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of 2
pro vyhledávání: '"Kirsten Ward-Hartstonge"'
Autor:
Ju Hee Oh, Rachel A. Cederberg, Erin Tanaka, Luisa Bopp, Terri Ser, Sara Niyyati, Annette E. Patterson, Neeku Amanat, Jared Dutra, Patricia Ye, Meredith Clark, Kirsten Ward-Hartstonge, Anne-Sophie Archambault, Janice Tsui, Philipp F. Lange, Sue Tsai, C. Bruce Verchere, Yongjin Park, Mario Fabri, Kevin L. Bennewith, Ramon I. Klein Geltink
SUMMARYCancer immunotherapy using antigen-specific CD8+T cells depends on long-lasting anti-tumor function of thein vitroexpanded T cells. T cell function is intricately linked to the activity of many metabolic pathways directly impacting the ability
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::68149a6a6b235701ee417ad837236baf
https://doi.org/10.1101/2023.03.27.533229
https://doi.org/10.1101/2023.03.27.533229
Autor:
Caroline Lamarche, Kirsten Ward-Hartstonge, Tian Mi, David T. S. Lin, Qing Huang, Andrew Brown, Karlie Edwards, Gherman E. Novakovsky, Christopher N. Qi, Michael S. Kobor, Caitlin C. Zebley, Evan W. Weber, Crystal L. Mackall, Megan K Levings
Publikováno v:
Proceedings of the National Academy of Sciences. 120
Regulatory T cell (Treg) therapy is a promising approach to improve outcomes in transplantation and autoimmunity. In conventional T cell therapy, chronic stimulation can result in poor in vivo function, a phenomenon termed exhaustion. Whether or not