Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Kirk W. Foster"'
Publikováno v:
Surgery Open Science, Vol 16, Iss , Pp 127-133 (2023)
Background: Patients suffering from severe acute respiratory distress syndrome (ARDS) face limited therapeutic options and alarmingly high mortality rates. Refractory hypoxemia, a hallmark of ARDS, often necessitates invasive and high-risk treatments
Externí odkaz:
https://doaj.org/article/b7b3c746b7b34ee8b2aaff871a5cdf29
Publikováno v:
BMC Infectious Diseases, Vol 23, Iss 1, Pp 1-4 (2023)
Abstract Background Disseminated Clostridium septicum infection is an uncommon complication associated with malignancies, particular colonic adenocarcinoma. The organism appears to preferentially colonize large masses in rare individuals and subseque
Externí odkaz:
https://doaj.org/article/88df5f380da849b2a04aa489ef650d2e
Autor:
Rouhin Sen, Kathleen Borghoff, Kirk W. Foster, Stanley J. Radio, Alan Erickson, Michelene Hearth-Holmes
Publikováno v:
Case Reports in Rheumatology, Vol 2022 (2022)
Background. Hydroxychloroquine is an effective and widely used treatment in multiple autoimmune connective tissue diseases that gained a lot of publicity in the coronavirus disease 2019 (COVID-19) pandemic. Our case reports are unique in that they ex
Externí odkaz:
https://doaj.org/article/d3224f7b71d94db9ba7ac7c86d08bdb8
Autor:
Chunyi Zhou, Fatema Bhinderwala, McKenzie K Lehman, Vinai C Thomas, Sujata S Chaudhari, Kelsey J Yamada, Kirk W Foster, Robert Powers, Tammy Kielian, Paul D Fey
Publikováno v:
PLoS Pathogens, Vol 15, Iss 1, p e1007538 (2019)
Staphylococcus aureus causes acute and chronic infections resulting in significant morbidity. Urease, an enzyme that generates NH3 and CO2 from urea, is key to pH homeostasis in bacterial pathogens under acidic stress and nitrogen limitation. However
Externí odkaz:
https://doaj.org/article/b6a142c54e844649a86a7814448d4144
Autor:
Hee-Seong Jang, Ao Yu, Chuhan Zhang, Yu Hang, Yi Chen, Kirk W. Foster, Ling Ding, Jing Li, David Oupický, Chinmay M. Jogdeo, Babu J. Padanilam, Weimin Tang, Fei Yu
Publikováno v:
J Control Release
Acute kidney injury (AKI) is characterized by a sudden loss of renal function and is associated with high morbidity and mortality. Tumor suppressor p53 and chemokine receptor CXCR4 were both implicated in the AKI pathology. Here, we report on the dev
Autor:
Weimin Tang, Sudipta Panja, Chinmay M. Jogdeo, Siyuan Tang, Ling Ding, Ao Yu, Kirk W. Foster, Del L. Dsouza, Yashpal S. Chhonker, Heather Jensen-Smith, Hee-Seong Jang, Erika I. Boesen, Daryl J. Murry, Babu Padanilam, David Oupický
Publikováno v:
Biomaterials
Acute kidney injury (AKI) is characterized by a sudden decrease in renal function and impacts growing number of people worldwide. RNA interference (RNAi) showed potential to treat diseases with no or limited conventional therapies, including AKI. Sui
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ccb7b9bd34940c6558e24b72364011c2
https://europepmc.org/articles/PMC9133205/
https://europepmc.org/articles/PMC9133205/
Autor:
Zhifeng Zhao, Haochen Jiang, Xiaoke Xu, Zhenshan Jia, Rongguo Ren, Kirk W. Foster, Xin Wei, Ningrong Chen, Steven R. Goldring, Mary K. Crow, Dong Wang
Publikováno v:
Nanomedicine : nanotechnology, biology, and medicine. 44
Due to their potent immunosuppressive and anti-inflammatory effects, glucocorticoids (GCs) are the most widely used medications in treating lupus nephritis (LN). Long-term use of GCs, however, is associated with numerous off-target adverse effects. T
Autor:
Babu J. Padanilam, Kirk W. Foster, David Oupicky, Fernando A. Ferrer, Hee-Seong Jang, Mi Ra Noh, Siddesh Southekal, Woo Yang Kim, Eui Man Jung, Chittibabu Guda
Publikováno v:
Kidney Int
Regardless of the etiology, acute kidney injury involves aspects of mitochondrial dysfunction and ATP depletion. Fatty acid oxidation is the preferred energy source of the kidney and is inhibited during acute kidney injury. A pivotal role for the mit
Autor:
Ningrong Chen, Xiaoke Xu, Xin Wei, Zhenshan Jia, Kirk W. Foster, Haochen Jiang, Zhifeng Zhao, Mary K. Crow, Steven R. Goldring, Dong Wang
Publikováno v:
Mol Pharm
Glucocorticoids (GCs) are widely used in the clinical management of lupus nephritis (LN). Their long-term use, however, is associated with the risk of significant systemic side effects. We have developed a poly(ethylene glycol) (PEG)-based dexamethas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e31e9298390a105bcdb2e1b1cc087ea
https://europepmc.org/articles/PMC9364269/
https://europepmc.org/articles/PMC9364269/
Autor:
R Brian Stevens, Kirk W Foster, Clifford D Miles, Andre C Kalil, Diana F Florescu, John P Sandoz, Theodore H Rigley, Tamer Malik, Lucile E Wrenshall
Publikováno v:
PLoS ONE, Vol 10, Iss 10, p e0139247 (2015)
The two most significant impediments to renal allograft survival are rejection and the direct nephrotoxicity of the immunosuppressant drugs required to prevent it. Calcineurin inhibitors (CNI), a mainstay of most immunosuppression regimens, are parti
Externí odkaz:
https://doaj.org/article/a27c18914590473cb4f3b3e9342bf8b8