Výsledky vyhledávání - "Kirsi M Kuusisto"

Akademický článek

copy number variation analysis in familial BRCA1/2-negative Finnish breast and ovarian cancer.

Autor: Kirsi M Kuusisto, Oyediran Akinrinade, Mauno Vihinen, Minna Kankuri-Tammilehto, Satu-Leena Laasanen, Johanna Schleutker

Publikováno v: PLoS ONE, Vol 8, Iss 8, p e71802 (2013)

BackgroundInherited factors predisposing individuals to breast and ovarian cancer are largely unidentified in a majority of families with hereditary breast and ovarian cancer (HBOC). We aimed to identify germline copy number variations (CNVs) contrib

Externí odkaz: https://doaj.org/article/4842ef037dbe436a9fc91a1bc1c7d1af

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Screening for BRCA1, BRCA2, CHEK2, PALB2, BRIP1, RAD50, and CDH1 mutations in high-risk Finnish BRCA1/2-founder mutation-negative breast and/or ovarian cancer individuals

Autor: Johanna Schleutker, Satu-Leena Sallinen, Aleksandra Bebel, Mauno Vihinen, Kirsi M. Kuusisto

Publikováno v: Breast Cancer Research : BCR

Introduction Two major high-penetrance breast cancer genes, BRCA1 and BRCA2, are responsible for approximately 20% of hereditary breast cancer (HBC) cases in Finland. Additionally, rare mutations in several other genes that interact with BRCA1 and BR

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::061bc66b650d37e6c4396ae2e20bd511
https://pubmed.ncbi.nlm.nih.gov/21356067

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Abstract LB-284: Exome sequencing of high-risk Finnish hereditary breast and breast-ovarian cancer families

Autor: Tommi Rantapero, Matti Nykter, Johanna Schleutker, Kirsi M. Kuusisto, Minna Kankuri-Tammilehto, Satu-Leena Laasanen

Publikováno v: Cancer Research. 75:LB-284

Background: Breast cancer has a well-established genetic component. However, genetic predisposition factors remain mostly unresolved in high-risk hereditary breast cancer families that do not carry mutations in two major susceptibility genes, BRCA1 a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::57022a15b8fc3aead6b3b001ef4324af
https://doi.org/10.1158/1538-7445.am2015-lb-284

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Copy Number Variation Analysis in Familial BRCA1/2-Negative Finnish Breast and Ovarian Cancer

Autor: Minna Kankuri-Tammilehto, Oyediran Akinrinade, Johanna Schleutker, Mauno Vihinen, Satu-Leena Laasanen, Kirsi M. Kuusisto

Publikováno v: PLoS ONE
PLoS ONE; 8(8), no e71802 (2013)
PLoS ONE, Vol 8, Iss 8, p e71802 (2013)

Background Inherited factors predisposing individuals to breast and ovarian cancer are largely unidentified in a majority of families with hereditary breast and ovarian cancer (HBOC). We aimed to identify germline copy number variations (CNVs) contri

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::365d75617c301d36528df799ad0476d1
https://doi.org/10.1371/journal.pone.0071802

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