Killer Cell Immunoglobulin-like Receptor Variants Are Associated with Protection from Symptoms Associated with More Severe Course in Parkinson Disease

Autor: Peter Parham, Mohammad R. K. Mofrad, Paul Norman, Neda Nemat-Gorgani, Wesley M. Marin, Tasneem Yusufali, Ravi Dandekar, Jill A. Hollenbach, Stacy J. Caillier, Marcelo Fernandez-Vina, Danillo G. Augusto, Kirsten M. Anderson, Hengameh Shams, Lisa E. Creary, Chao Zhao, Jorge R. Oksenberg, Gonzalo Montero-Martín

Publikováno v: Journal of immunology (Baltimore, Md. : 1950), vol 205, iss 5
J Immunol

Immune dysfunction plays a role in the development of Parkinson disease (PD). NK cells regulate immune functions and are modulated by killer cell immunoglobulin-like receptors (KIR). KIR are expressed on the surface of NK cells and interact with HLA

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41511bff8e1b12eb49de59e23be99fc3
https://doi.org/10.4049/jimmunol.2000144

HLA-A Locus is Associated With Sepsis and Septic Shock After Traumatic Injury

Autor: Dara L Horn, Jill A. Hollenbach, Ming Li, Chunlin Wang, Sujatha Krishnakumar, Grant E. O'Keefe, Kirsten M. Anderson, Michael N. Mindrinos

Publikováno v: Ann Surg

Objective Determine whether variation in the HLA region is associated with the development of post-traumatic sepsis and septic shock. Background Sepsis-related deaths remain a major source of mortality after traumatic injury. Genetic characteristics

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e194702d2fdead4ab44892a2d676429
https://europepmc.org/articles/PMC10060028/

A specific amino acid motif of HLA-DRB1 mediates risk and interacts with smoking history in Parkinson’s disease

Autor: Marcelo Fernandez-Vina, Stephen L. Hauser, Maneesh K. Misra, Wesley M. Marin, Jorge R. Oksenberg, Jill A. Hollenbach, Neda Nemat-Gorgani, Adam Renschen, Adam Santaniello, Lisa E. Creary, Kirsten M. Anderson, Gonzalo Montero-Martín, Vincent Damotte, Caroline M. Tanner, Kazutoyo Osoegawa, Paul Norman, Peter Parham, Ravi Dandekar, Stacy J. Caillier

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America, vol 116, iss 15

Significance Parkinson’s disease (PD) is a chronic, progressive neurodegenerative disease with both familial and sporadic forms and a clear genetic component. In addition, underlying immunoregulatory dysfunction and inflammatory processes have been

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c292928d2d116e0c807d5e35c253e992
http://europepmc.org/articles/PMC6462083

Carbon Fiber-Based Twisted and Coiled Artificial Muscles (TCAMs) for Powered Ankle-Foot Orthoses

Autor: Jason M. Wilken, Parth Kotak, Caterina Lamuta, Kirsten M. Anderson

Publikováno v: Journal of biomechanical engineering. 144(1)

Ankle foot orthoses (AFOs) control the position and motion of the ankle, compensate for weakness, and correct deformities. AFOs can be classified as passive or powered. Powered AFOs overcome the limitations of passive AFOs by adapting their performan

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c7fab7e1cce0338f427daab8d76f091
https://pubmed.ncbi.nlm.nih.gov/34318320

Findings from Formative Research to Develop a Strength-Based HIV Prevention and Sexual Health Promotion mHealth Intervention for Transgender Women

Autor: Christina J. Sun, Liat Tzvia Mayer, Charles H. Klein, Kirsten M. Anderson, Tamara Kuhn

Publikováno v: Transgender Health
Transgender Health, Vol, Iss, Pp-(2019)

Purpose: Transgender women experience significant health disparities, including increased risk of HIV infection. In this study, we examined the sexual health needs of transgender women in the context of their overall health and well-being and to iden

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3bcb6154ee7c34c9427bf26fa7f65c7f
https://doi.org/10.1089/trgh.2019.0032