Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Kirsten Dundas"'
Autor:
Rameswara R. Segireddy, Hugo Belda, Annie S. P. Yang, Kirsten Dundas, Julia Knoeckel, Francis Galaway, Laura Wood, Doris Quinkert, Ellen Knuepfer, Moritz Treeck, Gavin J. Wright, Alexander D. Douglas
Publikováno v:
Malaria Journal, Vol 23, Iss 1, Pp 1-19 (2024)
Abstract Background Sporozoite invasion of hepatocytes is an essential step in the Plasmodium life-cycle and has similarities, at the cellular level, to merozoite invasion of erythrocytes. In the case of the Plasmodium blood-stage, efforts to identif
Externí odkaz:
https://doaj.org/article/cd30976dbd8d4667bc3b6da3dc678722
Autor:
Rameswara R Segireddy, Hugo Belda, Annie S. P. Yang, Kirsten Dundas, Julia Knoeckel, Francis Galaway, Laura Wood, Doris Quinkert, Ellen Knuepfer, Moritz Treeck, Gavin J Wright, Alexander D Douglas
Sporozoite invasion of hepatocytes is an essential step in the Plasmodium life-cycle and has similarities, at the cellular level, to merozoite invasion of erythrocytes. In the case of the Plasmodium blood-stage, efforts to identify host-pathogen prot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a43697a9acba1104a2741457578626a7
https://doi.org/10.21203/rs.3.rs-2104273/v1
https://doi.org/10.21203/rs.3.rs-2104273/v1
Publikováno v:
Trends in Parasitology. 35:129-139
Malaria is an infectious disease, caused by Plasmodium parasites, that remains a major global health problem. Infection begins when salivary gland sporozoites are transmitted through the bite of an infected mosquito. Once within the host, sporozoites
Autor:
Kirsten Dundas, Julia Knöckel, Julian C. Rayner, Oliver Billker, Annie S. P. Yang, Francis Galaway, Robert W. Sauerwein, Tom Metcalf, Geert-Jan van Gemert, Gavin J. Wright
Publikováno v:
Molecular & Cellular Proteomics, 20
Molecular & Cellular Proteomics : MCP
Molecular & Cellular Proteomics : MCP
Sporozoites are a motile form of malaria-causing Plasmodium falciparum parasites that migrate from the site of transmission in the dermis through the bloodstream to invade hepatocytes. Sporozoites interact with many cells within the host, but the mol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8eabf6b982f14e4c82ab21144bb703c5
http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-181830
http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-181830
Autor:
Laura Wood, Francis Galaway, Alexander D. Douglas, Gavin J. Wright, J Knoeckel, R R Segireddy, Kirsten Dundas
Publikováno v:
TBD
bioRxiv
bioRxiv
Sporozoite invasion of hepatocytes is a necessary step prior to development of malaria, with similarities, at the cellular level, to merozoite invasion of erythrocytes. In the case of the malaria blood-stage, efforts to identify host-pathogen protein
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16468da5139fee96908dd6e8f435dac6
Autor:
Ana Rita Gomes, Kirsten Dundas, Lia Chappell, Jyoti S. Choudhary, Katarzyna Modrzynska, Lu Yu, Catherine Suarez, David Goulding, Oliver Billker, Claudia Pfander, Julian C. Rayner
Publikováno v:
Cell Host & Microbe
Summary A family of apicomplexa-specific proteins containing AP2 DNA-binding domains (ApiAP2s) was identified in malaria parasites. This family includes sequence-specific transcription factors that are key regulators of development. However, function
Autor:
Alexander M. Lewis, Sridhar R. Vasudevan, Amanda J. Sadler, Katherine L. Tucker, Carmen H. Coxon, Lewis Taylor, Grant C. Churchill, Andrew C. Thomas, R. Duncan Campbell, Kirsten Dundas, Jonathan M. Gibbins
Publikováno v:
The Biochemical journal. 441(1)
Platelets play a vital role in maintaining haemostasis. Human platelet activation depends on Ca2+ release, leading to cell activation, granule secretion and aggregation. NAADP (nicotinic acid–adenine dinucleotide phosphate) is a Ca2+-releasing seco
Autor:
Gavin J. Wright, Kirsten Dundas, Cécile Crosnier, Gareth Girling, Yi Sun, Photini Sinnis, Oliver Billker, Tom Metcalf, Christine S. Hopp, Melanie J. Shears
Publikováno v:
Proceedings of the National Academy of Sciences
Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America
Significance Malaria is caused by a parasite that is deposited in the skin through the bite of an infected mosquito. From the skin, parasites navigate through host tissues where they must locate and invade liver cells. We know that a parasite surface