Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Kirsten Himmler"'
Autor:
Frank T. Stümpel, Juliane Stein, Kirsten Himmler, Beatrix Scholz, Matthias D. Seidl, Boris V. Skryabin, Frank U. Müller
Publikováno v:
Frontiers in Pharmacology, Vol 9 (2018)
Background: Atrial fibrillation (AF) is a significant cause of morbidity and mortality with foreseeably increasing prevalence. While large animal models of the disease are well established but resource intensive, transgenic AF mouse models are not ye
Externí odkaz:
https://doaj.org/article/bb751c088c94441da8023a0cc5595818
Autor:
Uwe Lendeckel, Kirsten Himmler, Andreas Gardemann, Carmen Wolke, Jan S. Schulte, Edda Fehrmann, Beatrix Scholz, Matthias D. Seidl, F.U. Müller, Eva Wardelmann, Andreas Goette, Alicja Bukowska, M. Felgendreher
Publikováno v:
Thrombosis Research. 163:172-179
The molecular pathomechanisms underlying atrial thrombogenesis are multifactorial and still require detailed investigations. Transgenic mice with cardiomyocyte-directed expression of the transcriptional repressor CREM-IbΔC-X (CREM-TG) represent an e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4419aad97b819a9252fa2ca86804dfbb
https://doi.org/10.1016/j.thromres.2017.07.033
https://doi.org/10.1016/j.thromres.2017.07.033
Autor:
Hans-Heinrich Kreipe, Andrea Schienke, Axel Schambach, Gudrun Göhring, Maike Hagedorn, Brigitte Schlegelberger, Andreas Krueger, Azam Salari, Juliane Ebersold, Kirsten Himmler, Beate Vajen, Kathrin Thomay
Publikováno v:
Cancer Genetics. 209:258-266
Myelodysplastic syndromes (MDS) are difficult to culture long-term showing the need of a model to study the fate of cells with MDS-abnormalities associated with chromosomal instability (CIN). This approach to establish a xenograft model transplanting
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99cc2096447b91e9f69cebf6c3e90811
https://doi.org/10.1016/j.cancergen.2016.04.004
https://doi.org/10.1016/j.cancergen.2016.04.004
Autor:
Matthias D. Seidl, Elke Hammer, Juliane Stein, Florentina Pluteanu, Kirsten Himmler, Uwe Völker, Eva Wardelmann, Beatrix Scholz, Frank U. Müller, Sabine Hamer, Jan S. Schulte
Publikováno v:
Circulation. Arrhythmia and Electrophysiology
Supplemental Digital Content is available in the text.
Background: A structural, electrical and metabolic atrial remodeling is central in the development of atrial fibrillation (AF) contributing to its initiation and perpetuation. In the heart,
Background: A structural, electrical and metabolic atrial remodeling is central in the development of atrial fibrillation (AF) contributing to its initiation and perpetuation. In the heart,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::931a50ebc20f3b073eb7a9e6a4757d2b
http://europepmc.org/articles/PMC6426346
http://europepmc.org/articles/PMC6426346
Autor:
Wilhelm Schmitz, Matthias D. Seidl, Uwe Kirchhefer, Volker Gerke, Marcia A. Kaetzel, Alexander Heinick, Frank Ulrich Müller, Frank Nunes, John R. Dedman, Christina Rolfes, Jan S. Schulte, Xenia Husser, Kirsten Himmler
Publikováno v:
FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 29(9)
Annexin A4 (AnxA4), a Ca(2+)- and phospholipid-binding protein, is up-regulated in the human failing heart. In this study, we examined the impact of AnxA4 on β-adrenoceptor (β-AR)/cAMP-dependent signal transduction. Expression of murine AnxA4 in hu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4a923271128107edc218fc1e94c7217
https://pubmed.ncbi.nlm.nih.gov/26023182
https://pubmed.ncbi.nlm.nih.gov/26023182