Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Kirsty L, Brain"'
Autor:
Kirsty L Brain, Beth J Allison, Youguo Niu, Christine M Cross, Nozomi Itani, Andrew D Kane, Emilio A Herrera, Katie L Skeffington, Kimberley J Botting, Dino A Giussani
Publikováno v:
PLoS Biology, Vol 17, Iss 1, p e2006552 (2019)
Evidence derived from human clinical studies and experimental animal models shows a causal relationship between adverse pregnancy and increased cardiovascular disease in the adult offspring. However, translational studies isolating mechanisms to desi
Externí odkaz:
https://doaj.org/article/891649ff31054c8eac304daa17a68641
Autor:
Sandra Orgeig, Kirsty L. Brain, Andrew D. Kane, Erin V. McGillick, Emilio A. Herrera, Youguo Niu, Janna L. Morrison, Beth J. Allison, Katie L. Skeffington, Dino A. Giussani, Nozomi Itani
BACKGROUND: In the fetus, the appropriate balance of prooxidants and antioxidants is essential to negate the detrimental effects of oxidative stress on lung maturation. Antioxidants improve respiratory function in postnatal life and adulthood. Howeve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::869661be071e8a77236e0a79d7c86dc0
Autor:
Chritian Beck, Avnesh S. Thakor, Emilio A. Herrera, Nozomi Itani, Caroline J. Shaw, Katie L. Skeffington, Kirsty L. Brain, Dino A. Giussani, Kimberley J. Botting, Christine M. Cross, Andrew D. Kane, Youguo Niu, Beth J. Allison
Publikováno v:
Hypertension (Dallas, Tex. : 1979)
Supplemental Digital Content is available in the text.
The hypoxic fetus is at greater risk of cardiovascular demise during a challenge, but the reasons behind this are unknown. Clinically, progress has been hampered by the inability to study th
The hypoxic fetus is at greater risk of cardiovascular demise during a challenge, but the reasons behind this are unknown. Clinically, progress has been hampered by the inability to study th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::363056456a64391da2981abfb2db8233
https://pubmed.ncbi.nlm.nih.gov/32862711
https://pubmed.ncbi.nlm.nih.gov/32862711
Autor:
Michael P. Murphy, Nozomi Itani, Katie L. Skeffington, Youguo Niu, Christian Beck, Dino A. Giussani, A. J. Murray, Kimberley J. Botting, Beth J. Allison, Kirsty L. Brain, Angela Logan
Publikováno v:
Science Advances
Mitochondrial therapy may cure hypertension in adult offspring of complicated pregnancies.
The prenatal origins of heart disease in offspring have been established. However, research in species with developmental milestones comparable to humans
The prenatal origins of heart disease in offspring have been established. However, research in species with developmental milestones comparable to humans
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6487521f443f62beacf726332fa2b26
https://pubmed.ncbi.nlm.nih.gov/32875110
https://pubmed.ncbi.nlm.nih.gov/32875110
Autor:
Sandra Orgeig, Beth J. Allison, Andrew D. Kane, Emilio A. Herrera, Nozomi Itani, Erin V. McGillick, Kirsty L. Brain, Katie L. Skeffington, Dino A. Giussani, Janna L. Morrison, Youguo Niu
Publikováno v:
The Journal of Physiology. 595:4329-4350
British Heart Foundation / National Health and Medical Research Council (NHMRC), APP1030853 / NHMRC, APP1066916
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8895269612f7e600ab29825f06482aa1
https://doi.org/10.1113/jp273842
https://doi.org/10.1113/jp273842
Autor:
Beth J. Allison, Kirsty L. Brain, Youguo Niu, Kimberley J. Botting, Gail ter Haar, Ian Rivens, Dino A. Giussani, Christoph Lees, Caroline J. Shaw, John Civale
Publikováno v:
Journal of the Royal Society Interface
High-intensity focused ultrasound (HIFU) is a non-invasive method of selective placental vascular occlusion, providing a potential therapy for conditions such as twin–twin transfusion syndrome. In order to translate this technique into human studie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09875e1500da2caca82e9c0b9d529de1
https://pubmed.ncbi.nlm.nih.gov/31039691
https://pubmed.ncbi.nlm.nih.gov/31039691
Autor:
Beth J. Allison, Youguo Niu, Emilio A. Herrera, Joepe J. Kaandorp, Jan B. Derks, Andrew D. Kane, Jeremy A. Hansell, Kirsty L. Brain, Dino A. Giussani
Publikováno v:
The Journal of Physiology. 592:475-489
Hypoxia is a common challenge to the fetus, promoting a physiological defence to redistribute blood flow towards the brain and away from peripheral circulations. During acute hypoxia, reactive oxygen species (ROS) interact with nitric oxide (NO) to p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::91bdc03377b37d23ceb490af3e13d7fb
https://doi.org/10.1113/jphysiol.2013.264275
https://doi.org/10.1113/jphysiol.2013.264275
Autor:
Erin V, McGillick, Sandra, Orgeig, Beth J, Allison, Kirsty L, Brain, Youguo, Niu, Nozomi, Itani, Katie L, Skeffington, Andrew D, Kane, Emilio A, Herrera, Dino A, Giussani, Janna L, Morrison
Publikováno v:
The Journal of physiology. 595(13)
Chronic fetal hypoxaemia is a common pregnancy complication associated with intrauterine growth restriction that may influence respiratory outcome at birth. We investigated the effect of maternal chronic hypoxia for a month in late gestation on signa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1e2623ae3009bea17f46db079fd67892
https://pubmed.ncbi.nlm.nih.gov/28318025
https://pubmed.ncbi.nlm.nih.gov/28318025
Autor:
Dino A, Giussani, Youguo, Niu, Emilio A, Herrera, Hans G, Richter, Emily J, Camm, Avnesh S, Thakor, Andrew D, Kane, Jeremy A, Hansell, Kirsty L, Brain, Katie L, Skeffington, Nozomi, Itani, F B Peter, Wooding, Christine M, Cross, Beth J, Allison
Publikováno v:
Advances in experimental medicine and biology. 814
The quality of the intrauterine environment interacts with our genetic makeup to shape the risk of developing disease in later life. Fetal chronic hypoxia is a common complication of pregnancy. This chapter reviews how fetal chronic hypoxia programme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f920d0b36e6c1837285e9216c2d4e6af
https://pubmed.ncbi.nlm.nih.gov/25015802
https://pubmed.ncbi.nlm.nih.gov/25015802
Autor:
Andrew D, Kane, Jeremy A, Hansell, Emilio A, Herrera, Beth J, Allison, Youguo, Niu, Kirsty L, Brain, Joepe J, Kaandorp, Jan B, Derks, Dino A, Giussani
Publikováno v:
The Journal of physiology. 592(3)
Hypoxia is a common challenge to the fetus, promoting a physiological defence to redistribute blood flow towards the brain and away from peripheral circulations. During acute hypoxia, reactive oxygen species (ROS) interact with nitric oxide (NO) to p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::bae45a9ad061ef8bc7405c9331a1a9c4
https://pubmed.ncbi.nlm.nih.gov/24488071
https://pubmed.ncbi.nlm.nih.gov/24488071