Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Kirsi Saukkonen"'
Autor:
Heidi Loponen, Juha Mehtälä, Tero Ylisaukko‐oja, Oscar Brück, Kimmo Porkka, Perttu Koskenvesa, Kirsi Saukkonen, Juha Lievonen
Publikováno v:
eJHaem, Vol 4, Iss 4, Pp 1019-1029 (2023)
Abstract In this single‐center study, we aimed to describe the characteristics, treatment patterns, and outcomes of patients with multiple myeloma (MM) following treatment with bortezomib, carfilzomib, daratumumab, ixazomib, lenalidomide or pomalid
Externí odkaz:
https://doaj.org/article/b282a0eb85e946819a19db45b18368ef
Autor:
Kirsi Saukkonen, Akseli Hemminki
Publikováno v:
Expert Opinion on Biological Therapy. 4:683-696
Adenoviral cancer gene therapy approaches have resulted in promising recent results. Following only a decade of intense development, some of the crucial obstacles are now being overcome. Insufficient transduction has been the main limitation of earli
Autor:
Kirsi Saukkonen, Caj Haglund, Johanna Rintahaka, Bastiaan P. van Rees, J. Jan B. van Lanschot, Anna Sivula, Ari Ristimäki, Marie Christine Rio, G. Johan A. Offerhaus, Christianne J. Buskens
Publikováno v:
APMIS. 111:915-925
Epidemiological studies have shown that the use of nonsteroid anti-inflammatory drugs (NSAIDs) is associated with reduced risk of gastric cancer. The best-known target of NSAIDs is the cyclooxygenase (Cox) enzyme. Two Cox genes have been cloned, of w
Autor:
Guido N. J. Tytgat, Paul Drillenburg, Kirsi Saukkonen, Bastiaan P. van Rees, Ari Ristimäki, Wojciech Polkowski, G. Johan A. Offerhaus
Publikováno v:
The Journal of Pathology. 196:171-179
The prolonged use of non-steroidal anti-inflammatory drugs (NSAIDs) has been associated with a reduced risk of gastric cancer. The best-known target of these drugs is cyclooxygenase (COX); the COX-2 isoform is frequently up-regulated in gastric adeno
Autor:
Samuel D. Wright, Stanley Falkow, Douglas T. Golenbock, Kirsi Saukkonen, David A. Relman, Elaine Tuomanen
Publikováno v:
Cell. 61:1375-1382
During the course of whooping cough, Bordetella pertussis interacts with alveolar macrophages and other leukocytes on the respiratory epithelium. We report here mechanisms by which these bacteria adhere to human macrophages in vitro. Whole bacteria a
Autor:
Tiina-Liisa Erkinheimo, Anna Sivula, Johanna Rintahaka, Leena Pohjola, Ari Ristimäki, J. Jan B. van Lanschot, Kirsi Saukkonen, G. Johan A. Offerhaus, Christianne J. Buskens, Bastiaan P. van Rees, Caj Haglund
Publikováno v:
COX-2 Inhibitors ISBN: 9783034896078
Multiple epidemiological studies indicate that the use of aspirin and other NSAIDs are associated with reduced risk of malignancies especially in the digestive tract. In addition, another NSAID sulindac causes regression of colorectal adenomatous pol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f8980a3afa21bf662d0adb0a3dbd07d5
https://doi.org/10.1007/978-3-0348-7879-1_11
https://doi.org/10.1007/978-3-0348-7879-1_11
Publikováno v:
Cancer research. 63(12)
Expression of cyclooxygenase-2 (Cox-2) is elevated in gastric adenocarcinomas and precursor lesions leading to this disease. Mice deficient for trefoil factor 1 (TFF1) develop a pyloric adenoma with full penetrance. Because inhibition of Cox-2 suppre
Autor:
Bastiaan P, van Rees, Kirsi, Saukkonen, Ari, Ristimäki, Wojciech, Polkowski, Guido N J, Tytgat, Paul, Drillenburg, G Johan A, Offerhaus
Publikováno v:
The Journal of pathology. 196(2)
The prolonged use of non-steroidal anti-inflammatory drugs (NSAIDs) has been associated with a reduced risk of gastric cancer. The best-known target of these drugs is cyclooxygenase (COX); the COX-2 isoform is frequently up-regulated in gastric adeno
Publikováno v:
The Journal of clinical endocrinology and metabolism. 86(4)
Prostaglandins (PGs) have been implicated in regulation of ovarian function. We have previously shown that the expression of cyclooxygenase-2 and the receptor for PGF(2 alpha) are expressed in periovulatory human granulosa cells and upregulated by go
Autor:
Ari Ristimäki, Stig Nordling, Kristina Hotakainen, Kirsi Saukkonen, Outi Nieminen, Caj Haglund
Publikováno v:
The American journal of pathology. 158(3)
Recent studies suggest that expression of cyclooxygenase-2 (Cox-2) is elevated in transitional cell carcinoma (TCC) of the urinary bladder and that inhibition of Cox-2 activity suppresses bladder cancer in experimental animal models. We have investig