Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Kirstin Winkler-Stuck"'
Autor:
Falk R. Wiedemann, Elmar Kirches, Claus-W. Wallesch, C. Mawrin, Kirstin Winkler-Stuck, Wolfram S. Kunz, Hartmut Lins, Knut Dietzmann
Publikováno v:
Journal of Neural Transmission. 112:499-518
The origin and tissue distribution of the mitochondrial dysfunction in Parkinson's disease (PD) remains still a matter of controversy. To re-evaluate a probably free radical-born, generalized mitochondrial impairment in PD, we applied optimized enzym
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7412957232407a51e9dfde0c078a56bc
https://doi.org/10.1007/s00702-004-0195-y
https://doi.org/10.1007/s00702-004-0195-y
Publikováno v:
Journal of the Neurological Sciences. 220:41-48
Several lines of evidence suggest an impairment of mitochondrial function in the brain of patients with Parkinson's disease (PD). However, the presence of a detectable mitochondrial defect in extracerebral tissue of these patients remains a matter of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2bb68ace511bdacaf604fa4333e24fbe
https://doi.org/10.1016/j.jns.2004.02.003
https://doi.org/10.1016/j.jns.2004.02.003
Autor:
Iqbal Sayeed, Peter Schönfeld, Isabelle Trieu, Detlef Siemen, Suhel Parvez, Kirstin Winkler-Stuck, Claus-Werner Wallesch, Gordon Seitz
Publikováno v:
The FASEB Journal. 20:556-558
The dopamine-D2-agonist pramipexole (PPX) was tested for blocking mitochondrial permeability transition (PT) in order to give a possible explanation for its neuroprotective effect seen in PPX-treated Parkinson's disease patients. Patch-clamp techniqu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b59a9db70b6f86ad357fec89bb43c123
https://doi.org/10.1096/fj.05-4748fje
https://doi.org/10.1096/fj.05-4748fje
Publikováno v:
Clinical neuropathology. 26(4)
UNLABELLED The pathogenesis of the selective loss of dopaminergic neurons in idiopathic Parkinson's disease (PD) has not been understood up to now. Respiratory chain dysfunction and accumulation of mitochondrial DNA deletions to biochemically relevan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1a5fee4f14d2f05eeb51ca439f63b7b
https://pubmed.ncbi.nlm.nih.gov/17702497
https://pubmed.ncbi.nlm.nih.gov/17702497
Autor:
Schoeler S, Kathrin Chamaon, Elmar Kirches, M.F. Haroon, R. Szibor, F.N. Gellerich, C. Mawrin, Kirstin Winkler-Stuck
Publikováno v:
Neurobiology of Disease, Vol 25, Iss 3, Pp 536-544 (2007)
The mechanism of retinal ganglion cell loss in Leber's hereditary optic neuropathy (LHON) is still uncertain, and a role of enhanced superoxide production by the mutant mitochondrial complex I has been hypothesized. In the present study, it was shown
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7663c3894286223e5e3ac8d096542624
https://pubmed.ncbi.nlm.nih.gov/17169568
https://pubmed.ncbi.nlm.nih.gov/17169568
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Bioenergetics. :77
Ropinirole, an agonist of the post-synaptic dopamine D2-receptor, exerts neuroprotective activity. The mechanism is still under discussion. Assuming that this neuroprotection might be associated with inhibition of the apoptotic cascade underlying cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25475113cb839dc644678c76d5d4c1b4