Zobrazeno 1 - 10
of 152
pro vyhledávání: '"Kirsty R Short"'
Autor:
Nathalie A J Verzele, Brendon Y Chua, Kirsty R Short, Aung Aung Kywe Moe, Isaac N Edwards, Helle Bielefeldt-Ohmann, Katina D Hulme, Ellesandra C Noye, Marcus Z W Tong, Patrick C Reading, Matthew W Trewella, Stuart B Mazzone, Alice E McGovern
Publikováno v:
PLoS Pathogens, Vol 20, Iss 4, p e1011635 (2024)
Influenza A virus (IAV) is a common respiratory pathogen and a global cause of significant and often severe morbidity. Although inflammatory immune responses to IAV infections are well described, little is known about how neuroimmune processes contri
Externí odkaz:
https://doaj.org/article/0301a849f93546c297d1e30175947711
Autor:
Marcus ZW Tong, Julian DJ Sng, Meagan Carney, Lucy Cooper, Samuel Brown, Katie E Lineburg, Keng Yih Chew, Neve Collins, Kirsten Ignacio, Megan Airey, Lucy Burr, Briony A Joyce, Dhilshan Jayasinghe, Christopher LD McMillan, David A Muller, Anurag Adhikari, Linda A Gallo, Emily S Dorey, Helen L Barrett, Stephanie Gras, Corey Smith, Kim Good‐Jacobson, Kirsty R Short
Publikováno v:
Clinical & Translational Immunology, Vol 12, Iss 12, Pp n/a-n/a (2023)
ABSTRACT Objective Class III obesity (body mass index [BMI] ≥ 40 kg m−2) significantly impairs the immune response to SARS‐CoV‐2 vaccination. However, the effect of an elevated BMI (≥ 25 kg m−2) on humoral immunity to SARS‐CoV‐2 infec
Externí odkaz:
https://doaj.org/article/656608753bfc4d1498ed16cc174b0aab
Autor:
Azam Asanjarani, Aminath Shausan, Keng Chew, Thomas Graham, Shane G Henderson, Hermanus M Jansen, Kirsty R Short, Peter G Taylor, Aapeli Vuorinen, Yuvraj Yadav, Ilze Ziedins, Yoni Nazarathy
Publikováno v:
PLOS Digital Health, Vol 1, Iss 12, p e0000142 (2022)
We describe an experimental setup and a currently running experiment for evaluating how physical interactions over time and between individuals affect the spread of epidemics. Our experiment involves the voluntary use of the Safe Blues Android app by
Externí odkaz:
https://doaj.org/article/e7ce4467a154477aa8c1543a6a28fa45
Autor:
Yanshan Zhu, Keng Yih Chew, Melanie Wu, Anjana C Karawita, Georgina McCallum, Lauren E Steele, Ayaho Yamamoto, Larisa I Labzin, Tejasri Yarlagadda, Alexander A Khromykh, Xiaohui Wang, Julian D J Sng, Claudia J Stocks, Yao Xia, Tobias R Kollmann, David Martino, Merja Joensuu, Frédéric A Meunier, Giuseppe Balistreri, Helle Bielefeldt-Ohmann, Asha C Bowen, Anthony Kicic, Peter D Sly, Kirsten M Spann, Kirsty R Short
Publikováno v:
PLoS Biology, Vol 20, Iss 8, p e3001728 (2022)
Children typically experience more mild symptoms of Coronavirus Disease 2019 (COVID-19) when compared to adults. There is a strong body of evidence that children are also less susceptible to Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2
Externí odkaz:
https://doaj.org/article/a26c38131664476296b2cb3b91aefadf
Autor:
Archana Panikkar, Katie E Lineburg, Jyothy Raju, Keng Yih Chew, George R Ambalathingal, Sweera Rehan, Srividhya Swaminathan, Pauline Crooks, Laetitia Le Texier, Leone Beagley, Shannon Best, Matthew Solomon, Katherine K Matthews, Sriganesh Srihari, Michelle A Neller, Kirsty R Short, Rajiv Khanna, Corey Smith
Publikováno v:
PLoS Pathogens, Vol 18, Iss 2, p e1010339 (2022)
Adoptive T-cell immunotherapy has provided promising results in the treatment of viral complications in humans, particularly in the context of immunocompromised patients who have exhausted all other clinical options. The capacity to expand T cells fr
Externí odkaz:
https://doaj.org/article/c3b87232ebed482692dd6783b41f36ec
Autor:
Michail Yekelchyk, Esha Madan, Jochen Wilhelm, Kirsty R Short, António M Palma, Linbu Liao, Denise Camacho, Everlyne Nkadori, Michael T Winters, Emily S Rice, Inês Rolim, Raquel Cruz‐Duarte, Christopher J Pelham, Masaki Nagane, Kartik Gupta, Sahil Chaudhary, Thomas Braun, Raghavendra Pillappa, Mark S Parker, Thomas Menter, Matthias Matter, Jasmin Dionne Haslbauer, Markus Tolnay, Kornelia D Galior, Kristina A Matkwoskyj, Stephanie M McGregor, Laura K Muller, Emad A Rakha, Antonio Lopez‐Beltran, Ronny Drapkin, Maximilian Ackermann, Paul B Fisher, Steven R Grossman, Andrew K Godwin, Arutha Kulasinghe, Ivan Martinez, Clay B Marsh, Benjamin Tang, Max S Wicha, Kyoung Jae Won, Alexandar Tzankov, Eduardo Moreno, Rajan Gogna
Publikováno v:
EMBO Molecular Medicine, Vol 13, Iss 11, Pp n/a-n/a (2021)
Abstract Risk stratification of COVID‐19 patients is essential for pandemic management. Changes in the cell fitness marker, hFwe‐Lose, can precede the host immune response to infection, potentially making such a biomarker an earlier triage tool.
Externí odkaz:
https://doaj.org/article/f8eb078fb27a469bb4350f69d131fd6a
Autor:
Pengcheng Zhou, Jiali Chen, Jing He, Ting Zheng, Joseph Yunis, Victor Makota, Yannick O Alexandre, Fang Gong, Xia Zhang, Wuxiang Xie, Yuhui Li, Miao Shao, Yanshan Zhu, Jane E Sinclair, Miao Miao, Yaping Chen, Kirsty R Short, Scott N Mueller, Xiaolin Sun, Di Yu, Zhanguo Li
Publikováno v:
PLoS Pathogens, Vol 17, Iss 10, p e1009858 (2021)
Autoimmune diseases are often treated by glucocorticoids and immunosuppressive drugs that could increase the risk for infection, which in turn deteriorate disease and cause mortality. Low-dose IL-2 (Ld-IL2) therapy emerges as a new treatment for a wi
Externí odkaz:
https://doaj.org/article/6892f12d515d4852b12e973d2e669c97
Autor:
Katina D Hulme, Anjana C Karawita, Cassandra Pegg, Myrna JM Bunte, Helle Bielefeldt-Ohmann, Conor J Bloxham, Silvie Van den Hoecke, Yin Xiang Setoh, Bram Vrancken, Monique Spronken, Lauren E Steele, Nathalie AJ Verzele, Kyle R Upton, Alexander A Khromykh, Keng Yih Chew, Maria Sukkar, Simon Phipps, Kirsty R Short
Publikováno v:
eLife, Vol 10 (2021)
Influenza virus has a high mutation rate, such that within one host different viral variants can emerge. Evidence suggests that influenza virus variants are more prevalent in pregnant and/or obese individuals due to their impaired interferon response
Externí odkaz:
https://doaj.org/article/bf6df5e1336e47158a87381401c4414d
Autor:
Kei Sato, Jane E Sinclair, Habib Sadeghirad, John F Fraser, Kirsty R Short, Arutha Kulasinghe
Publikováno v:
Clinical & Translational Immunology, Vol 10, Iss 9, Pp n/a-n/a (2021)
Abstract Pre‐existing cardiovascular disease (CVD) increases the morbidity and mortality of COVID‐19 and is strongly associated with poor disease outcomes. However, SARS‐CoV‐2 infection can also trigger de novo acute and chronic cardiovascula
Externí odkaz:
https://doaj.org/article/08bcd3eee61a484fa0195992647f7507
Autor:
Lilian Schimmel, Keng Yih Chew, Claudia J Stocks, Teodor E Yordanov, Patricia Essebier, Arutha Kulasinghe, James Monkman, Anna Flavia Ribeiro dosSantos Miggiolaro, Caroline Cooper, Lucia deNoronha, Kate Schroder, Anne Karine Lagendijk, Larisa I Labzin, Kirsty R Short, Emma J Gordon
Publikováno v:
Clinical & Translational Immunology, Vol 10, Iss 10, Pp n/a-n/a (2021)
Abstract Objectives Thrombotic and microvascular complications are frequently seen in deceased COVID‐19 patients. However, whether this is caused by direct viral infection of the endothelium or inflammation‐induced endothelial activation remains
Externí odkaz:
https://doaj.org/article/fb13a66448274e4d8345aa44e4f79908