Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Kirsten A Cottrill"'
Autor:
Kirsten A. Cottrill, Milad G. Rad, Michael J. Ripple, Susan T. Stephenson, Ahmad F. Mohammad, Mallory Tidwell, Rishikesan Kamaleswaran, Anne M. Fitzpatrick, Jocelyn R. Grunwell
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract Children with life-threatening asthma exacerbations who are admitted to a pediatric intensive care unit (PICU) are a heterogeneous group with poorly studied inflammatory features. We hypothesized that distinct clusters of children with asthm
Externí odkaz:
https://doaj.org/article/1c5273c896094355aa40956e79493633
Autor:
Kirsten A. Cottrill, PhD, Joshua D. Chandler, PhD, Seibi Kobara, PT, MPH, Susan T. Stephenson, PhD, Ahmad F. Mohammad, BS, Mallory Tidwell, BSN, RN, Carrie Mason, BS, RRT, Morgan Van Dresser, RN, MSN, James Patrignani, BS, Rishikesan Kamaleswaran, PhD, Anne M. Fitzpatrick, PhD, Jocelyn R. Grunwell, MD, PhD
Publikováno v:
Journal of Allergy and Clinical Immunology: Global, Vol 2, Iss 3, Pp 100115- (2023)
Background: Asthma exacerbations are highly prevalent in children, but only a few studies have examined the biologic mechanisms underlying exacerbations in this population. Objective: High-resolution metabolomics analyses were performed to understand
Externí odkaz:
https://doaj.org/article/5746c2beef024cdc9598c77f80111afd
Autor:
Kirsten A. Cottrill, Vincent D. Giacalone, Camilla Margaroli, Robert J. Bridges, Michael Koval, Rabindra Tirouvanziam, Nael A. McCarty
Publikováno v:
Physiological Reports, Vol 9, Iss 17, Pp n/a-n/a (2021)
Abstract Loss of function of the cystic fibrosis transmembrane conductance regulator (CFTR) causes cystic fibrosis (CF). In the lungs, this manifests as immune cell infiltration and bacterial infections, leading to tissue destruction. Previous work h
Externí odkaz:
https://doaj.org/article/643f626715024b628d46003c13d0b820
Autor:
Kirsten A. Cottrill, Raven J. Peterson, Colby F. Lewallen, Michael Koval, Robert J. Bridges, Nael A. McCarty
Publikováno v:
Physiological Reports, Vol 9, Iss 15, Pp n/a-n/a (2021)
Abstract The cystic fibrosis transmembrane conductance regulator (CFTR) is an anion channel whose dysfunction causes cystic fibrosis (CF). The loss of CFTR function in pulmonary epithelial cells causes surface dehydration, mucus build‐up, inflammat
Externí odkaz:
https://doaj.org/article/ab84396bd5ba466c8fa59996606ebd95
Autor:
Delaney K Geitgey, Miyoung Lee, Kirsten A Cottrill, Maya Jaffe, William Pilcher, Swati Bhasin, Jessica Randall, Anthony J Ross, Michelle Salemi, Marisol Castillo-Castrejon, Matthew B Kilgore, Ayjha C Brown, Jeremy M Boss, Rich Johnston, Anne M Fitzpatrick, Melissa L Kemp, Robert English, Eric Weaver, Pritha Bagchi, Ryan Walsh, Christopher D Scharer, Manoj Bhasin, Joshua D Chandler, Karmella A Haynes, Elizabeth A Wellberg, Curtis J Henry
Publikováno v:
JNCI Monographs. 2023:12-29
The obesity pandemic currently affects more than 70 million Americans and more than 650 million individuals worldwide. In addition to increasing susceptibility to pathogenic infections (eg, SARS-CoV-2), obesity promotes the development of many cancer
Autor:
Guiying Cui, Kirsten A. Cottrill, Kerry M. Strickland, Sarah A. Mashburn, Michael Koval, Nael A. McCarty
Publikováno v:
Frontiers in Physiology, Vol 12 (2021)
Altered cholesterol homeostasis in cystic fibrosis patients has been reported, although controversy remains. As a major membrane lipid component, cholesterol modulates the function of multiple ion channels by complicated mechanisms. However, whether
Externí odkaz:
https://doaj.org/article/2bf8cf834f1c40d3aa91a0b1d0b07942
Publikováno v:
Journal of Microbiology & Biology Education, Vol 19, Iss 2 (2018)
Undergraduate microbiology courses offer a perfect opportunity to introduce students to historical food preservation processes that are still in use today. Specifically, food fermentation exercises encourage students to consider other cultures and th
Externí odkaz:
https://doaj.org/article/a23f9d943bd24660aaf5a54497b6cc93
Autor:
Anne M. Fitzpatrick, Jocelyn R. Grunwell, Kirsten A. Cottrill, Abby D. Mutic, David T. Mauger
Publikováno v:
The Journal of Allergy and Clinical Immunology: In Practice. 11:1485-1493.e8
Autor:
Kirsten A. Cottrill, Susan T. Stephenson, Ahmad F. Mohammad, Susan O. Kim, Nael A. McCarty, Rishikesan Kamaleswaran, Anne M. Fitzpatrick, Joshua D. Chandler
Publikováno v:
The Journal of allergy and clinical immunology. 151(1)
The asthma of some children remains poorly controlled, with recurrent exacerbations despite treatment with inhaled corticosteroids. Aside from prior exacerbations, there are currently no reliable predictors of exacerbation-prone asthma in these child
Publikováno v:
Communications Biology, Vol 3, Iss 1, Pp 1-10 (2020)
Communications Biology
Communications Biology
Cystic Fibrosis (CF) is the most common life-shortening genetic disease among Caucasians, resulting from mutations in the gene encoding the Cystic Fibrosis Transmembrane conductance Regulator (CFTR). While work to understand this protein has resulted