Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Kirsty F. Houslay"'
Autor:
Elizabeth England, D. Gareth Rees, Ian Christopher Scott, Sara Carmen, Denice T. Y. Chan, Catherine E. Chaillan Huntington, Kirsty F. Houslay, Teodor Erngren, Mark Penney, Jayesh B. Majithiya, Laura Rapley, Dorothy A. Sims, Claire Hollins, Elizabeth C. Hinchy, Martin D. Strain, Benjamin P. Kemp, Dominic J. Corkill, Richard D. May, Katherine A. Vousden, Robin J. Butler, Tomas Mustelin, Tristan J. Vaughan, David C. Lowe, Caroline Colley, E. Suzanne Cohen
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-15 (2023)
Abstract Interleukin (IL)-33 is a broad-acting alarmin cytokine that can drive inflammatory responses following tissue damage or infection and is a promising target for treatment of inflammatory disease. Here, we describe the identification of tozora
Externí odkaz:
https://doaj.org/article/4d1e1f2da3f148aa85e1df6a32f0ef69
Autor:
Elizabeth England, D. Gareth Rees, Ian Christopher Scott, Sara Carmen, Denice T. Y. Chan, Catherine E. Chaillan Huntington, Kirsty F. Houslay, Teodor Erngren, Mark Penney, Jayesh B. Majithiya, Laura Rapley, Dorothy A. Sims, Claire Hollins, Elizabeth C. Hinchy, Martin D. Strain, Benjamin P. Kemp, Dominic J. Corkill, Richard D. May, Katherine A. Vousden, Robin J. Butler, Tomas Mustelin, Tristan J. Vaughan, David C. Lowe, Caroline Colley, E. Suzanne Cohen
Interleukin (IL)-33 is a broad-acting alarmin cytokine that can drive inflammatory responses following tissue damage or infection and is a promising target for treatment of inflammatory disease. Here, we describe the identification of tozorakimab (ME
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2623b7a64721c16cead1782c6553f513
https://doi.org/10.1101/2023.02.28.527262
https://doi.org/10.1101/2023.02.28.527262
Autor:
Tsvetana Petrova, Manuel van Gijsel-Bonnello, Kirsty F. Houslay, J. Simon C. Arthur, Shaista Naqvi
IL-23 is an IL-12 family cytokine that is important in promoting Th17 responses and has been strongly linked to autoimmunity and psoriasis. It is a heterodimeric cytokine made up of a p19 subunit unique to IL-23 and a p40 subunit that is shared with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a369ae1a5d23825f4dce07083a2a20b2
https://doi.org/10.1101/2020.07.07.189142
https://doi.org/10.1101/2020.07.07.189142
Autor:
Frank Christian, George S. Baillie, Ruth MacLeod, David R. Adams, Miles D. Houslay, Kirsty F. Houslay
Publikováno v:
Biochemical Journal
Houslay, K, Christian, F, MacLeod, R, Adams, D, Houslay, M D & Baillie, G S 2017, ' Identification of a multifunctional docking site on the catalytic unit of phosphodiesterase-4 (PDE4) that is utilised by multiple interaction partners ', Biochemical Journal, vol. 474, no. 4, pp. 597-609 . https://doi.org/10.1042/BCJ20160849
Houslay, K, Christian, F, MacLeod, R, Adams, D, Houslay, M D & Baillie, G S 2017, ' Identification of a multifunctional docking site on the catalytic unit of phosphodiesterase-4 (PDE4) that is utilised by multiple interaction partners ', Biochemical Journal, vol. 474, no. 4, pp. 597-609 . https://doi.org/10.1042/BCJ20160849
Cyclic AMP (cAMP)-specific phosphodiesterase-4 (PDE4) enzymes underpin compartmentalised cAMP signalling by localising to distinct signalling complexes. PDE4 long isoforms can be phosphorylated by mitogen-activated protein kinase-activated protein ki
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::471b36512244c0b7b6f80a0058213440
https://eprints.gla.ac.uk/133060/7/133060.pdf
https://eprints.gla.ac.uk/133060/7/133060.pdf