Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Kirsteen M, Tullett"'
Autor:
Rajan Venkatraman, Katherine R. Balka, Wilson Wong, Jananipriya Sivamani, Zoe Magill, Kirsteen M. Tullett, Rachael M. Lane, Tahnee L. Saunders, Maximilien Tailler, Peter J. Crack, Linda M. Wakim, Mireille H. Lahoud, Kate E. Lawlor, Benjamin T. Kile, Meredith O’Keeffe, Dominic De Nardo
Publikováno v:
iScience, Vol 27, Iss 9, Pp 110693- (2024)
Summary: The cGAS-STING pathway responds to cytosolic DNA to elicit host immunity to infection. The activation of stimulator of interferon genes (STING) can trigger a number of critical cellular responses including inflammation, noncanonical autophag
Externí odkaz:
https://doaj.org/article/4f6ffb7d172c46ffbb14376dc21aae1e
Autor:
Runqiu Song, Mariam Bafit, Kirsteen M. Tullett, Peck Szee Tan, Mireille H. Lahoud, Meredith O’Keeffe, Anthony W. Purcell, Asolina Braun
Publikováno v:
Methods and Protocols, Vol 7, Iss 2, p 20 (2024)
The generation of bone-marrow-derived dendritic cells is a widely used approach in immunological research to study antigen processing and presentation, as well as T-cell activation responses. However, the initial step of isolating the bone marrow can
Externí odkaz:
https://doaj.org/article/542cc4b101824deaaea3f74857518e9f
Autor:
Kirsteen M Tullett, Peck Szee Tan, Hae-Young Park, Ralf B Schittenhelm, Nicole Michael, Rong Li, Antonia N Policheni, Emily Gruber, Cheng Huang, Alex J Fulcher, Jillian C Danne, Peter E Czabotar, Linda M Wakim, Justine D Mintern, Georg Ramm, Kristen J Radford, Irina Caminschi, Meredith O'Keeffe, Jose A Villadangos, Mark D Wright, Marnie E Blewitt, William R Heath, Ken Shortman, Anthony W Purcell, Nicos A Nicola, Jian-Guo Zhang, Mireille H Lahoud
Publikováno v:
eLife, Vol 9 (2020)
The dendritic cell receptor Clec9A facilitates processing of dead cell-derived antigens for cross-presentation and the induction of effective CD8+ T cell immune responses. Here, we show that this process is regulated by E3 ubiquitin ligase RNF41 and
Externí odkaz:
https://doaj.org/article/ce7301ac4e2c47ffba46b495f1882e5b
Autor:
Kelly-Anne Masterman, Oscar L Haigh, Kirsteen M Tullett, Ingrid M Leal-Rojas, Carina Walpole, Frances E Pearson, Jonathon Cebon, Christopher Schmidt, Liam O'Brien, Nikita Rosendahl, Ghazal Daraj, Irina Caminschi, Eric H Gschweng, Roger P Hollis, Donald B Kohn, Mireille H Lahoud, Kristen J Radford
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss 2 (2020)
Background Dendritic cells (DCs) are crucial for the efficacy of cancer vaccines, but current vaccines do not harness the key cDC1 subtype required for effective CD8+ T-cell-mediated tumor immune responses. Vaccine immunogenicity could be enhanced by
Externí odkaz:
https://doaj.org/article/11cf9f6bcce340f58753253d7529688c
Autor:
Frances E Pearson, Kirsteen M Tullett, Ingrid M Leal‐Rojas, Oscar L Haigh, Kelly‐Anne Masterman, Carina Walpole, John S Bridgeman, James E McLaren, Kristin Ladell, Kelly Miners, Sian Llewellyn‐Lacey, David A Price, Antje Tunger, Marc Schmitz, John J Miles, Mireille H Lahoud, Kristen J Radford
Publikováno v:
Clinical & Translational Immunology, Vol 9, Iss 6, Pp n/a-n/a (2020)
Abstract Objectives Vaccines that prime Wilms' tumor 1 (WT1)‐specific CD8+ T cells are attractive cancer immunotherapies. However, immunogenicity and clinical response rates may be enhanced by delivering WT1 to CD141+ dendritic cells (DCs). The C
Externí odkaz:
https://doaj.org/article/d7716a6649ca41f9a6290ec9da9eae79
Autor:
Hannah A D King, Christopher A Gonelli, Kirsteen M Tullett, Mireille H Lahoud, Damian F J Purcell, Heidi E Drummer, Pantelis Poumbourios, Rob J Center
Publikováno v:
PLoS ONE, Vol 14, Iss 8, p e0220986 (2019)
A promising strategy for the enhancement of vaccine-mediated immune responses is by directly targeting protein antigens to immune cells. Targeting of antigens to the dendritic cell (DC) molecule Clec9A has been shown to enhance antibody affinity and
Externí odkaz:
https://doaj.org/article/d564ce87a08a43f9a3a3f5e3be9de528
Autor:
Benjamin S. Gully, Gayle M. Davey, Mireille H. Lahoud, Kirsteen M. Tullett, William R. Heath, Chin-Nien Lee, Meredith O'Keeffe, Daniel Fernandez-Ruiz, Jessica Li, Fatma Panetta, Kristen J. Radford, Jamie Rossjohn, Ingrid M. Leal Rojas, Richard Berry, Jian-Guo Zhang, Irina Caminschi
Publikováno v:
The Journal of Immunology. 207:1836-1847
DEC-205 is a cell-surface receptor that transports bound ligands into the endocytic pathway for degradation or release within lysosomal endosomes. This receptor has been reported to bind a number of ligands, including keratin, and some classes of CpG
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ee6603965fd99e40e17133684efd8a3a
https://doi.org/10.4049/jimmunol.2001153
https://doi.org/10.4049/jimmunol.2001153
Autor:
Kirsteen M. Tullett, Peck Szee Tan, Hae-Young Park, Ralf B. Schittenhelm, Nicole Michael, Marnie Blewitt, Irina Caminschi, Ken Shortman, Anthony W. Purcell, Nicos Nicola, Jian-Guo Zhang, Mireille H. Lahoud
Publikováno v:
Molecular Immunology. 150:15-16
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::47c931a33d689f64d7a85da44dc87af6
https://doi.org/10.1016/j.molimm.2022.05.058
https://doi.org/10.1016/j.molimm.2022.05.058
Autor:
Peter E. Czabotar, Peck Szee Tan, Jillian C. Danne, Marnie E. Blewitt, Rong Li, Emily Gruber, Nicos A. Nicola, Kristen J. Radford, Ken Shortman, Irina Caminschi, Cheng Huang, Anthony W. Purcell, Alex J. Fulcher, Mireille H. Lahoud, Hae-Young Park, Mark D. Wright, Georg Ramm, Antonia N. Policheni, Linda M. Wakim, Nicole Michael, Jose A Villadangos, Jian-Guo Zhang, Justine D. Mintern, Ralf B. Schittenhelm, William R. Heath, Meredith O'Keeffe, Kirsteen M. Tullett
Publikováno v:
eLife
eLife, Vol 9 (2020)
eLife, Vol 9 (2020)
The dendritic cell receptor Clec9A facilitates processing of dead cell-derived antigens for cross-presentation and the induction of effective CD8+ T cell immune responses. Here, we show that this process is regulated by E3 ubiquitin ligase RNF41 and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7dad18f93efe94b8043c45cc1ae04472
http://europepmc.org/articles/PMC7710356
http://europepmc.org/articles/PMC7710356
Autor:
Emily Gruber, Rong Li, Mireille H. Lahoud, Hae-Young Park, Peck Szee Tan, Kristen J. Radford, Linda M. Wakim, Mark D. Wright, Nicole Michael, Jillian C. Danne, Georg Ramm, Alex J. Fulcher, Nicos A. Nicola, Ken Shortman, Cheng Huang, Marnie E. Blewitt, Antonia N. Policheni, Anthony W. Purcell, Ralf B. Schittenhelm, William R. Heath, Justine D. Mintern, Meredith O'Keeffe, Kirsteen M. Tullett, Irina Caminschi, Peter E. Czabotar, Jose A Villadangos, Jian-Guo Zhang
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1f41c5a8a87cb6f25ee4ba50feeb2d99
https://doi.org/10.7554/elife.63452.sa2
https://doi.org/10.7554/elife.63452.sa2
