Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Kirsten M Leu"'
Autor:
Howard Streicher, Elad Sharon, Razelle Kurzrock, Young Kwang Chae, Megan Othus, Edward Mayerson, Melissa Plets, Charles Blanke, Ashish Sangal, Benjamin Powers, Chung-Tsen Hsueh, Rashmi Chugh, Suresh Nair, Mark Agulnik, G Thomas Budd, Michael J Wagner, Sandip P Patel, Chris Ryan, Adrienne I Victor, Kirsten M Leu
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 8 (2021)
Purpose Angiosarcoma is a rare aggressive endothelial cell cancer with high mortality. Isolated reports suggest immune checkpoint inhibition efficacy in angiosarcoma, but no prospective studies have been published. We report results for angiosarcoma
Externí odkaz:
https://doaj.org/article/ad13fb519e1d42b98dad31e0b713b156
Autor:
Jonathan C. Trent, Andrew E. Rosenberg, Andrea P. Espejo-Freire, Andrew Elliott, Don S. Dizon, Margaret von Mehren, Ty K. Subhawong, Julio A. Diaz-Perez, Daniel Magee, Emily Jonczak, Junaid Arshad, William M. Korn, A. Hussein, Matthew J. Oberley, Priscila Barreto-Coelho, Philippos Apolinario Costa, Gina Z. D'Amato, Kirsten M. Leu, Moh’d M. Khushman
Publikováno v:
Cancers
Cancers; Volume 13; Issue 19; Pages: 4816
Cancers, Vol 13, Iss 4816, p 4816 (2021)
Cancers; Volume 13; Issue 19; Pages: 4816
Cancers, Vol 13, Iss 4816, p 4816 (2021)
Simple Summary Angiosarcomas (AS) are rare, highly aggressive sarcomas with limited therapeutic options. Genomic sequencing techniques have identified recurrent genetic abnormalities. Nevertheless, the association of these findings with etiology, sit
Autor:
Scott M. Schuetze, Laurence H. Baker, Daniel A. Rushing, Rashmi Chugh, Margaret von Mehren, Warren Chow, Kirsten M. Leu, Vanessa Bolejack, David R. Lucas, David M. Loeb, Mohammed M. Milhem, Shreyaskumar Patel, Denise K. Reinke, Brian L. Samuels, Hussein Abdul-Hassan Tawbi, Gina Z. D'Amato, Edwin Choy, Kristen N. Ganjoo, Arthur P. Staddon, Charles Forscher
Publikováno v:
Cancer. 123:90-97
BACKGROUND Alveolar soft part sarcoma (ASPS), chondrosarcoma (CS), chordoma, epithelioid sarcoma, and solitary fibrous tumor (SFT) are malignant tumors that are relatively resistant to chemotherapy and for which more effective drug therapy is needed.
Autor:
Laurence H. Baker, Mark M. Zalupski, Rashmi Chugh, Joseph R. Mace, Rodney L. Dunn, Vernon K. Sondak, Kirsten M. Leu, J. Sybil Biermann, William F. Chandler
Publikováno v:
Journal of Clinical Oncology. 23:3597-3604
Purpose The purpose of this trial was to assess the objective clinical response, toxicity, and time to progression of treatment with 9-Nitro-Camptothecin (9-NC) in patients with advanced chordoma, soft tissue sarcoma (STS), and gastrointestinal strom
Autor:
Mark M. Zalupski, Kirsten M. Leu, Laurence H. Baker, Kent A. Griffith, T. Wagner, Francis P. Worden, Dafydd G. Thomas, Jeremy M. G. Taylor, Rashmi Chugh
Publikováno v:
Cancer. 109(11)
BACKGROUND. Ifosfamide is a chemotherapeutic agent that requires cytochrome P450 3A (CYP3A) for bioactivation and metabolism. To the authors' knowledge, the correlation between dose, pharmacokinetics, CYP3A, and toxicity has not been fully evaluated.
Autor:
Laurence H. Baker, Dafydd G. Thomas, J. Sybil Biermann, Thomas J. Giordano, Hassan R. Dhaini, Kirsten M. Leu, Timothy D. Johnson, Paul F. Hollenberg
Publikováno v:
Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 21(13)
Purpose: Osteosarcoma, the most common pediatric primary bone tumor, is an aggressive malignancy with a tendency for early pulmonary metastasis. A reliable biomarker to predict clinical outcome at diagnosis has not yet been identified. To date, patho
Autor:
Kirsten M, Leu, Gregory P, Kalemkerian
Publikováno v:
The New England journal of medicine. 347(5)
Publikováno v:
Lung cancer (Amsterdam, Netherlands). 34(1)
We conducted a phase I/II trial of the combination of docetaxel and weekly vinorelbine in patients with stage IIIB or IV non-small cell lung cancer (NSCLC) who were refractory or resistant to platinum-based regimens. The objectives of the study were
Autor:
Gregory P. Kalemkerian, Kirsten M. Leu
Publikováno v:
New England Journal of Medicine. 347:e2