Heart Angiotensin-Converting Enzyme and Angiotensin-Converting Enzyme 2 Gene Expression Associated With Male Sex and Salt-Sensitive Hypertension in the Dahl Rat

Autor: Kirsti Ytrehus, Stian Ludvigsen, Costantino Mancusi, Eva Gerdts, Giovanni de Simone

Publikováno v: Frontiers in Physiology, Vol 12 (2021)

Angiotensin-converting enzyme 2 (ACE 2) in the heart including its sex dependency in the hypertensive heart, has not been much studied compared to ACE. In the present study, we used the Dahl salt-sensitive rat exposed to fructose and salt to model a

Externí odkaz: https://doaj.org/article/887c3c6c02d3450594aedff1f656feef

The acute phase of experimental cardiogenic shock is counteracted by microcirculatory and mitochondrial adaptations.

Autor: Thor Allan Stenberg, Anders Benjamin Kildal, Espen Sanden, Ole-Jakob How, Martin Hagve, Kirsti Ytrehus, Terje S Larsen, Truls Myrmel

Publikováno v: PLoS ONE, Vol 9, Iss 9, p e105213 (2014)

The mechanisms contributing to multiorgan dysfunction during cardiogenic shock are poorly understood. Our goal was to characterize the microcirculatory and mitochondrial responses following ≥ 10 hours of severe left ventricular failure and cardioge

Externí odkaz: https://doaj.org/article/52ccedf3ba9d4c7eb0f081924e3da0bc

Effect of transverse aortic constriction on cardiac structure, function and gene expression in pregnant rats.

Autor: Nils Thomas Songstad, David Johansen, Ole-Jacob How, Per Ivar Kaaresen, Kirsti Ytrehus, Ganesh Acharya

Publikováno v: PLoS ONE, Vol 9, Iss 2, p e89559 (2014)

BACKGROUND: There is an increased risk of heart failure and pulmonary edema in pregnancies complicated by hypertensive disorders. However, in a previous study we found that pregnancy protects against fibrosis and preserves angiogenesis in a rat model

Externí odkaz: https://doaj.org/article/74b304a145e64e81810519a24c4b4970

Impact of Maturation on Myocardial Response to Ischemia and the Effectiveness of Remote Preconditioning in Male Rats

Autor: Lucia Kindernay, Jaroslav Hrdlička, Kirsti Ytrehus, Tanya Ravingerova, Veronika Farkasova, Jan Neckar

Publikováno v: International Journal of Molecular Sciences, Vol 22, Iss 11009, p 11009 (2021)
International Journal of Molecular Sciences
Volume 22
Issue 20

Aging attenuates cardiac tolerance to ischemia/reperfusion (I/R) associated with defects in protective cell signaling, however, the onset of this phenotype has not been completely investigated. This study aimed to compare changes in response to I/R a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97fbc1634352647992b9da2650f75d6e
https://www.mdpi.com/1422-0067/22/20/11009

ESC Working Group on Cellular Biology of the Heart: position paper for Cardiovascular Research: tissue engineering strategies combined with cell therapies for cardiac repair in ischaemic heart disease and heart failure

Autor: Fabrice Prunier, Péter Ferdinandy, Joost P.G. Sluijter, Sandrine Lecour, Sophie Van Linthout, Linda W. van Laake, Maurizio Pesce, Hans Erik Bøtker, Kirsti Ytrehus, Sean M. Davidson, Felix B. Engel, Rosalinda Madonna, Francesco Fernandez-Aviles, Raffaele De Caterina, Cinzia Perrino, Philippe Menasché, Derek J. Hausenloy, Thomas Eschenhagen, Wolfram-Hubertus Zimmermann, Jonathan Leor, Jean-Sébastien Hulot

Publikováno v: Cardiovascular Research

Morbidity and mortality from ischaemic heart disease (IHD) and heart failure (HF) remain significant in Europe and are increasing worldwide. Patients with IHD or HF might benefit from novel therapeutic strategies, such as cell-based therapies. We rec

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5ae0d5cb209cfdafad3983912e9fce1
https://doi.org/10.1093/cvr/cvz010