Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Kirsten Guse"'
Autor:
Lisa Thiele née Schrewe, Kirsten Guse, Silvia Tietz, Jana Remlinger, Seray Demir, Xiomara Pedreiturria, Robert Hoepner, Anke Salmen, Maximilian Pistor, Timothy Turner, Britta Engelhardt, Dirk M. Hermann, Fred Lühder, Stefan Wiese, Andrew Chan
Publikováno v:
Journal of Neuroinflammation, Vol 17, Iss 1, Pp 1-9 (2020)
Abstract Background The multi-drug resistance transporter ABCG2, a member of the ATP-binding cassette (ABC) transporter family, mediates the efflux of different immunotherapeutics used in multiple sclerosis (MS), e.g., teriflunomide (teri), cladribin
Externí odkaz:
https://doaj.org/article/7192c5f5a49342408e5e811a46b98eff
Autor:
Emily F. Willis, Ellen R. Gillespie, Kirsten Guse, Adrian W. Zuercher, Fabian Käsermann, Marc J. Ruitenberg, Jana Vukovic
Publikováno v:
Brain, Behavior, and Immunity. 109:37-50
Intravenous immunoglobulin (IVIG) is a promising immune-modulatory therapy for limiting harmful inflammation and associated secondary tissue loss in neurotrauma. Here, we show that IVIG therapy attenuates spatial learning and memory deficits followin
Autor:
Seray Demir, Andrew Chan, Kirsten Guse, Lisa Schrewe, Fred Lühder, Britta Engelhardt, Silvia Tietz, Dirk M. Hermann, Maximilian Pistor, Robert Hoepner, Jana Remlinger, Timothy Turner, Xiomara Pedreiturria, Anke Salmen, Stefan Wiese
Publikováno v:
Journal of Neuroinflammation, Vol 17, Iss 1, Pp 1-9 (2020)
Journal of Neuroinflammation
Thiele née Schrewe, Lisa; Guse, Kirsten; Tietz, Silvia; Remlinger, Jana; Demir, Seray; Pedreiturria, Xiomara; Hoepner, Robert; Salmen, Anke; Pistor, Maximilian; Turner, Timothy; Engelhardt, Britta; Hermann, Dirk M; Lühder, Fred; Wiese, Stefan; Chan, Andrew (2020). Functional relevance of the multi-drug transporter abcg2 on teriflunomide therapy in an animal model of multiple sclerosis. Journal of neuroinflammation, 17(1), p. 9. BioMed Central 10.1186/s12974-019-1677-z
Journal of Neuroinflammation
Thiele née Schrewe, Lisa; Guse, Kirsten; Tietz, Silvia; Remlinger, Jana; Demir, Seray; Pedreiturria, Xiomara; Hoepner, Robert; Salmen, Anke; Pistor, Maximilian; Turner, Timothy; Engelhardt, Britta; Hermann, Dirk M; Lühder, Fred; Wiese, Stefan; Chan, Andrew (2020). Functional relevance of the multi-drug transporter abcg2 on teriflunomide therapy in an animal model of multiple sclerosis. Journal of neuroinflammation, 17(1), p. 9. BioMed Central 10.1186/s12974-019-1677-z
BackgroundThe multi-drug resistance transporter ABCG2, a member of the ATP-binding cassette (ABC) transporter family, mediates the efflux of different immunotherapeutics used in multiple sclerosis (MS), e.g., teriflunomide (teri), cladribine, and mit
Autor:
Kirsten Guse, Nina Hagemann, Lisa Thiele, Jana Remlinger, Anke Salmen, Robert Hoepner, Irene Keller, Patricia Meyer, Denis Grandgirard, Stephen L. Leib, Erik Vassella, Giuseppe Locatelli, Dirk M. Hermann, Andrew Chan
Publikováno v:
Guse, Kirsten; Hagemann, Nina; Thiele, Lisa; Remlinger, Jana; Salmen, Anke; Hoepner, Robert; Keller, Irene; Meyer, Patricia; Grandgirard, Denis; Leib, Stephen; Vassella, Erik; Locatelli, Giuseppe; Hermann, Dirk M; Chan, Andrew Hao-Kuang (2022). CNS Antigen-Specific Neuroinflammation Attenuates Ischemic Stroke With Involvement of Polarized Myeloid Cells. Neurology: neuroimmunology & neuroinflammation, 9(4) Wolters Kluwer Health 10.1212/NXI.0000000000001168
Background and ObjectivesExperimental studies indicate shared molecular pathomechanisms in cerebral hypoxia-ischemia and autoimmune neuroinflammation. This has led to clinical studies investigating the effects of immunomodulatory therapies approved i
Autor:
Jana Remlinger, Adrian Madarasz, Kirsten Guse, Robert Hoepner, Maud Bagnoud, Ivo Meli, Moritz Feil, Mathias Abegg, Christopher Linington, Anthony Shock, Babak Boroojerdi, Peter Kiessling, Bryan Smith, Volker Enzmann, Andrew Chan, Anke Salmen
Publikováno v:
Remlinger, Jana; Madarasz, Adrian; Guse, Kirsten; Hoepner, Robert; Bagnoud, Maud; Meli, Ivo; Feil, Moritz; Abegg, Mathias; Linington, Christopher; Shock, Anthony; Boroojerdi, Babak; Kiessling, Peter; Smith, Bryan; Enzmann, Volker; Chan, Andrew; Salmen, Anke (2022). Antineonatal Fc Receptor Antibody Treatment Ameliorates MOG-IgG-Associated Experimental Autoimmune Encephalomyelitis. Neurology: neuroimmunology & neuroinflammation, 9(2) Wolters Kluwer Health 10.1212/NXI.0000000000001134
Neurology® Neuroimmunology & Neuroinflammation
article-version (Version of Record) 3
Neurology® Neuroimmunology & Neuroinflammation
article-version (Version of Record) 3
Background and ObjectivesMyelin oligodendrocyte glycoprotein antibody–associated disorder (MOGAD) is a rare, autoimmune demyelinating CNS disorder, distinct from multiple sclerosis and neuromyelitis optica spectrum disorder. Characterized by pathog
Autor:
Andrew Chan, Maud Bagnoud, Seray Demir, Paul F. Worley, Farhad Ahmadi, Melissa Gresle, Holger M. Reichardt, Kirsten Guse, Lisa Schrewe, Maximilian Pistor, Helen Synn, Myriam Briner, Ralf Gold, Imke Metz, Anke Salmen, Helmut Butzkueven, Louis Laverick, Robert Hoepner, Fred Lühder
Publikováno v:
Hoepner, Robert; Bagnoud, Maud; Pistor, Maximilian; Salmen, Anke; Briner, Myriam; Synn, Helen; Schrewe, Lisa; Guse, Kirsten; Ahmadi, Farhad; Demir, Seray; Laverick, Louis; Gresle, Melissa; Worley, Paul; Reichardt, Holger Michael; Butzkueven, Helmut; Gold, Ralf; Metz, Imke; Lühder, Fred; Chan, Andrew (2019). Vitamin D increases glucocorticoid efficacy via inhibition of mTORC1 in experimental models of multiple sclerosis. Acta neuropathologica, 138(3), pp. 443-456. Springer-Verlag 10.1007/s00401-019-02018-8
Acta Neuropathologica
Acta Neuropathologica
The limited efficacy of glucocorticoids (GCs) during therapy of acute relapses in multiple sclerosis (MS) leads to long-term disability. We investigated the potential of vitamin D (VD) to enhance GC efficacy and the mechanisms underlying this VD/GC i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a60fed6e5a2c39aac01cced7d660fbbd
Autor:
Björn, Ambrosius, Simon, Faissner, Kirsten, Guse, Marec, von Lehe, Thomas, Grunwald, Ralf, Gold, Bastian, Grewe, Andrew, Chan
Publikováno v:
Journal of Neuroinflammation
HIV-associated neurocognitive disorders (HAND) affect about 50% of infected patients despite combined antiretroviral therapy (cART). Ongoing compartmentalized inflammation mediated by microglia which are activated by HIV-infected monocytes has been p