Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Kirsty A. Green"'
Autor:
Ib Jarle Christensen, Leif R. Lund, Andreas Hald, Kasper Almholt, Boye Schnack Nielsen, Kirsty A. Green, Martin Illemann, John Rømer, Ida K. Lund, Birgitte Rønø
Publikováno v:
Developmental Biology; Vol 358
Urokinase-type plasminogen activator (uPA) and matrix metalloproteinase-9 (MMP9, gelatinase B) have separately been recognized to play important roles in various tissue remodeling processes. In this study, we demonstrate that deficiency for MMP9 in c
Publikováno v:
Developmental Biology. 299(1):164-175
The extracellular serine protease, plasmin, is activated from its precursor, plasminogen (Plg), by the urokinase-type and tissue-type Plg activators (uPA and tPA respectively). One of the main plasmin substrates, fibrin, is formed from fibrinogen via
Autor:
Kirsty A. Green, Charles H. Streuli
Publikováno v:
Cellular and Molecular Life Sciences. 61:1867-1883
Epithelial apoptosis has a key role in the development and function of the mammary gland. It is involved with the formation of ducts during puberty and is required to remove excess epithelial cells after lactation so that the gland can be prepared fo
Autor:
Leif R. Lund, Kasper Almholt, Kirsty A. Green, Anna Juncker-Jensen, Helene Solberg, John Romer
Publikováno v:
The Cancer Degradome ISBN: 9780387690568
Plasminogen (Plg) is perhaps the most abundant and widely distributed protease zymogen in the organism. The local activation of Plg by the highly specific Plg activators is involved in a number of processes that require proteolytic restructuring of t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0d5db13ecd077e74044da89a3bdd7ab2
https://doi.org/10.1007/978-0-387-69057-5_11
https://doi.org/10.1007/978-0-387-69057-5_11
Autor:
Emma Marshman, Matthew J. Naylor, Charles H. Streuli, Pengbo Wang, Kirsty A. Green, Emma T. Lowe
Publikováno v:
The Journal of biological chemistry. 279(24)
Apoptosis is an important mechanism for maintaining tissue homeostasis. The efficient induction and execution of apoptosis are essential for cell clearance in specific developmental situations. Insulin-like growth factor (IGF)-I is a survival factor
Autor:
Leif R. Lund, Kirsty A. Green, Boye Schnack Nielsen, Anna Juncker-Jensen, John Rømer, Kasper Almholt
Publikováno v:
Journal of Mammary Gland Biology and Neoplasia
Growth and invasion of breast cancer require extracellular proteolysis in order to physically restructure the tissue microenvironment of the mammary gland. This pathological tissue remodeling process depends on a collaboration of epithelial and strom
Autor:
Kasper Almholt, Thomas H. Bugge, Francis J. Castellino, Birgitte Rønø, Michael Ploug, Morten Johnsen, Leif R. Lund, John Rømer, Kirsty A. Green
Publikováno v:
Journal of Investigative Dermatology. (8):2092-2101
Genetic ablation of plasminogen (Plg) and pharmacological inhibition of metalloproteinase activity by galardin delay skin wound healing in mice, whereas the combined inhibition of these two enzyme systems completely prevents healing. In this study, t