Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Kirston Barton"'
Autor:
Nasir Riaz, Preston Leung, Kirston Barton, Martin A. Smith, Shaun Carswell, Rowena Bull, Andrew R. Lloyd, Chaturaka Rodrigo
Publikováno v:
BMC Genomics, Vol 22, Iss 1, Pp 1-12 (2021)
Abstract Background Hepatitis C (HCV) and many other RNA viruses exist as rapidly mutating quasi-species populations in a single infected host. High throughput characterization of full genome, within-host variants is still not possible despite advanc
Externí odkaz:
https://doaj.org/article/27ac5a45c50a4b9891f2a9cec58eaa4c
Autor:
Qian Du, Grady C. Smith, Phuc Loi Luu, James M. Ferguson, Nicola J. Armstrong, C. Elizabeth Caldon, Elyssa M. Campbell, Shalima S. Nair, Elena Zotenko, Cathryn M. Gould, Michael Buckley, Kee-Ming Chia, Neil Portman, Elgene Lim, Dominik Kaczorowski, Chia-Ling Chan, Kirston Barton, Ira W. Deveson, Martin A. Smith, Joseph E. Powell, Ksenia Skvortsova, Clare Stirzaker, Joanna Achinger-Kawecka, Susan J. Clark
Publikováno v:
Cell Reports, Vol 36, Iss 12, Pp 109722- (2021)
Summary: DNA replication timing and three-dimensional (3D) genome organization are associated with distinct epigenome patterns across large domains. However, whether alterations in the epigenome, in particular cancer-related DNA hypomethylation, affe
Externí odkaz:
https://doaj.org/article/a960e9f898d54e74a0e23ec3aac378c2
Autor:
Mark A. Corbett, Thessa Kroes, Liana Veneziano, Mark F. Bennett, Rahel Florian, Amy L. Schneider, Antonietta Coppola, Laura Licchetta, Silvana Franceschetti, Antonio Suppa, Aaron Wenger, Davide Mei, Manuela Pendziwiat, Sabine Kaya, Massimo Delledonne, Rachel Straussberg, Luciano Xumerle, Brigid Regan, Douglas Crompton, Anne-Fleur van Rootselaar, Anthony Correll, Rachael Catford, Francesca Bisulli, Shreyasee Chakraborty, Sara Baldassari, Paolo Tinuper, Kirston Barton, Shaun Carswell, Martin Smith, Alfredo Berardelli, Renee Carroll, Alison Gardner, Kathryn L. Friend, Ilan Blatt, Michele Iacomino, Carlo Di Bonaventura, Salvatore Striano, Julien Buratti, Boris Keren, Caroline Nava, Sylvie Forlani, Gabrielle Rudolf, Edouard Hirsch, Eric Leguern, Pierre Labauge, Simona Balestrini, Josemir W. Sander, Zaid Afawi, Ingo Helbig, Hiroyuki Ishiura, Shoji Tsuji, Sanjay M. Sisodiya, Giorgio Casari, Lynette G. Sadleir, Riaan van Coller, Marina A. J. Tijssen, Karl Martin Klein, Arn M. J. M. van den Maagdenberg, Federico Zara, Renzo Guerrini, Samuel F. Berkovic, Tommaso Pippucci, Laura Canafoglia, Melanie Bahlo, Pasquale Striano, Ingrid E. Scheffer, Francesco Brancati, Christel Depienne, Jozef Gecz
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-10 (2019)
Familial cortical myoclonic tremor (FAME) has so far been mapped to regions on chromosome 2, 3, 5 and 8 and pentameric repeat expansions in SAMD12 were identified as cause of FAME1. Here, Corbett et al. identify ATTTT/ATTTC repeat expansions in intro
Externí odkaz:
https://doaj.org/article/752a22f841ae41c284ab977e7ffdeead
Autor:
Mandeep Singh, Ghamdan Al-Eryani, Shaun Carswell, James M. Ferguson, James Blackburn, Kirston Barton, Daniel Roden, Fabio Luciani, Tri Giang Phan, Simon Junankar, Katherine Jackson, Christopher C. Goodnow, Martin A. Smith, Alexander Swarbrick
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
Single cell RNA sequencing generates short reads from one end of a template, providing incomplete transcript coverage and limiting identification of diverse sequences such as antigen receptors. Here the authors combine long read nanopore sequencing w
Externí odkaz:
https://doaj.org/article/c60a66377d0242a7a325fe287cec34d3
Autor:
Bonnie Hiener, Bethany A. Horsburgh, John-Sebastian Eden, Kirston Barton, Timothy E. Schlub, Eunok Lee, Susanne von Stockenstrom, Lina Odevall, Jeffrey M. Milush, Teri Liegler, Elizabeth Sinclair, Rebecca Hoh, Eli A. Boritz, Daniel Douek, Rémi Fromentin, Nicolas Chomont, Steven G. Deeks, Frederick M. Hecht, Sarah Palmer
Publikováno v:
Cell Reports, Vol 21, Iss 3, Pp 813-822 (2017)
Latent replication-competent HIV-1 persists in individuals on long-term antiretroviral therapy (ART). We developed the Full-Length Individual Proviral Sequencing (FLIPS) assay to determine the distribution of latent replication-competent HIV-1 within
Externí odkaz:
https://doaj.org/article/873ec4da1964441691d787de3e0ab81b
Autor:
Simon A. Hardwick, Samuel D. Bassett, Dominik Kaczorowski, James Blackburn, Kirston Barton, Nenad Bartonicek, Shaun L. Carswell, Hagen U. Tilgner, Clement Loy, Glenda Halliday, Tim R. Mercer, Martin A. Smith, John S. Mattick
Publikováno v:
Frontiers in Genetics, Vol 10 (2019)
The human brain is one of the last frontiers of biomedical research. Genome-wide association studies (GWAS) have succeeded in identifying thousands of haplotype blocks associated with a range of neuropsychiatric traits, including disorders such as sc
Externí odkaz:
https://doaj.org/article/1e92fdf57727448c8d717531c35b6024
Autor:
Kirston Barton, Bonnie Hiener, Anni Winckelmann, Thomas Aagaard Rasmussen, Wei Shao, Karen Byth, Robert Lanfear, Ajantha Solomon, James McMahon, Sean Harrington, Maria Buzon, Mathias Lichterfeld, Paul W. Denton, Rikke Olesen, Lars Østergaard, Martin Tolstrup, Sharon R. Lewin, Ole Schmeltz Søgaard, Sarah Palmer
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-8 (2016)
Treatment of HIV-1 infected patients with latency-reversing agents (LRA) induces transcription of proviruses in CD4 T cells. Using single-genome sequencing, the authors show that the LRA-induced CD4 T cell-associated HIV RNA is genetically diverse an
Externí odkaz:
https://doaj.org/article/07b5827ef392461e8e435aa6680c0e9b
Autor:
Hao-Wen Sim, Kirston Barton, Zarnie Lwin, Jonathon Parkinson, Neda Haghighi, Elizabeth Hovey, Robyn Leonard, Hui K Gan, Benjamin Y. Kong, Mustafa Khasraw, Matthew Foote, David S. Ziegler, Anna K. Nowak, Candace Carter
Publikováno v:
Asia-Pacific Journal of Clinical Oncology. 18:259-266
Aim The neuro-oncology community in Australia is well positioned to collaborate internationally, with a motivated trials group, strong regulatory bodies and an attractive fiscal environment. We sought to identify gaps in the Australian neuro-oncology
Autor:
Shaun Carswell, Chaturaka Rodrigo, Preston Leung, Rowena A. Bull, Martin A. Smith, Andrew R. Lloyd, Nasir Riaz, Kirston Barton
Publikováno v:
BMC Genomics, Vol 22, Iss 1, Pp 1-12 (2021)
BMC Genomics
BMC Genomics
Background Hepatitis C (HCV) and many other RNA viruses exist as rapidly mutating quasi-species populations in a single infected host. High throughput characterization of full genome, within-host variants is still not possible despite advances in nex
Autor:
Thiruni N. Adikari, Vanessa W X Lim, Praveen Weeratunga, Senaka Rajapakse, Deepika Fernando, Katja Fink, Braulio M. Valencia, Nasir Riaz, Andrew R. Lloyd, Martin A. Smith, Preston Leung, Rowena A. Bull, Tun-Linn Thein, Chathurani Sigera, Fabio Luciani, Chaturaka Rodrigo, Yee Sin Leo, Hui Li, Kirston Barton
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)
Scientific Reports
Scientific Reports
Current methods for dengue virus (DENV) genome amplification, amplify parts of the genome in at least 5 overlapping segments and then combine the output to characterize a full genome. This process is laborious, costly and requires at least 10 primers