Zobrazeno 1 - 10
of 88
pro vyhledávání: '"Kirsty A. Walters"'
Autor:
Ali Aflatounian, Valentina Rodriguez Paris, Dulama Richani, Melissa C. Edwards, Blake J. Cochran, William L. Ledger, Robert B. Gilchrist, Michael J. Bertoldo, Lindsay E. Wu, Kirsty A. Walters
Publikováno v:
Molecular Metabolism, Vol 65, Iss , Pp 101583- (2022)
Polycystic ovary syndrome (PCOS) is a common endocrine disorder, defined by reproductive and endocrine abnormalities, with metabolic dysregulation including obesity, insulin resistance and hepatic steatosis. Recently, it was found that skeletal muscl
Externí odkaz:
https://doaj.org/article/7efa99fc15fb4a50a22ad24541ad7e8e
Autor:
Valentina Rodriguez Paris, Samantha M. Solon-Biet, Alistair M. Senior, Melissa C. Edwards, Reena Desai, Nicodemus Tedla, Madeleine J. Cox, William L. Ledger, Robert B. Gilchrist, Stephen J. Simpson, David J. Handelsman, Kirsty A. Walters
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
Lifestyle interventions are first-line treatment for women with polycystic ovary syndrome (PCOS), but the optimal diet remains undefined. Here the authors identify an optimum dietary macronutrient balance that can rectify PCOS reproductive traits in
Externí odkaz:
https://doaj.org/article/3a5629219905422c9f942f689f72059f
Publikováno v:
Frontiers in Endocrinology, Vol 12 (2021)
BackgroundWhilst the ability of AMH to induce the regression of the Müllerian ducts in the male fetus is well appreciated, AMH has additional biological actions in relation to steroid biosynthesis and ovarian follicle dynamics. An understanding of t
Externí odkaz:
https://doaj.org/article/2c15d126e22f4db5ae672c78029d5ae2
Autor:
Irene E. SUCQUART, Ruchi NAGARKAR, Melissa C. EDWARDS, Valentina RODRIGUEZ PARIS, Ali AFLATOUNIAN, Michael J. BERTOLDO, Rebecca E. CAMPBELL, Denovan P. BEGG, David J. HANDELSMAN, Vasantha PADMANABHAN, Richard A. ANDERSON, Robert B. GILCHRIST, Kirsty A. WALTERS
Publikováno v:
Fertility & Reproduction, Vol 04, Iss 03n04, Pp 160-160 (2022)
Background: Polycystic ovary syndrome (PCOS) is a heterogeneous endocrine condition affecting up to 20% of reproductively aged women worldwide. Owing to an ambiguous etiology and complicated pathophysiology, current PCOS treatments remain purely symp
Externí odkaz:
https://doaj.org/article/ea7e67a813874cc585e156f6b3c1c55a
Autor:
Valentina RODRIGUEZ PARIS, Stephanie J. ALEXOPOULOS, Ying HU, Divya P. SHAH, Ali AFLATOUNIAN, Melissa C. EDWARDS, Michael J. BERTOLDO, Robert B. GILCHRIST, Kyle L. HOEHN, Kirsty A. WALTERS
Publikováno v:
Fertility & Reproduction, Vol 04, Iss 03n04, Pp 208-208 (2022)
Background: Polycystic ovary syndrome (PCOS) is a common endocrine condition characterized by endocrine, reproductive and metabolic abnormalities. There is no cure for PCOS and existing treatments are suboptimal. Obesity and adverse metabolic feature
Externí odkaz:
https://doaj.org/article/d923795257b04d2aaaed62399be9eef7
Autor:
Ting XIONG, Valentina RODRIGUEZ PARIS, Melissa C. EDWARDS, Blake J. COCHRAN, Kerry-Anne RYE, William L. LEDGER, Vasantha PADMANABHAN, David J. HANDELSMAN, Robert B. GILCHRIST, Kirsty A. WALTERS
Publikováno v:
Fertility & Reproduction, Vol 04, Iss 03n04, Pp 169-169 (2022)
Background: Polycystic ovary syndrome (PCOS) is a common disorder characterised by endocrine, reproductive and metabolic dysfunction. Hyperandrogenism is a key diagnostic trait and evidence supports a role for androgen receptor (AR) mediated actions
Externí odkaz:
https://doaj.org/article/f6cdf8c47318471b9ec7662235ac417c
Autor:
Genia F. Burchall, Dodie S. Pouniotis, Helena J. Teede, Sanjeeva Ranasinha, Kirsty A. Walters, Terrence J. Piva
Publikováno v:
Reproductive Biology and Endocrinology, Vol 17, Iss 1, Pp 1-14 (2019)
Abstract Background The fibrinolytic system and its inhibitors play a number of roles, apart from their function in blood haemostasis and thrombosis, namely in ovarian folliculogenesis and in ovulation. Plasminogen is converted to active plasmin at t
Externí odkaz:
https://doaj.org/article/8b313ef63e8b43e6b84b2c8d4ceaa6f6
Autor:
Michael J. Bertoldo, Dave R. Listijono, Wing-Hong Jonathan Ho, Angelique H. Riepsamen, Dale M. Goss, Dulama Richani, Xing L. Jin, Saabah Mahbub, Jared M. Campbell, Abbas Habibalahi, Wei-Guo Nicholas Loh, Neil A. Youngson, Jayanthi Maniam, Ashley S.A. Wong, Kaisa Selesniemi, Sonia Bustamante, Catherine Li, Yiqing Zhao, Maria B. Marinova, Lynn-Jee Kim, Laurin Lau, Rachael M. Wu, A. Stefanie Mikolaizak, Toshiyuki Araki, David G. Le Couteur, Nigel Turner, Margaret J. Morris, Kirsty A. Walters, Ewa Goldys, Christopher O’Neill, Robert B. Gilchrist, David A. Sinclair, Hayden A. Homer, Lindsay E. Wu
Publikováno v:
Cell Reports, Vol 30, Iss 6, Pp 1670-1681.e7 (2020)
Summary: Reproductive aging in female mammals is an irreversible process associated with declining oocyte quality, which is the rate-limiting factor to fertility. Here, we show that this loss of oocyte quality with age accompanies declining levels of
Externí odkaz:
https://doaj.org/article/a90efaf77b4241cf832c48855e659c9a
Autor:
Robert Gilchrist, Wing-Hong Jonathan Ho, Maria B Marinova, Dave R Listijono, Michael J Bertoldo, Dulama Richani, Kim Lynn-Jee, Amelia Brown, Angelique H Riepsamen, Safaa Cabot, Sonia Bustamante, Ling Zhong, Kaisa Selesniemi, Derek Wong, Dale M Goss, Catherine Li, Toshiyuki Araki, David J Livingston, Nigel Turner, David A Sinclair, Kirsty A Walters, Hayden A Homer, Lindsay E Wu
Publikováno v:
Fertility & Reproduction, Vol 05, Iss 04, Pp 518-518 (2023)
Background and Aims: Chemotherapy induced ovarian failure and infertility is an important concern in female cancer patients of reproductive age or younger, and non-invasive, pharmacological approaches to prevent chemotherapy induced infertility are u
Externí odkaz:
https://doaj.org/article/34e09bb2cf2c4adf92b3339f6ca9ecaf
Autor:
Valentina Rodriguez Paris, Xin Yi Denise Wong, Samantha M Solon-Biet, Melissa C Edwards, Ali Aflatounian, Robert B Gilchrist, Stephen J Simpson, David J Handelsman, Nadeem O Kaakoush, Kirsty A Walters
Publikováno v:
Gut Microbes, Vol 14, Iss 1 (2022)
The gut microbiome has been implicated in polycystic ovary syndrome (PCOS) pathophysiology. PCOS is a disorder with reproductive, endocrine and metabolic irregularities, and several studies report that PCOS is associated with a decrease in microbial
Externí odkaz:
https://doaj.org/article/b8726557763444eca5d070104fa8422e