An SMC-like protein binds and regulates Caenorhabditis elegans condensins.

Autor: Lucy Fang-I Chao, Meha Singh, James Thompson, John R Yates, Kirsten A Hagstrom

Publikováno v: PLoS Genetics, Vol 13, Iss 3, p e1006614 (2017)

Structural Maintenance of Chromosomes (SMC) family proteins participate in multisubunit complexes that govern chromosome structure and dynamics. SMC-containing condensin complexes create chromosome topologies essential for mitosis/meiosis, gene expre

Externí odkaz: https://doaj.org/article/180edfa008644aa99003a27d20b0f6c3

The enhancement of histone H4 and H2A serine 1 phosphorylation during mitosis and S-phase is evolutionarily conserved

Autor: Sean D. Taverna, Barbara J Meyer, Donald F. Hunt, C. David Allis, Beatrix Ueberheide, Cynthia M. Barber, Kirsten A. Hagstrom, Yanming Wang, Fiona B. Turner, Peter Cheung, Sahana Mollah

Publikováno v: Chromosoma. 112:360-371

Histone phosphorylation has long been associated with condensed mitotic chromatin; however, the functional roles of these modifications are not yet understood. Histones H1 and H3 are highly phosphorylated from late G2 through telophase in many organi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba90c1435ba73895c0944a8878cb67b0
https://doi.org/10.1007/s00412-004-0281-9

An SMC-like protein binds and regulates Caenorhabditis elegans condensins

Autor: Meha Singh, Kirsten A. Hagstrom, Lucy Fang-I Chao, James Thompson, John R. Yates

Publikováno v: PLoS Genetics
PLoS Genetics, Vol 13, Iss 3, p e1006614 (2017)

Structural Maintenance of Chromosomes (SMC) family proteins participate in multisubunit complexes that govern chromosome structure and dynamics. SMC-containing condensin complexes create chromosome topologies essential for mitosis/meiosis, gene expre

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7735a2924ee85cf6e07b2cc9ce833ec
https://doi.org/10.1371/journal.pgen.1006614

Opposing activities of DRM and MES-4 tune gene expression and X-chromosome repression in Caenorhabditis elegans germ cells

Autor: Susan Strome, Andreas Rechtsteiner, Tomoko M. Tabuchi, Kirsten A. Hagstrom

Publikováno v: G3 (Bethesda, Md.), vol 4, iss 1
Tabuchi, TM; Rechtsteiner, A; Strome, S; & Hagstrom, KA. (2014). Opposing activities of DRM and MES-4 tune gene expression and x-chromosome repression in aenorhabditis elegans germ cells. G3: Genes, Genomes, Genetics, 4(1), 143-153. doi: 10.1534/g3.113.007849. UC Santa Cruz: Retrieved from: http://www.escholarship.org/uc/item/8d67w70q
G3: Genes|Genomes|Genetics

During animal development, gene transcription is tuned to tissue-appropriate levels. Here we uncover antagonistic regulation of transcript levels in the germline of Caenorhabditis elegans hermaphrodites. The histone methyltransferase MES-4 (Maternal

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da7955257395750a6170e0d26ee5643d
https://escholarship.org/uc/item/8d67w70q

Chromosome-biased binding and gene regulation by the Caenorhabditis elegans DRM complex

Autor: Kirsten A. Hagstrom, H. Robert Horvitz, Albertha J.M. Walhout, Melissa M. Harrison, Tomoko M. Tabuchi, M. Inmaculada Barrasa, Lihua Julie Zhu, Bart Deplancke, Naoki Osato

Publikováno v: PLoS Genetics
PLoS
PLoS Genetics, Vol 7, Iss 5, p e1002074 (2011)

DRM is a conserved transcription factor complex that includes E2F/DP and pRB family proteins and plays important roles in development and cancer. Here we describe new aspects of DRM binding and function revealed through genome-wide analyses of the Ca

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40064fc8b9767e944ee7ffe90ad1d81c
https://pubmed.ncbi.nlm.nih.gov/21589891