Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Kirsten M Hooper"'
Autor:
Kate M. Rahbari, Weimin Kong, Ana M. Gamero, Kirsten M. Hooper, Doina Ganea, Ping-Chang Kuo, Jui-Hung Yen
Publikováno v:
The Journal of Immunology. 198:1521-1530
IL-27, a multifunctional cytokine produced by APCs, antagonizes inflammation by affecting conventional dendritic cells (cDC), inducing IL-10, and promoting development of regulatory Tr1 cells. Although the mechanisms involved in IL-27 induction are w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7108c51395098b6896d7491453c78606
https://doi.org/10.4049/jimmunol.1601073
https://doi.org/10.4049/jimmunol.1601073
Autor:
Roberto Caricchio, Paul M. Gallo, Doina Ganea, Kirsten M. Hooper, Michael H. Lee, Chelsea Corradetti, Stefania Gallucci
Publikováno v:
J Leukoc Biol
IL-10 is elevated in the autoimmune disease systemic lupus erythematosus (SLE). Here, we show that conventional dendritic cells (cDCs) from predisease lupus-prone B6.NZM Sle1/Sle2/Sle3 triple congenic (TCSle) mice produce more IL-10 than wild-type co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e223163d98b3b14f664d81aec6d02cab
https://pubmed.ncbi.nlm.nih.gov/31216373
https://pubmed.ncbi.nlm.nih.gov/31216373
Publikováno v:
Acta Physiologica. 213:442-452
Neuropeptides represent an important category of endogenous contributors to the establishment and maintenance of immune deviation in the immune-privileged organs such as the CNS and in the control of acute inflammation in the peripheral immune organs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f98185225fd5d6bde2cb5cc84d490f4f
https://doi.org/10.1111/apha.12427
https://doi.org/10.1111/apha.12427
Autor:
Mireia Uribe-Herranz, Liselotte E. Jensen, Katelynn A. Milora, Li-Hua Lian, Kirsten M. Hooper
Publikováno v:
The Journal of investigative dermatology
Munro’s microabscesses contain polymorphonuclear leukocytes and form specifically in the epidermis of psoriasis patients. The mechanism whereby the neutrophils are recruited into the epidermis is poorly understood. Using a combination of human and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::349f5a5247635b77ffc0ac13949da6bd
Publikováno v:
PLoS ONE, Vol 12, Iss 6, p e0179184 (2017)
PLoS ONE
PLoS ONE
Prostaglandin E2 (PGE2), a major lipid mediator abundant at inflammatory sites, acts as a proinflammatory agent in models of inflammatory/autoimmune diseases by promoting CD4 Th1/Th17 differentiation. Regulatory T cells, including the IL-10 producing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3453c63a18ce448acbeba6ad9ef7c4e0
http://europepmc.org/articles/PMC5467903?pdf=render
http://europepmc.org/articles/PMC5467903?pdf=render
Publikováno v:
Brain, behavior, and immunity. 53
Prostaglandins and leukotrienes, bioactive mediators generated by cyclooxygenases (COX) and 5-lipoxygenase (5-LO) from arachidonic acid, play an essential role in neuroinflammation. High levels of LTB4 and PGE2 and increased expression of COX and 5-L
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b592118f0a0dda980b5a633c46d952e
https://pubmed.ncbi.nlm.nih.gov/26541818
https://pubmed.ncbi.nlm.nih.gov/26541818
Autor:
Sami Sauma, D. Craig Hooper, Michael Prosniak, Mélanie Morin-Brureau, Kirsten M. Hooper, David W. Andrews, Larry Harshyne
Publikováno v:
Cancer Immunology, Immunotherapy
Cancer Immunology, Immunotherapy, 2015, 64 (4), pp.447-457. ⟨10.1007/s00262-015-1654-z⟩
Cancer Immunology, Immunotherapy, 2015, 64 (4), pp.447-457. ⟨10.1007/s00262-015-1654-z⟩
International audience; lymphocytes. Overnight treatment with NOBEL in vitro reduces IGF-1R expression by GL261 cells but has minimal effect on cell viability and does not reduce the capacity of the cells to form tumors upon implantation. In contrast
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87d1facd76fc31827c7c76981a4e1e56
https://hal.sorbonne-universite.fr/hal-03997649
https://hal.sorbonne-universite.fr/hal-03997649
Autor:
Weimin Kong, Ping-Chang Kuo, Frances A. Emig, Jui-Hung Yen, Kirsten M. Hooper, Doina Ganea, Kate M. Rahbari, Barbara A. Scofield
Publikováno v:
Journal of leukocyte biology. 98(5)
MS is an autoimmune disease characterized by immune cell infiltration in the CNS, leading to cumulative disability. IFN-β, used clinically in RR-MS reduces lesion formation and rates of relapse. Although the molecular mechanisms are not entirely elu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::058c927f691e7a7ea75232e44dd134e9
https://pubmed.ncbi.nlm.nih.gov/26525842
https://pubmed.ncbi.nlm.nih.gov/26525842
Autor:
Brian J. Nasca, D. Craig Hooper, Lawrence C. Kenyon, Edward Andrews, Larry Harshyne, Kirsten M. Hooper, David W. Andrews
Publikováno v:
Cancer immunology, immunotherapy : CII. 64(3)
Glioblastomas are primary intracranial tumors for which there is no cure. Patients receiving standard of care, chemotherapy and irradiation, survive approximately 15 months prompting studies of alternative therapies including vaccination. In a pilot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce995a4cb0006ad93983e3bb2b7e4f97
https://pubmed.ncbi.nlm.nih.gov/25391690
https://pubmed.ncbi.nlm.nih.gov/25391690
Publikováno v:
The Journal of Immunology. 196:189.9-189.9
Interleukin-27 (p28/EBI3) is an immunomodulatory cytokine expressed by activated antigen presenting cells. Although first discovered to be involved in Th1 cell differentiation, further studies demonstrated the immunosuppressive functions of IL-27 inc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::02fd9228e4e9b1b0db43025658773eb6
https://doi.org/10.4049/jimmunol.196.supp.189.9
https://doi.org/10.4049/jimmunol.196.supp.189.9