Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Kirsten, Fraedrich"'
Autor:
Dennis Lapuente, Jana Fuchs, Jonas Willar, Ana Vieira Antão, Valentina Eberlein, Nadja Uhlig, Leila Issmail, Anna Schmidt, Friederike Oltmanns, Antonia Sophia Peter, Sandra Mueller-Schmucker, Pascal Irrgang, Kirsten Fraedrich, Andrea Cara, Markus Hoffmann, Stefan Pöhlmann, Armin Ensser, Cordula Pertl, Torsten Willert, Christian Thirion, Thomas Grunwald, Klaus Überla, Matthias Tenbusch
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
While current COVID-19 vaccines provide certain protection, more effective vaccination strategies are still desirable. Here the authors show, using mouse vaccination models, that priming with a systemic mRNA and boosting with an intranasal adenoviral
Externí odkaz:
https://doaj.org/article/2d658f5bfe1141c4acf2fa4bf72300b6
Autor:
Stephan Klessing, Antonia Sophia Peter, Kirsten Fraedrich, Jannik T. Wagner, Mirko Kummer, Janina Deutschmann, Philipp Steininger, Hans-Dieter Steibl, Klaus Überla
Publikováno v:
Viruses, Vol 15, Iss 2, p 397 (2023)
Live-attenuated SARS-CoV-2 vaccines present themselves as a promising approach for the induction of broad mucosal immunity. However, for initial safety assessment in clinical trials, virus production requires conditions meeting Good Manufacturing Pra
Externí odkaz:
https://doaj.org/article/cef303dff024458ca4eb53d2e12b97eb
Autor:
Friedrich Hahn, Sigrun Häge, Alexandra Herrmann, Christina Wangen, Jintawee Kicuntod, Doris Jungnickl, Julia Tillmanns, Regina Müller, Kirsten Fraedrich, Klaus Überla, Hella Kohlhof, Armin Ensser, Manfred Marschall
Publikováno v:
Pathogens, Vol 10, Iss 9, p 1076 (2021)
Currently, human infections with the severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2) are accelerating the ongoing spread of the pandemic. Several innovative types of vaccines have already been developed, whereas effective options of
Externí odkaz:
https://doaj.org/article/b059dfdcbad14989be1d8b94db18bdef
Autor:
Friedrich Hahn, Adrian Schmalen, Christian Setz, Melanie Friedrich, Stefan Schlößer, Julia Kölle, Robert Spranger, Pia Rauch, Kirsten Fraedrich, Tatjana Reif, Julia Karius-Fischer, Ashok Balasubramanyam, Petra Henklein, Torgils Fossen, Ulrich Schubert
Publikováno v:
PLoS ONE, Vol 12, Iss 4, p e0174254 (2017)
There is a significantly higher risk for type II diabetes in HIV-1 carriers, albeit the molecular mechanism for this HIV-related pathology remains enigmatic. The 52 amino acid HIV-1 p6 Gag protein is synthesized as the C-terminal part of the Gag poly
Externí odkaz:
https://doaj.org/article/ff4f74b40c1748b0ba8e1d0e7fc126d2
Autor:
Markus Hoffmann, Sandra Ciesek, Dirk Mielenz, Leila Issmail, Sebastian R. Schulz, Eileen Socher, Eva Grüner, Katharina Habenicht, Roman Wölfel, Paul F. McKay, Hans-Martin Jäck, Tobit Steinmetz, Robin J. Shattock, Ralf Wagner, Valentina Eberlein, Edith Roth, Heinrich Sticht, Jutta Eichler, Stefan Pöhlmann, Matthias Tenbusch, Frank Neipel, Wolfgang Schuh, Elie Richel, Kirsten Fraedrich, Thomas Winkler, Thomas Grunwald, Sandra Mueller-Schmucker, Antonia Sophia Peter, Simon Dolles, Klaus Überla, Nadja Uhlig, Armin Ensser, David Peterhoff, Dominik Damm, Manuela Hauke
Publikováno v:
European Journal of Immunology
TRIANNI mice carry an entire set of human immunoglobulin V region gene segments and are a powerful tool to rapidly isolate human monoclonal antibodies. After immunizing these mice with DNA encoding the spike protein of SARS‐CoV‐2 and boosting wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::afb13b928f02eaac23f497c4789f9a82
https://publica.fraunhofer.de/handle/publica/270534
https://publica.fraunhofer.de/handle/publica/270534
Autor:
Markus Hoffmann, Leila Issmail, Jana Fuchs, Thomas Grunwald, Andrea Cara, Anna Schmidt, Stefan Poehlmann, Torsten Willert, Matthias Tenbusch, Christian Thirion, Pascal Irrgang, Klaus Ueberla, Ana Vieira Antão, Valentina Everlein, Nadja Uhlig, Dennis Lapuente, Jonas Willar, Antonia Sophia Peter, Sandra Mueller-Schmucker, Armin Ensser, Friederike Oltmanns, Kirsten Fraedrich, Cordula Pertl
Several effective SARS-CoV-2 vaccines are currently in use, but in the light of waning immunity and the emergence of novel variants, effective boost modalities are needed in order to maintain or even increase immunity. Here we report that intranasal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8f02bd2865da324745bc4b02c72bc7fd
https://doi.org/10.1101/2021.08.03.454858
https://doi.org/10.1101/2021.08.03.454858
Autor:
Christian Setz, Melanie Friedrich, Pia Rauch, Kirsten Fraedrich, Alina Matthaei, Maximilian Traxdorf, Ulrich Schubert
Publikováno v:
Viruses, Vol 9, Iss 8, p 222 (2017)
In recent years it has been well established that two major constituent parts of the ubiquitin proteasome system (UPS)—the proteasome holoenzymes and a number of ubiquitin ligases—play a crucial role, not only in virus replication but also in the
Externí odkaz:
https://doaj.org/article/70df03217bc849728e8caf64404a3fa6
Autor:
Roman Wölfel, Paul F. McKay, Jutta Eichler, Stefan Pöhlmann, Manuela Hauke, Dirk Mielenz, Edith Roth, Eva Grüner, Matthias Tenbusch, Thomas Grunwald, Thomas Winkler, Tobit Steinmetz, Sebastian R. Schulz, Ralf Wagner, Heinrich Sticht, Markus Hoffmann, Hans-Martin Jäck, Sandra Ciesek, Dominik Damm, Valentina Eberlein, Eileen Socher, Leila Issmail, Katharina Habenicht, Armin Ensser, David Peterhoff, Elie Richel, Wolfgang Schuh, Klaus Überla, Nadja Uhlig, Antonia Sophia Peter, Simon Dolles, Frank Neipel, Sandra Mueller-Schmucker, Robin J. Shattock, Kirsten Fraedrich
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9eaa1c8052cb4bac143567d93e951dde
https://doi.org/10.1002/eji.202149374/v2/response1
https://doi.org/10.1002/eji.202149374/v2/response1
Autor:
Katharina Habenicht, Klaus Überla, Thomas Winkler, Frank Neipel, Sebastian R. Schulz, Antonia Sophia Peter, Simon Dolles, Wolfgang Schuh, Sandra Ciesek, Paul F. McKay, Thomas Grunwald, Roman Wölfel, Dominik Damm, Sandra Mueller-Schmucker, Manuela Hauke, Tobit Steinmetz, Ralf Wagner, Nadja Uhlig, Eva Grüner, Valentina Eberlein, Dirk Mielenz, Robin J. Shattock, Edith Roth, Matthias Tenbusch, Hans-Martin Jäck, Elie Richel, Markus Hoffmann, Jutta Eichler, Leila Issmail, Stefan Pöhlmann, Armin Ensser, David Peterhoff, Kirsten Fraedrich
TRIANNI mice carry an entire set of human immunoglobulin V region gene segments and are a powerful tool to rapidly generate human monoclonal antibodies. After immunizing these mice against the spike protein of SARS-CoV-2, we identified 29 hybridoma a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b2ba90ae976d4b6d13f0e8f3fb6a98bc
https://doi.org/10.1101/2021.04.16.440101
https://doi.org/10.1101/2021.04.16.440101
Autor:
Dennis, Lapuente, Jana, Fuchs, Jonas, Willar, Ana, Vieira Antão, Valentina, Eberlein, Nadja, Uhlig, Leila, Issmail, Anna, Schmidt, Friederike, Oltmanns, Antonia Sophia, Peter, Sandra, Mueller-Schmucker, Pascal, Irrgang, Kirsten, Fraedrich, Andrea, Cara, Markus, Hoffmann, Stefan, Pöhlmann, Armin, Ensser, Cordula, Pertl, Torsten, Willert, Christian, Thirion, Thomas, Grunwald, Klaus, Überla, Matthias, Tenbusch
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Nature Communications
Nature Communications
Several effective SARS-CoV-2 vaccines are currently in use, but effective boosters are needed to maintain or increase immunity due to waning responses and the emergence of novel variants. Here we report that intranasal vaccinations with adenovirus 5
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::0313d7c607e6f26032626105c6a5fa68
https://publica.fraunhofer.de/handle/publica/415910
https://publica.fraunhofer.de/handle/publica/415910