Zobrazeno 1 - 10
of 94
pro vyhledávání: '"Kirsty G Pringle"'
Autor:
Joshua J Fisher, Tegan Grace, Nathan A Castles, Elizabeth A Jones, Sarah J Delforce, Alexandra E Peters, Gabrielle K Crombie, Emily C Hoedt, Kirby E Warren, Richard GS Kahl, Jonathan J Hirst, Kirsty G Pringle, Craig E Pennell
Publikováno v:
JMIR Research Protocols, Vol 13, p e63562 (2024)
BackgroundResearch in the developmental origins of health and disease provides compelling evidence that adverse events during the first 1000 days of life from conception can impact life course health. Despite many decades of research, we still lack a
Externí odkaz:
https://doaj.org/article/c68da455b506445d99fffdb18617d1b5
Autor:
Sarah J Delforce, Eugenie R Lumbers, Celine Corbisier de Meaultsart, Yu Wang, Anthony Proietto, Geoffrey Otton, Jim Scurry, Nicole M Verrills, Rodney J Scott, Kirsty G Pringle
Publikováno v:
Endocrine Connections, Vol 6, Iss 1, Pp 9-19 (2017)
A dysfunctional endometrial renin–angiotensin system (RAS) could aid the growth and spread of endometrial cancer. To determine if the RAS is altered in endometrial cancer, we measured RAS gene expression and protein levels in 30 human formalin-fixe
Externí odkaz:
https://doaj.org/article/42cfb83f6b9749d4b136457c8068f8df
Autor:
Kirsty G Pringle, Sarah J Delforce, Yu Wang, Katie A Ashton, Anthony Proietto, Geoffrey Otton, C Caroline Blackwell, Rodney J Scott, Eugenie R Lumbers
Publikováno v:
Endocrine Connections, Vol 5, Iss 3, Pp 1-8 (2016)
Endometrial cancer (EC) is the most common gynaecological malignancy and its incidence is increasing. Dysregulation of the endometrial renin–angiotensin system (RAS) could predispose to EC; therefore, we studied the prevalence of RAS single nucleot
Externí odkaz:
https://doaj.org/article/5a4c634f2c9c410094465843f82ece74
Autor:
Saije K. Morosin, Sarah J. Delforce, Celine Corbisier de Meaultsart, Eugenie R. Lumbers, Kirsty G. Pringle
Publikováno v:
Cell Death and Disease, Vol 12, Iss 7, Pp 1-7 (2021)
Abstract FURIN is a pro-protein convertase previously shown to be important for placental syncytialisation (Zhou et al. [1]), a process of cell fusion whereby placental cytotrophoblast cells fuse to form a multinucleated syncytium. This finding has b
Externí odkaz:
https://doaj.org/article/f8b96d60c7914dd08de38386ef1b01c2
Autor:
Richard J. Head, Eugenie R. Lumbers, Bevyn Jarrott, Felix Tretter, Gary Smith, Kirsty G. Pringle, Saiful Islam, Jennifer H. Martin
Publikováno v:
Pharmacology Research & Perspectives, Vol 10, Iss 1, Pp n/a-n/a (2022)
Abstract Why a systems analysis view of this pandemic? The current pandemic has inflicted almost unimaginable grief, sorrow, loss, and terror at a global scale. One of the great ironies with the COVID‐19 pandemic, particularly early on, is counter
Externí odkaz:
https://doaj.org/article/132b3f35d5f34085b479372eba541eac
Publikováno v:
Pharmacology Research & Perspectives, Vol 10, Iss 1, Pp n/a-n/a (2022)
Abstract Infection of humans with SARS‐CoV‐2 virus causes a disease known colloquially as “COVID‐19” with symptoms ranging from asymptomatic to severe pneumonia. Initial pathology is due to the virus binding to the ACE‐2 protein on endoth
Externí odkaz:
https://doaj.org/article/114570a35c2f498f8a50f59daeaf5591
Autor:
Eugenie R. Lumbers, Richard Head, Gary R. Smith, Sarah J. Delforce, Bevyn Jarrott, Jennifer H.Martin, Kirsty G. Pringle
Publikováno v:
Pharmacology Research & Perspectives, Vol 10, Iss 1, Pp n/a-n/a (2022)
Abstract SARS‐CoV‐2 interacting with its receptor, angiotensin‐converting enzyme 2 (ACE2), turns the host response to viral infection into a dysregulated uncontrolled inflammatory response. This is because ACE2 limits the production of the pept
Externí odkaz:
https://doaj.org/article/da485de05a3d4caea7d795e8b296e828
Autor:
Sonia Tamanna, Vicki L. Clifton, Kym Rae, Dirk F. van Helden, Eugenie R. Lumbers, Kirsty G. Pringle
Publikováno v:
Frontiers in Physiology, Vol 12 (2021)
Externí odkaz:
https://doaj.org/article/25cd18c61de740c8bdf93ce3a5773164
Autor:
Sonia Tamanna, Vicki L. Clifton, Kym Rae, Dirk F. van Helden, Eugenie R. Lumbers, Kirsty G. Pringle
Publikováno v:
Frontiers in Physiology, Vol 11 (2020)
IntroductionAn imbalance in angiotensin (Ang) peptides could contribute to the pathophysiology of preeclampsia (PE) and poor fetal growth.MethodsWe measured maternal plasma levels of Ang peptides and converting enzymes in non-pregnant women (n = 10),
Externí odkaz:
https://doaj.org/article/7a770936bd464895ae9a007a91dcbd98
Autor:
Jacinta H, Martin, Riazuddin, Mohammed, Sarah J, Delforce, David A, Skerrett-Byrne, Celine Corbisier, de Meaultsart, Juhura G, Almazi, Andrew N, Stephens, Nicole M, Verrills, Evdokia, Dimitriadis, Yu, Wang, Eugenie R, Lumbers, Kirsty G, Pringle
Publikováno v:
Oncotarget. 13:587-599
Endometrial cancer is the most diagnosed gynecological malignancy. Despite numerous scientific advances, the incidence and mortality rate of endometrial cancer continues to rise. Emerging evidence suggests a putative role of the (pro)renin receptor (