Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Kirstie M Bertram"'
Autor:
Freja A Warner van Dijk, Orion Tong, Thomas R O'Neil, Kirstie M Bertram, Kevin Hu, Heeva Baharlou, Erica E Vine, Kate Jenns, Martijn P Gosselink, James W Toh, Tim Papadopoulos, Laith Barnouti, Gregory J Jenkins, Gavin Sandercoe, Muzlifah Haniffa, Kerrie J Sandgren, Andrew N Harman, Anthony L Cunningham, Najla Nasr
Publikováno v:
PLoS Pathogens, Vol 20, Iss 6, p e1012351 (2024)
AXL+ Siglec-6+ dendritic cells (ASDC) are novel myeloid DCs which can be subdivided into CD11c+ and CD123+ expressing subsets. We showed for the first time that these two ASDC subsets are present in inflamed human anogenital tissues where HIV transmi
Externí odkaz:
https://doaj.org/article/1e4028ffe06646b1b34da8e1a361e6ce
Autor:
Kirstie M Bertram, Naomi R Truong, Jacinta B Smith, Min Kim, Kerrie J Sandgren, Konrad L Feng, Jason J Herbert, Hafsa Rana, Kevin Danastas, Monica Miranda-Saksena, Jake W Rhodes, Ellis Patrick, Ralph C Cohen, Jake Lim, Steven L Merten, Andrew N Harman, Anthony L Cunningham
Publikováno v:
PLoS Pathogens, Vol 17, Iss 4, p e1009536 (2021)
Skin mononuclear phagocytes (MNPs) provide the first interactions of invading viruses with the immune system. In addition to Langerhans cells (LCs), we recently described a second epidermal MNP population, Epi-cDC2s, in human anogenital epidermis tha
Externí odkaz:
https://doaj.org/article/16caffee82494e02a8f58ec3e503dd35
Autor:
Min Kim, Naomi R Truong, Virginia James, Lidija Bosnjak, Kerrie J Sandgren, Andrew N Harman, Najla Nasr, Kirstie M Bertram, Norman Olbourne, Shailandra Sawleshwarkar, Kaylene McKinnon, Ralph C Cohen, Anthony L Cunningham
Publikováno v:
PLoS Pathogens, Vol 11, Iss 4, p e1004812 (2015)
The mechanism by which immunity to Herpes Simplex Virus (HSV) is initiated is not completely defined. HSV initially infects mucosal epidermis prior to entering nerve endings. In mice, epidermal Langerhans cells (LCs) are the first dendritic cells (DC
Externí odkaz:
https://doaj.org/article/8a32ecd0291f47b8abe578e5c7de8e83
Autor:
Jake W. Rhodes, Rachel A. Botting, Kirstie M. Bertram, Erica E. Vine, Hafsa Rana, Heeva Baharlou, Peter Vegh, Thomas R. O’Neil, Anneliese S. Ashhurst, James Fletcher, Grant P. Parnell, J. Dinny Graham, Najla Nasr, Jake J. K. Lim, Laith Barnouti, Peter Haertsch, Martijn P. Gosselink, Angelina Di Re, Faizur Reza, Grahame Ctercteko, Gregory J. Jenkins, Andrew J. Brooks, Ellis Patrick, Scott N. Byrne, Eric Hunter, Muzlifah A. Haniffa, Anthony L. Cunningham, Andrew N. Harman
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Epithelial tissue mononuclear phagocytes (MNP) can transmit HIV to CD4 T cells, but less is known about sub-epithelial cells. Here, the authors describe MNPs in human anogenital and colorectal tissues and find that CD14+CD1c+ monocyte-derived dendrit
Externí odkaz:
https://doaj.org/article/3840bd9c9273487999b88e2c53427e0d
Autor:
Kirstie M. Bertram, Rachel A. Botting, Heeva Baharlou, Jake W. Rhodes, Hafsa Rana, J. Dinny Graham, Ellis Patrick, James Fletcher, Toby M. Plasto, Naomi R. Truong, Caroline Royle, Chloe M. Doyle, Orion Tong, Najla Nasr, Laith Barnouti, Mark P. Kohout, Andrew J. Brooks, Michael P. Wines, Peter Haertsch, Jake Lim, Martijn P. Gosselink, Grahame Ctercteko, Jacob D. Estes, Melissa J. Churchill, Paul U. Cameron, Eric Hunter, Muzlifah A. Haniffa, Anthony L. Cunningham, Andrew N. Harman
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
Composition and function of immune populations at barrier surfaces is crucial for response to infection. Here, the authors identify a population of dendritic cells in human epidermis, abundant in anogenital epithelia and distinct from Langerhans cell
Externí odkaz:
https://doaj.org/article/eb12f23a92dd489b8e91e926a319cbf1
Autor:
Erica E. Vine, Jake W. Rhodes, Freja A. Warner van Dijk, Scott N. Byrne, Kirstie M. Bertram, Anthony L. Cunningham, Andrew N. Harman
Publikováno v:
Mucosal Immunology. 15:542-550
Autor:
Kirstie M. Bertram, Thomas R. O’Neil, Erica E. Vine, Heeva Baharlou, Anthony L. Cunningham, Andrew N. Harman
Publikováno v:
Immunity. 56:459-460
Autor:
Heeva Baharlou, Nicolas Canete, Erica E Vine, Kevin Hu, Di Yuan, Kerrie J Sandgren, Kirstie M Bertram, Najla Nasr, Jake W Rhodes, Martijn P Gosselink, Angelina Di Re, Faizur Reza, Grahame Ctercteko, Nimalan Pathma-Nathan, Geoff Collins, James Toh, Ellis Patrick, Muzlifah A Haniffa, Jacob D. Estes, Scott N Byrne, Anthony L Cunningham, Andrew N Harman
The initial immune response to HIV is critical in determining transmission. However, due to technical limitations we still do not have a comparative map of early mucosal transmission events. We combined RNAscope, cyclic-immunofluorescence and novel i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::793443bdfcf0dce16336722e036197c4
https://doi.org/10.1101/2022.04.30.490175
https://doi.org/10.1101/2022.04.30.490175
Autor:
Erica E, Vine, Jake W, Rhodes, Freja A, Warner van Dijk, Scott N, Byrne, Kirstie M, Bertram, Anthony L, Cunningham, Andrew N, Harman
Publikováno v:
Mucosal immunology. 15(4)
In tissue, mononuclear phagocytes (MNP) are comprised of Langerhans cells, dendritic cells, macrophages and monocyte-derived cells. They are the first immune cells to encounter HIV during transmission and transmit the virus to CD4 T cells as a conseq
Autor:
Chloe M. Doyle, Nicole L. Fewings, Grahame Ctercteko, Scott N. Byrne, Andrew N. Harman, Kirstie M. Bertram
Publikováno v:
Cytometry. Part A : the journal of the International Society for Analytical CytologyREFERENCES. 101(3)
We developed a 25-color flow cytometry panel to comprehensively interrogate innate lymphoid cells (ILC), mucosal-associated invariant T (MAIT) cells, natural killer (NK) cells and γδ T cells in human tissues. The ability to isolate and interrogate