Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Kirsty Olsen"'
Publikováno v:
SAGE Open Medicine, Vol 12 (2024)
Objectives: Dementia with Lewy bodies is characterised by rapid fluctuations in attention, which are known as “cognitive fluctuations.” Despite the fact that cognitive fluctuations are considered to be a core dementia with Lewy bodies symptom, th
Externí odkaz:
https://doaj.org/article/ea2d68118d9e4f43b5b52606f61644a3
Autor:
Michael J. Firbank, Katrina daSilva Morgan, Daniel Collerton, Greg J. Elder, Jehill Parikh, Kirsty Olsen, Julia Schumacher, Dominic ffytche, John-Paul Taylor
Publikováno v:
NeuroImage: Clinical, Vol 35, Iss , Pp 103041- (2022)
Background and objectives: In Charles Bonnet Syndrome (CBS), visual hallucinations (VH) are experienced by people with sight loss due to eye disease or lesional damage to early visual pathways. The aim of this cross-sectional study was to investigate
Externí odkaz:
https://doaj.org/article/faf9e4d5d32948b6b7185cff777a9332
Autor:
Paul C. Donaghy, Michael Firbank, George Petrides, Jim Lloyd, Nicola Barnett, Kirsty Olsen, Amanda Heslegrave, Henrik Zetterberg, Alan J. Thomas, John T. O'Brien
Publikováno v:
Parkinsonism & Related Disorders. 101:111-116
INTRODUCTION: Amyloid-β (Aβ) deposition is common in dementia with Lewy bodies (DLB) and has been associated with more rapid disease progression. An effective biomarker that identified the presence of significant brain Aβ in people with DLB may be
Autor:
Nicola Barnett, Jim Lloyd, Paul C. Donaghy, George Petrides, Alan J. Thomas, John-Paul Taylor, Ian G. McKeith, Fiona E. Matthews, Calum A Hamilton, John T. O'Brien, Kirsty Olsen
Publikováno v:
The American Journal of Geriatric Psychiatry. 29:272-284
Objective We explored whether the mild cognitive impairment (MCI) stages of dementia with Lewy bodies (DLB) and Alzheimer disease (AD) differ in their cognitive profiles, and longitudinal progression. Design A prospective, longitudinal design was uti
Autor:
Paul C. Donaghy, Kirsty Olsen, Joanna Ciafone, Sally Barker, Calum A. Hamilton, John-Paul Taylor, Michael J. Firbank, Fiona E. Matthews, Nicola Barnett, Alan J. Thomas, Ian G. McKeith, Gemma Roberts, Rory Durcan, John T. O'Brien
Publikováno v:
Neurology
article-version (Version of Record) 3
article-version (Version of Record) 3
ObjectiveTo determine whether mild cognitive impairment with Lewy bodies or mild cognitive impairment with Alzheimer disease differ in their rates of clinical progression to dementia, we undertook longitudinal observation of mild cognitive impairment
Autor:
Rory Durcan, John T. O'Brien, Alan J. Thomas, Calum A Hamilton, Tamir Ali, Joanna Ciafone, Gemma Roberts, Michael J. Firbank, Sean J. Colloby, Kim Howe, John-Paul Taylor, Kirsty Olsen, Sally Barker, Louise Allan, Paul C. Donaghy, Sarah Lawley, Jim Lloyd, George Petrides, Nicola Barnett
Publikováno v:
The British Journal of Psychiatry. 218:276-282
BackgroundDopaminergic imaging is an established biomarker for dementia with Lewy bodies, but its diagnostic accuracy at the mild cognitive impairment (MCI) stage remains uncertain.AimsTo provide robust prospective evidence of the diagnostic accuracy
Autor:
Katrina, daSilva Morgan, Julia, Schumacher, Daniel, Collerton, Sean, Colloby, Greg J, Elder, Kirsty, Olsen, Dominic H, Ffytche, John-Paul, Taylor
Publikováno v:
Ophthalmology. 129(12)
To investigate the potential therapeutic benefits and tolerability of inhibitory transcranial direct current stimulation (tDCS) on the remediation of visual hallucinations in Charles Bonnet syndrome (CBS).Randomized, double-masked, placebo-controlled
Autor:
Nicola Barnett, Alan J. Thomas, John T. O'Brien, Kirsty Olsen, Paul C. Donaghy, Jim Lloyd, George Petrides, Michael J. Firbank
Publikováno v:
Parkinsonism & Related Disorders. 78:109-115
Introduction White matter disruption in dementia has been linked to a variety of factors including vascular disease and cortical pathology. We aimed to examine the relationship between white matter changes on diffusion tensor imaging (DTI) in DLB and
Autor:
Carmen Martin-Ruiz, John-Paul Taylor, John T. O'Brien, Kirsty Olsen, Alan J. Thomas, Calum A Hamilton, Paul C. Donaghy, Nicola Barnett, Christopher Morris
Publikováno v:
International Journal of Geriatric Psychiatry. 35:1250-1259
OBJECTIVES We conducted a prospective longitudinal study of plasma cytokines during the Mild Cognitive Impairment (MCI) stage of Lewy body disease and Alzheimer's disease, hypothesizing that cytokine levels would decrease over time and that this woul
Autor:
John-Paul Taylor, Fiona E. Matthews, Ian G. McKeith, Kirsty Olsen, John T. O'Brien, Paul C. Donaghy, Alan J. Thomas, Calum A Hamilton, Nicola Barnett
Publikováno v:
Psychological Medicine. 51:2590-2598
BackgroundMild cognitive impairment (MCI) may gradually worsen to dementia, but often remains stable for extended periods of time. Little is known about the predictors of decline to help explain this variation. We aimed to explore whether this hetero