Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Kirstee L. Martin"'
Autor:
Paul K. Crellin, Benjamin Cao, Spencer J. Williams, Thusita Rupasinghe, Roisin O'Flaherty, Ross L. Coppel, Malcolm J. McConville, Kirstee L. Martin, Xingqiang Chen, George N. Khairallah, Julie E. Ralton, Richard A. J. O'Hair, Mark B. Richardson, Yoshiki Yamaryo-Botté
Publikováno v:
The Journal of Organic Chemistry. 78:2175-2190
Glucuronosyl diacylglycerides (GlcAGroAc2) are functionally important glycolipids and membrane anchors for cell wall lipoglycans in the Corynebacteria. Here we describe the complete synthesis of distinct acyl-isoforms of GlcAGroAc2 bearing both acyla
Autor:
Paul K. Crellin, David J. Lea-Smith, Dedreia Tull, Kirstee L. Martin, Malcolm J. McConville, James Pyke, Ross L. Coppel
Publikováno v:
Journal of Biological Chemistry. 283:6773-6782
The cell walls of the Corynebacterineae, which includes the important human pathogen Mycobacterium tuberculosis, contain two major lipopolysaccharides, lipoarabinomannan (LAM) and lipomannan (LM). LAM is assembled on a subpool of phosphatidylinositol
Autor:
Alan R. Prescott, M. Lucia S. Güther, Magnus S. Alphey, Michael A. J. Ferguson, Daniel C. Turnock, Kirstee L. Martin, Matthew J. Stokes
Publikováno v:
The Journal of Biological Chemistry
A gene encoding Trypanosoma brucei UDP-N-acetylglucosamine pyrophosphorylase was identified, and the recombinant protein was shown to have enzymatic activity. The parasite enzyme is unusual in having a strict substrate specificity for N-acetylglucosa
Autor:
Terry K. Smith, Kirstee L. Martin
Publikováno v:
Molecular Microbiology. 61:89-105
Summary In bloodstream-form Trypanosoma brucei (the causative agent of African sleeping sickness) the glycosylphosphatidylinositol (GPI) anchor biosynthetic pathway has been validated genetically and chemically as a drug target. The conundrum that GP
Publikováno v:
Enzyme and Microbial Technology. 38:351-357
Two extracellular β-1,6-glucanases were isolated, purified and characterized from culture filtrates of the fungus Acremonium OXF C13 grown with pustulan as sole carbon source. Both behaved as endo-acting enzymes and shared other biochemical characte
The three β-1,3-glucanases from Acremonium blochii strain C59 appear to be encoded by separate genes
Publikováno v:
Mycological Research. 110:66-74
Three exocellular beta-1,3-glucanases from Acremonium blochii strain C59, BGN3.2, BGN3.3 and BGN3.4, were purified. Two, BGN3.2 and BGN3.4 appeared to act as exo-enzymes against laminarin from Laminaria digitata, while BGN3.3 displayed an endo-mode o
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 34
Background: CSL112 was designed as an infusible formulation of human apoA-I to rapidly remove plaque cholesterol and reduce risk after an ACS. Following the initial efflux of unesterified cholesterol from cells, the second step of reverse cholesterol
Autor:
Jiezhong Chen, Jayus, Robert J. Seviour, Simon Jon McIlroy, Barbara M. McDougall, Kirstee L. Martin
Publikováno v:
FEMS microbiology reviews. 31(2)
Many fungi produce exocellular beta-glucan-degrading enzymes, the beta-glucanases including the noncellulolytic beta-(1,3)- and beta-(1,6)-glucanases, degrading beta-(1,3)- and beta-(1,6)-glucans. An ability to purify several exocellular beta-glucana
Autor:
Terry K. Smith, Kirstee L. Martin
PI (phosphatidylinositol) is a ubiquitous eukaryotic phospholipid which serves as a precursor for messenger molecules and GPI (glycosylphosphatidylinositol) anchors. PI is synthesized either de novo or by head group exchange by a PIS (PI synthase). T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::830dac045e55c8da4fade77ec24f0dbb
https://europepmc.org/articles/PMC1462709/
https://europepmc.org/articles/PMC1462709/
Autor:
Robert J. Seviour, Antony Bacic, Frank Schmid, Robert T. C. Brownlee, Barbara M. McDougall, Kirstee L. Martin, Eugene. Chai, Bruce A. Stone
Publikováno v:
Carbohydrate research. 331(2)
The extracellular fungal polysaccharide, epiglucan, synthesised by Epicoccum nigrum is a side-chain/branched (1 --> 3;1 --> 6)-D-beta-glucan. Methylation analysis, 13C DEPT NMR and specific enzymic digestion data show slight variation in branching fr