Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Kirsten M. Carlson"'
Autor:
Marco A. S. Baptista, Kuldip D. Dave, Niketa P. Sheth, Shehan N. De Silva, Kirsten M. Carlson, Yasmin N. Aziz, Brian K. Fiske, Todd B. Sherer, Mark A. Frasier
Publikováno v:
Disease Models & Mechanisms, Vol 6, Iss 6, Pp 1316-1324 (2013)
Progress in Parkinson’s disease (PD) research and therapeutic development is hindered by many challenges, including a need for robust preclinical animal models. Limited availability of these tools is due to technical hurdles, patent issues, licensi
Externí odkaz:
https://doaj.org/article/303759b3808c4f2a93495588bcc24a37
Publikováno v:
Neuroscience Letters. 489:1-4
We wished to determine whether L-DOPA, a common treatment for the motor deficits in Parkinson's disease, could also reverse the motor deficits that occur during aging. We assessed motor performance in young (2-3 months) and old (20-21 months) male C5
Autor:
Huan Ngo, Sean Scott, Eugene M. Johnson, Mike Sasner, Brian H. Johnstone, Anatoly Chernyshev, Yun Li, Ben A. Barres, Jennifer R. Gatchel, Cat Lutz, Greg Cox, Patrizia Fanara, Tennore Ramesh, Kirsten M. Carlson, Steve Perrin, Nico Stanculescu, Jonathan D. Glass, Gabrielle Strobel, Stanley H. Appel, Jeyanthi Ramasubbu, Melanie L. Leitner
Publikováno v:
Journal of Alzheimer's Disease. 16:197-205
Publikováno v:
Journal of Neuroscience Research. 86:2039-2049
Glial cell line-derived neurotrophic factor (GDNF) has been shown to be neuroprotective in animal models of the dopamine deficiency in Parkinson's disease. To examine the role of the extracellular signal-regulated kinases 1 and 2 (ERK1/2) in this pro
Autor:
Kirsten M. Carlson, George C. Wagner
Publikováno v:
Behavioural Pharmacology. 17:475-484
Exercise exerts neuroprotective effects and facilitates neural recovery in animal models of Parkinson's disease. In the present studies, effects of exercise on amphetamine-induced dopaminergic toxicity were assessed in mice housed individually either
Autor:
Yao-Ping Lu, Kirsten M. Carlson, Laura Michna, Jian-Guo Xie, Qing-Yun Peng, Allan H. Conney, You-Rong Lou, Yong Lin, George C. Wagner, Weichung Joe Shih
Publikováno v:
Carcinogenesis. 27:2108-2115
Earlier studies showed that oral administration of green tea or caffeine to SKH-1 mice inhibited ultraviolet B light (UVB)-induced skin carcinogenesis, decreased dermal fat thickness and increased locomotor activity. In the present study, the effects
Autor:
Kirsten M. Carlson, George C. Wagner
Publikováno v:
Brain Research. 1087:186-189
The effect of tail shock (ten, 2.0 mA/0.15 s shocks) on amphetamine-induced dopaminergic toxicity in adult, male BALB/c mice was assessed. Fifteen minutes following a single shock session, mice received amphetamine (50-mg/kg) or saline as follows: Sh
Autor:
George C. Wagner, Kirsten M. Carlson
Publikováno v:
Life Sciences. 77:372-385
The effects of phencyclidine on an operant task were evaluated prior to and after neurotoxic lesions of the striatum in rats. Subjects were trained to respond on a fixed-interval 90-second schedule for water presentation. The degree to which phencycl
Publikováno v:
Life Sciences. 73:311-317
The effects of acute administration of nicotine on target biting (defensive) and resident-intruder (offensive) attack of male mice were assessed. In the target biting procedure confined mice received tail shock on a fixed time, 2-min schedule. Under
Publikováno v:
Parkinsonism & Related Disorders. 16:S11