Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Kirsten Göpelt"'
Autor:
Tobias Ocklenburg, Fabian Neumann, Alexandra Wolf, Julia Vogel, Kirsten Göpelt, Melanie Baumann, Jennifer Baumann, Philip Kranz, Eric Metzen, Ulf Brockmeier
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract The disulfide isomerase ERp57, originally found in the endoplasmic reticulum, is located in multiple cellular compartments, participates in diverse cell functions and interacts with a huge network of binding partners. It was recently suggest
Externí odkaz:
https://doaj.org/article/70c99fc6b9384a9d8053fe7ddefd8962
Autor:
Alina Küper, Jennifer Baumann, Kirsten Göpelt, Melanie Baumann, Christopher Sänger, Eric Metzen, Philip Kranz, Ulf Brockmeier
Publikováno v:
Cell Death and Disease, Vol 12, Iss 1, Pp 1-11 (2021)
Abstract Hypoxia-induced resistance of tumor cells to therapeutic treatment is an unresolved limitation due to poor vascular accessibility and protective cell adaptations provided by a network, including PERK, NRF2, and HIF signaling. All three pathw
Externí odkaz:
https://doaj.org/article/b791e66bbfba41b79cde36f1dc44fca4
Autor:
Akram Hamidi, Alexandra Wolf, Rositsa Dueva, Melanie Kaufmann, Kirsten Göpelt, George Iliakis, Eric Metzen
Publikováno v:
Cells, Vol 11, Iss 10, p 1671 (2022)
The transcription factor hypoxia-inducible factor (HIF) is the main oxygen sensor which regulates adaptation to cellular hypoxia. The aim of this study was to establish cultured murine hepatocyte derived cells (mHDC) as an in vitro model and to analy
Externí odkaz:
https://doaj.org/article/7c7ee49dc85645e1a4abed214fcb5df1
Autor:
Philip Kranz, Helena Riffkin, Eric Metzen, Alexandra Wolf, Ulf Brockmeier, Fabian Classen, Mosche Pompsch, Kirsten Göpelt, Jennifer Baumann, Melanie Baumann
Publikováno v:
Experimental Cell Research. 374:29-37
Autophagy is commonly described as a cell survival mechanism and has been implicated in chemo- and radioresistance of cancer cells. Whether ionizing radiation induced autophagy triggers tumor cell survival or cell death still remains unclear. In this
Autor:
Eric Metzen, Fabian Neumann, Jennifer Baumann, Melanie Baumann, Alexandra Wolf, Kirsten Göpelt, Julia Vogel, Philip Kranz, Tobias Ocklenburg, Ulf Brockmeier
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Scientific Reports
Scientific Reports
The disulfide isomerase ERp57, originally found in the endoplasmic reticulum, is located in multiple cellular compartments, participates in diverse cell functions and interacts with a huge network of binding partners. It was recently suggested as an
Autor:
Kirsten Göpelt, Melanie Baumann, Philip Kranz, Eric Metzen, Christopher Sänger, Ulf Brockmeier, Jennifer Baumann, Alina Küper
Publikováno v:
Cell Death and Disease, Vol 12, Iss 1, Pp 1-11 (2021)
Cell Death & Disease
Cell Death & Disease
Hypoxia-induced resistance of tumor cells to therapeutic treatment is an unresolved limitation due to poor vascular accessibility and protective cell adaptations provided by a network, including PERK, NRF2, and HIF signaling. All three pathways have
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad421f9a64f4cbec4bd93f30a6bae9a4
https://www.ncbi.nlm.nih.gov/pubmed/33441543
https://www.ncbi.nlm.nih.gov/pubmed/33441543
Autor:
Eric Metzen, Alexandra Wolf, Philip Kranz, Jennifer Baumann, Kirsten Göpelt, Christopher Sänger, Melanie Baumann, Ulf Brockmeier
Publikováno v:
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-11 (2020)
Scientific Reports, Vol 10, Iss 1, Pp 1-11 (2020)
Upon ER stress cells activate the unfolded protein response through PERK, IRE1 and ATF6. Remarkable effort has been made to delineate the downstream signaling of these three ER stress sensors after activation, but upstream regulation at the ER lumina