Výsledky vyhledávání - "Kirsty S. Brown"

FcγRIIb-mediated negative regulation of BCR signalling is associated with the recruitment of the MAPkinase-phosphatase, Pac-1, and the 3′-inositol phosphatase, PTEN

Autor: Derek Blair, Emma K. Nicholson, Steven D. Reid, Margaret M. Harnett, Kirsty S. Brown

Publikováno v: Cellular Signalling. 16:71-80

The low-affinity receptor for IgG, FcgammaRIIb, negatively regulates B cell antigen receptor (BCR)-mediated proliferative signalling. FcgammaRIIb has been reported to mediate this inhibition by uncoupling the BCR from the RasMAPkinase pathway. We now

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50adaf7a6c38d324e0fcbc75832de6dc
https://doi.org/10.1016/s0898-6568(03)00113-x

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Hyporesponsiveness of murine B lymphocytes exposed to the filarial nematode secreted product ES-62 in vivo

Autor: Elad Katz, Emma H. Wilson, J. E. O'Grady, Margaret M. Harnett, Kirsty S. Brown, Maureen R. Deehan, Katrina M. Houston, William Harnett

Publikováno v: Immunology. 109:238-245

ES-62 is a phosphorylcholine (PC)-containing glycoprotein secreted by filarial nematodes, parasites of vertebrates including humans. We have previously demonstrated that pre-exposure to this molecule in vitro interferes with subsequent B-cell recepto

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be24c06afd5de9869974539443efd58e
https://doi.org/10.1046/j.1365-2567.2003.01661.x

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