Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Kirstin B. VanderWall"'
Autor:
Kang-Chieh Huang, Cátia Gomes, Yukihiro Shiga, Nicolas Belforte, Kirstin B. VanderWall, Sailee S. Lavekar, Clarisse M. Fligor, Jade Harkin, Shelby M. Hetzer, Shruti V. Patil, Adriana Di Polo, Jason S. Meyer
Publikováno v:
Acta Neuropathologica Communications, Vol 12, Iss 1, Pp 1-22 (2024)
Abstract The ability to derive retinal ganglion cells (RGCs) from human pluripotent stem cells (hPSCs) has led to numerous advances in the field of retinal research, with great potential for the use of hPSC-derived RGCs for studies of human retinal d
Externí odkaz:
https://doaj.org/article/35e2ff994a3b45f6abf25b65705e90fc
Autor:
Kirstin B. VanderWall, Ridhima Vij, Sarah K. Ohlemacher, Akshayalakshmi Sridhar, Clarisse M. Fligor, Elyse M. Feder, Michael C. Edler, Anthony J. Baucum, II, Theodore R. Cummins, Jason S. Meyer
Publikováno v:
Stem Cell Reports, Vol 12, Iss 2, Pp 201-212 (2019)
Summary: Retinal ganglion cells (RGCs) form the connection between the eye and the brain, with this connectivity disrupted in numerous blinding disorders. Previous studies have demonstrated the ability to derive RGCs from human pluripotent stem cells
Externí odkaz:
https://doaj.org/article/32b7f9cd1ac54eed97d9fd2c68d2ebbd
Autor:
Cátia Gomes, Kirstin B. VanderWall, Yanling Pan, Xiaoyu Lu, Sailee S. Lavekar, Kang-Chieh Huang, Clarisse M. Fligor, Jade Harkin, Chi Zhang, Theodore R. Cummins, Jason S. Meyer
Publikováno v:
Stem Cell Reports. 17:1636-1649
Although the degeneration of retinal ganglion cells (RGCs) is a primary characteristic of glaucoma, astrocytes also contribute to their neurodegeneration in disease states. Although studies often explore cell-autonomous aspects of RGC neurodegenerati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::597a180ddd017de54483c846cee0261a
https://doi.org/10.1016/j.stemcr.2022.05.006
https://doi.org/10.1016/j.stemcr.2022.05.006
Autor:
Kang-Chieh Huang, Cátia Gomes, Yukihiro Shiga, Nicolas Belforte, Kirstin B. VanderWall, Sailee S. Lavekar, Clarisse M. Fligor, Jade Harkin, Adriana Di Polo, Jason S. Meyer
Autophagy dysfunction has been associated with several neurodegenerative diseases including glaucoma, characterized by the degeneration of retinal ganglion cells (RGCs). However, the mechanisms by which autophagy dysfunction promotes RGC damage remai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3178c710022f73c5afb17ec353643cf8
https://doi.org/10.1101/2023.01.04.522687
https://doi.org/10.1101/2023.01.04.522687
Autor:
Kirsten Deprey, Nefeli Batistatou, Marjoke F. Debets, Jack Godfrey, Kirstin B. VanderWall, Rebecca R. Miles, Livia Shehaj, Jiaxing Guo, Amy Andreucci, Pachamuthu Kandasamy, Genliang Lu, Mamoru Shimizu, Chandra Vargeese, Joshua A. Kritzer
Publikováno v:
ACS Chem Biol
A major obstacle to the development of effective oligonucleotide therapeutics is a lack of understanding about their cytosolic and nuclear penetration. To address this problem, we have applied the chloroalkane penetration assay (CAPA) to oligonucleot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ca7a1a52699e0b7e5fa1b2efc41faf6
https://europepmc.org/articles/PMC9252293/
https://europepmc.org/articles/PMC9252293/
Autor:
Elyse M. Feder, Akshayalakshmi Sridhar, Michael C. Edler, Theodore R. Cummins, Anthony J. Baucum, Clarisse M. Fligor, Sarah K. Ohlemacher, Ridhima Vij, Kirstin B. VanderWall, Jason S. Meyer
Publikováno v:
Stem Cell Reports, Vol 12, Iss 2, Pp 201-212 (2019)
Stem Cell Reports
Stem Cell Reports
Summary Retinal ganglion cells (RGCs) form the connection between the eye and the brain, with this connectivity disrupted in numerous blinding disorders. Previous studies have demonstrated the ability to derive RGCs from human pluripotent stem cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38d41e83afdecd72b51a53ab8b3b59bd
https://doi.org/10.1016/j.stemcr.2018.12.010
https://doi.org/10.1016/j.stemcr.2018.12.010
Autor:
Kirstin B. VanderWall, Jason S. Meyer, Sailee S. Lavekar, Kang-Chieh Huang, Priya K. Shields, Jade Harkin, Catia Gomes, Clarisse M. Fligor
Publikováno v:
Stem Cell Reports
Summary The development of the visual system involves the coordination of spatial and temporal events to specify the organization of varied cell types, including the elongation of axons from retinal ganglion cells (RGCs) to post-synaptic targets in t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::354314c77e967b4df32fecfd771ff82e
https://pubmed.ncbi.nlm.nih.gov/34115986
https://pubmed.ncbi.nlm.nih.gov/34115986
Autor:
Anna R. Allsop, Shaomei Wang, Kirstin B. VanderWall, Jorge S. Alfaro, Jason S. Meyer, Alexa S. Carr, Bin Lu
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-10 (2020)
Scientific Reports
Scientific Reports
Retinal ganglion cells (RGCs) are a heterogeneous population of neurons, comprised of numerous subtypes that work synchronously to transmit visual information to the brain. In blinding disorders such as glaucoma, RGCs are the main cell type to degene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec0e5b82fd8d475ff98c5195dcc978fb
https://doi.org/10.1038/s41598-020-71460-6
https://doi.org/10.1038/s41598-020-71460-6
Autor:
Clarisse M, Fligor, Kang-Chieh, Huang, Sailee S, Lavekar, Kirstin B, VanderWall, Jason S, Meyer
Publikováno v:
Methods in cell biology. 159
Human pluripotent stem cells (hPSCs) possess the remarkable ability to differentiate into any cell type of the body, including those of the retina. Through the differentiation of these cells as retinal organoids, it is now possible to model the spati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::54c95e6b0d9921fa6772cc7d425ff03c
https://pubmed.ncbi.nlm.nih.gov/32586447
https://pubmed.ncbi.nlm.nih.gov/32586447
Autor:
Kirstin B. VanderWall, Sailee S. Lavekar, Jason S. Meyer, Kang-Chieh Huang, Clarisse M. Fligor
Publikováno v:
Methods in Cell Biology ISBN: 9780128215319
Human pluripotent stem cells (hPSCs) possess the remarkable ability to differentiate into any cell type of the body, including those of the retina. Through the differentiation of these cells as retinal organoids, it is now possible to model the spati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8ec43a5dca4dfa4866ccace8ae5f8852
https://doi.org/10.1016/bs.mcb.2020.02.005
https://doi.org/10.1016/bs.mcb.2020.02.005