Zobrazeno 1 - 10
of 104
pro vyhledávání: '"Kirstine, Calloe"'
Autor:
Kirstine Calloe, Helena B. D. Magnusson, Dorte Launholt Lildballe, Morten Krogh Christiansen, Henrik Kjærulf Jensen
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 10 (2023)
In the past 20 years, genetic variants in SCN5A encoding the cardiac voltage-gated sodium channel Nav1.5 have been linked to a range of inherited cardiac arrhythmias: variants resulting in loss-of-function of Nav1.5 have been linked to sick sinus syn
Externí odkaz:
https://doaj.org/article/a3d25884c9f0402595254de4a76f5f7a
Autor:
Sarah Spruce Preisler, Anders Drabaek Wiuf, Marc Friis, Lasse Kjaergaard, Molly Hurd, Eva Ramos Becares, Casper Normann Nurup, Frederik Bühring Bjoerkskov, Zsófia Szathmáry, Pontus Emanuel Gourdon, Kirstine Calloe, Dan A. Klaerke, Kamil Gotfryd, Per Amstrup Pedersen
Publikováno v:
Current Research in Structural Biology, Vol 3, Iss , Pp 51-71 (2021)
Integral membrane proteins (IMPs) constitute ~30% of all proteins encoded by the genome of any organism and Escherichia coli remains the first-choice host for recombinant production of prokaryotic IMPs. However, the expression levels of prokaryotic I
Externí odkaz:
https://doaj.org/article/78e6030e5b5d476d87a45b56829272e3
Autor:
Nora Linscheid, Alberto Santos, Pi Camilla Poulsen, Robert W Mills, Kirstine Calloe, Ulrike Leurs, Johan Z Ye, Christian Stolte, Morten B Thomsen, Bo H Bentzen, Pia R Lundegaard, Morten S Olesen, Lars J Jensen, Jesper V Olsen, Alicia Lundby
Publikováno v:
PLoS Biology, Vol 19, Iss 4, p e3001144 (2021)
Delineating human cardiac pathologies and their basic molecular mechanisms relies on research conducted in model organisms. Yet translating findings from preclinical models to humans present a significant challenge, in part due to differences in card
Externí odkaz:
https://doaj.org/article/803278d7d2314c97a5198af5d5449f9c
Autor:
Tina V A Hansen, Susanna Cirera, Cédric Neveu, Elise Courtot, Claude L Charvet, Kirstine Calloe, Dan A Klaerke, Richard J Martin
Publikováno v:
PLoS Pathogens, Vol 17, Iss 2, p e1008982 (2021)
In the absence of efficient alternative strategies, the control of parasitic nematodes, impacting human and animal health, mainly relies on the use of broad-spectrum anthelmintic compounds. Unfortunately, most of these drugs have a limited single-dos
Externí odkaz:
https://doaj.org/article/6f32684346f64814837de8a794333bf3
Patient iPSC-Derived Neurons for Disease Modeling of Frontotemporal Dementia with Mutation in CHMP2B
Autor:
Yu Zhang, Benjamin Schmid, Nanett K. Nikolaisen, Mikkel A. Rasmussen, Blanca I. Aldana, Mikkel Agger, Kirstine Calloe, Tina C. Stummann, Hjalte M. Larsen, Troels T. Nielsen, Jinrong Huang, Fengping Xu, Xin Liu, Lars Bolund, Morten Meyer, Lasse K. Bak, Helle S. Waagepetersen, Yonglun Luo, Jørgen E. Nielsen, Bjørn Holst, Christian Clausen, Poul Hyttel, Kristine K. Freude
Publikováno v:
Stem Cell Reports, Vol 8, Iss 3, Pp 648-658 (2017)
The truncated mutant form of the charged multivesicular body protein 2B (CHMP2B) is causative for frontotemporal dementia linked to chromosome 3 (FTD3). CHMP2B is a constituent of the endosomal sorting complex required for transport (ESCRT) and, when
Externí odkaz:
https://doaj.org/article/ddcff1aabf094e94bc737b7fbb9ee240
Autor:
Kirstine Calloe, Michelle Geryk, Kristine Freude, Jacqueline A Treat, Victoria A Vold, Henriette Reventlow S Frederiksen, Anders Krogh Broendberg, Tanja Charlotte Frederiksen, Henrik K Jensen, Jonathan M Cordeiro
Publikováno v:
Calloe, K, Geryk, M, Freude, K, Treat, J A, Vold, V A, Frederiksen, H R S, Broendberg, A K, Frederiksen, T C, Jensen, H K & Cordeiro, J M 2022, ' The G213D variant in Nav1.5 alters sodium current and causes an arrhythmogenic phenotype resulting in a multifocal ectopic Purkinje-related premature contraction phenotype in human-induced pluripotent stem cell-derived cardiomyocytes ', Europace, vol. 24, no. 12, pp. 2015–2027 . https://doi.org/10.1093/europace/euac090
Aims Variants in SCN5A encoding Nav1.5 are associated with cardiac arrhythmias. We aimed to determine the mechanism by which c.638G>A in SCNA5 resulting in p.Gly213Asp (G213D) in Nav1.5 altered Na+ channel function and how flecainide corrected the de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85b744baf01ac9143dffcf92964a0a7d
https://doi.org/10.1093/europace/euac090
https://doi.org/10.1093/europace/euac090
Autor:
Kaituo Wang, Sarah Spruce Preisler, Liying Zhang, Yanxiang Cui, Julie Winkel Missel, Christina Grønberg, Kamil Gotfryd, Erik Lindahl, Magnus Andersson, Kirstine Calloe, Pascal F Egea, Dan Arne Klaerke, Michael Pusch, Per Amstrup Pedersen, Z Hong Zhou, Pontus Gourdon
Publikováno v:
PLoS Biology, Vol 17, Iss 4, p e3000218 (2019)
ClC-1 protein channels facilitate rapid passage of chloride ions across cellular membranes, thereby orchestrating skeletal muscle excitability. Malfunction of ClC-1 is associated with myotonia congenita, a disease impairing muscle relaxation. Here, w
Externí odkaz:
https://doaj.org/article/83a7e6f4ff29469c8e807f5e8caa11cf
Autor:
Sara Hougaard Pedersen, Sanne Hage la Cour, Kirstine Calloe, Frank Hauser, Jes Olesen, Dan Arne Klaerke, Inger Jansen-Olesen
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 13 (2019)
Infusion of pituitary adenylate cyclase activating peptide-38 (PACAP-38) provokes migraine attacks in migraineurs and headache in non-migraineurs. Adverse events like long-lasting flushing and heat sensation can be terminated with oral antihistamine
Externí odkaz:
https://doaj.org/article/5634e5ff694c489c8c70913927a207d2
Autor:
Muhammad Tayyib Naseem, Robin Beaven, Takashi Koyama, Sehrish Naz, Mooney Su, David P. Leader, Dan Klærke, Kirstine Calloe, Barry Denholm, Kenneth Veland Halberg
Publikováno v:
Naseem, M T, Beaven, R, Koyama, T, Naz, S, Su, S-Y, Leader, D P, A Klaerke, D, Calloe, K, Denholm, B & Halberg, K V 2023, ' NHA1 is a cation/proton antiporter essential for the water-conserving functions of the rectal complex in Tribolium castaneum . ', Proceedings of the National Academy of Sciences of the United States of America, vol. 120, no. 13, e2217084120 . https://doi.org/10.1073/pnas.2217084120
More than half of all extant metazoan species on earth are insects. The evolutionary success of insects is intrinsically linked with their ability to osmoregulate, suggesting that they have evolved unique physiological mechanisms to maintain water ba
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d76d9027df1e57b063df83e2f9db9952
https://doi.org/10.1073/pnas.2217084120
https://doi.org/10.1073/pnas.2217084120
Autor:
Vibeke S. Elbrønd, Morten B. Thomsen, Jonas L. Isaksen, Ester D. Lunde, Stefano Vincenti, Tobias Wang, Jørgen Tranum‐Jensen, Kirstine Calloe
Publikováno v:
Elbrønd, V S, Thomsen, M B, Isaksen, J L, Lunde, E D, Vincenti, S, Wang, T, Tranum-Jensen, J & Calloe, K 2023, ' Intramural Purkinje fibers facilitate rapid ventricular activation in the equine heart ', Acta Physiologica, vol. 237, no. 3, e13925 . https://doi.org/10.1111/apha.13925
UNLABELLED: The Purkinje fibers convey the electrical impulses at much higher speed than the working myocardial cells. Thus, the distribution of the Purkinje network is of paramount importance for the timing and coordination of ventricular activation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a545f2a49beb9028eb8435105c6a183
https://curis.ku.dk/portal/da/publications/intramural-purkinje-fibers-facilitate-rapid-ventricular-activation-in-the-equine-heart(0610ed6d-dc8d-45cd-8436-454e366800d9).html
https://curis.ku.dk/portal/da/publications/intramural-purkinje-fibers-facilitate-rapid-ventricular-activation-in-the-equine-heart(0610ed6d-dc8d-45cd-8436-454e366800d9).html
