b0876cd91cd1fccb1be3ee0ee82af9
https://europepmc.org/articles/PMC2652694/
https://europepmc.org/articles/PMC2652694/
Publikováno v:
Current opinion in immunology. 16(6)
The immune system is a delicately balanced network of interacting cells. In recent years, the concept of immune regulation/suppression has been firmly established, and both natural and induced regulatory cells play vital roles in protection from auto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ba3e4442ff679ffa0567aca5edbd51d
https://pubmed.ncbi.nlm.nih.gov/15511660
https://pubmed.ncbi.nlm.nih.gov/15511660