Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Kirsten Remmert"'
Autor:
Ikuko Fujiwara, Thomas B. Friedman, Ya-Xian Wang, John A. Hammer, Ronald S. Petralia, Kirsten Remmert, Melanie Barzik, Christopher J. Alexander
Publikováno v:
FASEB J
Myosin 18Aα is a myosin 2-like protein containing unique N- and C-terminal protein interaction domains that co-assembles with myosin 2. One protein known to bind to myosin 18Aα is β-Pix, a guanine nucleotide exchange factor (GEF) for Rac1 and Cdc4
Autor:
Thomas B. Friedman, Ya-Xian Wang, John A. Hammer, Ikuko Fujiwara, Christopher J. Alexander, Melanie Barzik, Ronald S. Petralia, Kirsten Remmert
Dendritic spines are signaling microcompartments that serve as the primary site of synapse formation in neurons. Actin assembly and myosin 2 contractility play major roles in the maturation of spines from filopodial precursors, as well as in the subs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::125d31cdcfb6a836d9aa09b08d604e97
https://doi.org/10.1101/2020.02.12.944488
https://doi.org/10.1101/2020.02.12.944488
Autor:
Jordan R. Beach, John A. Hammer, James R. Sellers, Kirsten Remmert, Sarah M. Heissler, Kyle Bruun
Publikováno v:
Cytoskeleton. 74:205-218
The peri-centrosomal localization and morphology of the Golgi apparatus depends largely on the microtubule cytoskeleton and the microtubule motor protein dynein. Recent studies proposed that myosin 18Aα (M18Aα) also contributes to Golgi morphology
Autor:
Yingfan Zhang, Kyle Bruun, Nasser M. Rusan, Jordan R. Beach, Lin Shao, Eric Betzig, Mary Anne Conti, Zac Swider, Robert S. Adelstein, Dong Li, John A. Hammer, Kirsten Remmert
Publikováno v:
Nature cell biology
The cellular mechanisms governing non-muscle myosin II (NM2) filament assembly are largely unknown. Using EGFP-NM2A knock-in fibroblasts and multiple super-resolution imaging modalities, we characterized and quantified the sequential amplification of
Abstract C44: MBD3 stabilizes MYC, leading to metastatic outgrowth of pancreatic cancer in the liver
Autor:
Jonathan M. Hernandez, Reed I. Ayabe, Surajit Sinha, Shreya Gupta, James D. McDonald, Kirsten Remmert, Alok Ranjan, Imani Alexander, Michael M. Wach, Samantha M. Ruff
Publikováno v:
Cancer Research. 79:C44-C44
Introduction: Pancreatic cancer remains a challenging disease, with an overall cumulative 5-year survival rate less than 5%. Metastases are responsible for over 90% of cancer-related deaths. Despite significant progress made in cancer drug developmen
Autor:
Alok Ranjan, James D. McDonald, Imani Alexander, Jonathan M. Hernandez, Reed I. Ayabe, Michael M. Wach, Shreya Gupta, Elke Van Beek, Eileen Li, Kirsten Remmert, Samantha M. Ruff, Surajit Sinha
Publikováno v:
Cancer Research. 79:A50-A50
Introduction: Although liver metastasis is the major cause of pancreatic cancer mortality, the mechanisms by which KRAS-driven pancreatic tumor cells initiate metastatic outgrowth in the liver are unknown. High-throughput next-generation sequencing s
Publikováno v:
Current Biology. 24:1160-1166
Janelia Farm Research Campus, Howard Hughes MedicalInstitute, Ashburn, VA 20147, USASummaryNonmuscle myosin II (NM II) powers myriad developmentaland cellular processes, including embryogenesis, cellmigration, and cytokinesis [1]. To exert its functi
Autor:
Surajit Sinha, Jonathan Hernandez, Reed Ayabe, Michael Wach, Samantha Ruff, Alok Ranjan, Kirsten Remmert, Imani Alexander
Publikováno v:
Cancer Research. 79:3749-3749
Introduction: Disseminated tumor cells in the circulation upon extravasation into a secondary organ like the liver encounter hostile conditions like nutrient deprivation and oxidative stress and may undergo dormancy or growth arrest. The molecular dr
Autor:
Jonathan M. Hernandez, A.H. Ahn, Surajit Sinha, Reed I. Ayabe, William R. Jarnagin, Samantha M. Ruff, E. van Beek, Alok Ranjan, Michael M. Wach, Kirsten Remmert, Linda Bojmar
Publikováno v:
HPB. 21:S4
Publikováno v:
Journal of Biological Chemistry. 285:5738-5747
Programs exist for searching protein sequences for potential membrane-penetrating segments (hydrophobic regions) and for lipid-binding sites with highly defined tertiary structures, such as PH, FERM, C2, ENTH, and other domains. However, a rapidly gr