Antigen specificity of clonally-enriched CD8+ T cells in multiple sclerosis.

Autor: Mittl K, Hayashi F, Dandekar R, Schubert RD, Gerdts J, Oshiro L, Loudermilk R, Greenfield A, Augusto DG, Ramesh A, Tran E, Koshal K, Kizer K, Dreux J, Cagalingan A, Schustek F, Flood L, Moore T, Kirkemo LL, Cooper T, Harms M, Gomez R, Sibener L, Cree BAC, Hauser SL, Hollenbach JA, Gee M, Wilson MR, Zamvil SS, Sabatino JJ

Publikováno v: BioRxiv : the preprint server for biology [bioRxiv] 2024 Oct 17. Date of Electronic Publication: 2024 Oct 17.

PVRL2 Suppresses Antitumor Immunity through PVRIG- and TIGIT-independent Pathways.

Autor: Yang J; Department of Urology, University of California San Francisco, San Francisco, California., Wang L; Department of Urology, University of California San Francisco, San Francisco, California., Byrnes JR; Department of Pharmaceutical Chemistry, University of California San Francisco, San Francisco, California., Kirkemo LL; Department of Pharmaceutical Chemistry, University of California San Francisco, San Francisco, California., Driks H; Department of Urology, University of California San Francisco, San Francisco, California., Belair CD; Department of Urology, University of California San Francisco, San Francisco, California., Aguilar OA; Department of Microbiology and Immunology, University of California, San Francisco, and Parker Institute for Cancer Immunotherapy, San Francisco, California., Lanier LL; Department of Microbiology and Immunology, University of California, San Francisco, and Parker Institute for Cancer Immunotherapy, San Francisco, California., Wells JA; Department of Pharmaceutical Chemistry, University of California San Francisco, San Francisco, California., Fong L; Division of Hematology/Oncology, Department of Medicine, University of California, San Francisco, San Francisco, California., Blelloch R; Department of Urology, University of California San Francisco, San Francisco, California.

Publikováno v: Cancer immunology research [Cancer Immunol Res] 2024 May 02; Vol. 12 (5), pp. 575-591.

Photoproximity Labeling from Single Catalyst Sites Allows Calibration and Increased Resolution for Carbene Labeling of Protein Partners In Vitro and on Cells.

Autor: Bartholow TG; Department of Pharmaceutical Chemistry, University of California San Francisco, San Francisco, California 94158, United States., Burroughs PWW; Department of Pharmaceutical Chemistry, University of California San Francisco, San Francisco, California 94158, United States., Elledge SK; Department of Pharmaceutical Chemistry, University of California San Francisco, San Francisco, California 94158, United States., Byrnes JR; Department of Pharmaceutical Chemistry, University of California San Francisco, San Francisco, California 94158, United States., Kirkemo LL; Department of Pharmaceutical Chemistry, University of California San Francisco, San Francisco, California 94158, United States., Garda V; Department of Pharmaceutical Chemistry, University of California San Francisco, San Francisco, California 94158, United States., Leung KK; Department of Pharmaceutical Chemistry, University of California San Francisco, San Francisco, California 94158, United States., Wells JA; Department of Pharmaceutical Chemistry, University of California San Francisco, San Francisco, California 94158, United States.; Department of Cellular & Molecular Pharmacology, University of California San Francisco, San Francisco, California 94158, United States.

Publikováno v: ACS central science [ACS Cent Sci] 2023 Dec 26; Vol. 10 (1), pp. 199-208. Date of Electronic Publication: 2023 Dec 26 (Print Publication: 2024).

Site-specific proximity labeling at single residue resolution for identification of protein partners in vitro and on cells.

Autor: Bartholow TG, Burroughs P, Elledge SK, Byrnes JR, Kirkemo LL, Garda V, Leung KK, Wells JA

Publikováno v: BioRxiv : the preprint server for biology [bioRxiv] 2023 Jul 27. Date of Electronic Publication: 2023 Jul 27.

Discovery Proteomics Analysis Determines That Driver Oncogenes Suppress Antiviral Defense Pathways Through Reduction in Interferon-β Autocrine Stimulation.

Autor: Solomon PE; Department of Pharmaceutical Chemistry, University of California, San Francisco, San Francisco, California, USA., Kirkemo LL; Department of Pharmaceutical Chemistry, University of California, San Francisco, San Francisco, California, USA., Wilson GM; Department of Chemistry, University of Wisconsin-Madison, Madison, Wisconsin, USA; Department of Biomolecular Chemistry, University of Wisconsin-Madison, Madison, Wisconsin, USA., Leung KK; Department of Pharmaceutical Chemistry, University of California, San Francisco, San Francisco, California, USA., Almond MH; Division of Infectious Diseases, Department of Medicine, UCSF Medical Center, University of California, San Francisco, California, USA., Sayles LC; Department of Pediatrics, University of California San Francisco, California, USA., Sweet-Cordero EA; Department of Pediatrics, University of California San Francisco, California, USA., Rosenberg OS; Division of Infectious Diseases, Department of Medicine, UCSF Medical Center, University of California, San Francisco, California, USA; Department of Biophysics and Biochemistry, Chan Zuckerberg Biohub, San Francisco, California, USA., Coon JJ; Department of Chemistry, University of Wisconsin-Madison, Madison, Wisconsin, USA; Department of Biomolecular Chemistry, University of Wisconsin-Madison, Madison, Wisconsin, USA; National Center for Quantitative Biology of Complex Systems, University of Wisconsin-Madison, Madison, Wisconsin, USA., Wells JA; Department of Pharmaceutical Chemistry, University of California, San Francisco, San Francisco, California, USA; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, California, USA. Electronic address: jim.wells@ucsf.edu.

Publikováno v: Molecular & cellular proteomics : MCP [Mol Cell Proteomics] 2022 Jul; Vol. 21 (7), pp. 100247. Date of Electronic Publication: 2022 May 18.