Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Kirsten Prüfer"'
Liver X receptor β with mutations in the activation function-2 region is excluded from the nucleolus
Publikováno v:
Cell Biology International. 33:447-452
Liver X receptors (LXRs) alpha and beta are ligand-induced transcription factors that regulate transcription of genes encoding key regulators of cholesterol metabolism and transport, and of lipogenesis. Despite their high similarity, LXRalpha is the
Autor:
Kirsten Prüfer, Jeanne Boudreaux
Publikováno v:
Journal of Cellular Biochemistry. 100:69-85
Activity of nuclear receptors is regulated by their nuclear localization. Liver X receptors (LXR) alpha and beta are nuclear receptors that regulate transcription of genes for cholesterol metabolism, cholesterol transport, and lipogenesis. While LXR
Autor:
Julia Barsony, Kirsten Prüfer
Publikováno v:
Molecular Endocrinology. 16:1738-1751
Liganded and unliganded vitamin D receptors (VDRs) carry out distinct functions; both types of functions require heterodimerization with retinoid X receptors (RXRs). Our recent studies with fluorescent protein chimeras of VDR and RXR, termed GFP-VDR,
Publikováno v:
Molecular Endocrinology. 16:961-976
Several cell lines, including ROS17/2.8 rat osteosarcoma (ROS) cells, contain functional VDRs and RXRs but are resistant to the antiproliferative effects of calcitriol and retinoids. We explored the role of receptor degradation in this hormone resist
Autor:
Gérard Labourdette, Dominique Baas, Sarlieve Ll, Marie Elisabeth Ittel, Sabine Kuchler-Bopp, Philippe Brachet, Kirsten Prüfer
Publikováno v:
Glia. 31:59-68
The present study investigates the presence of vitamin D receptor (VDR) in cells of the rat oligodendrocyte (OL) lineage. VDR transcripts were detected by in situ hybridization in a fraction of rat OL in secondary cultures. The VDR protein was shown
Publikováno v:
Cellular and Molecular Neurobiology. 19:613-624
1.The rat olfactory system contains numerous target sites for 1,25-dihydroxyvitamin D3, as determined by receptor protein (VDR) immunocytochemistry and in situ hybidization. 2.Nuclear and cytoplasmic VDR immunoreactivity as well as the corresponding
Autor:
Gustav F. Jirikowski, Kirsten Prüfer
Publikováno v:
Biochemical Pharmacology. 51:247-252
1.25-dihydroxyvitamin D3 is of clinical importance (e.g. in the treatment of psoriasis) given its ability to regulate the proliferation and differentiation of human keratinocytes. 1.25-Dihydroxyvitamin D3 mediates its action via genomic and nongenomi
Autor:
Hideo Uno, E. Marttin, Kenneth J. McGinley, Nelly Boehm, A. Barth, Berhard Schaaf, Brunhilde Knöll, Nava Dayan, Danielle Chateau, Sotaro Kurata, Fabrice Pirot, Arlene N. Foglia, J. Huschenbeck, D. Müller, Hans Törmä, Arun B. Barua, P. Humbert, F.H.N. De Haan, Benjamin R. Vowels, M.T.A. Neelissen-Subnel, Charles N. Gropper, Julie E. Wahrman, Harry E. Boddé, Hans F. Merck, Kirsten Prüfer, Brigitte Samama, Jean-Marie Geiger, F. Panisset, James J. Leyden, Eva Stenström, Uwe Wollina, Anders Vahlquist, P. Agache, Francesca Levi-Schaffer, Carina Björklind, Lynn Allen-Hoffmann, David R. Bickers, Elka Touitou, James Allen Olson
Publikováno v:
Skin Pharmacology and Physiology. 9:78-92
Publikováno v:
Europe PubMed Central
Comparative testing of seven wound dressings (WD) has been performed with human HaCaT keratinocyte and mouse 3T3 fibroblast cultures. To assess biocompatibility, morphologic examinations were combined with cell counting. Supernatants were subjected t
Publikováno v:
The international journal of biochemistrycell biology. 41(4)
Liver X receptors (LXRs) alpha and beta are nuclear receptors, which form obligate heterodimers with the retinoid X receptor (RXR). The LXRs regulate both redundantly and non-redundantly the transcription of genes controlling cholesterol metabolism a