Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Kirk Volker"'
Autor:
William E. Fogler, Kirk Volker, Morihiro Watanabe, Jon M. Wigginton, Philip Roessler, Michael J. Brunda, John R. Ortaldo, Robert H. Wiltrout
Publikováno v:
The Journal of Immunology. 161:6014-6021
NK cells have been shown to be important antitumor or antiviral effector cells in the liver. In the present study we have examined the factors that regulate the initial recruitment and subsequent fate of hepatic NK and T cells in mice treated with IL
Autor:
Sally E. Spence, Susanna M. Rybak, Stanislaw M. Mikulski, William E. Fogler, John W. Pearson, Dianne L. Newton, Kirk Volker, Charles W. Riggs, Wojciech Ardelt, Dan L. Longo, Hsiang-Fu Kung
Publikováno v:
JNCI: Journal of the National Cancer Institute. 88:747-753
Background : Onconase, a protein isolated from oocytes and early embryos of the frog Rana pipiens, shares extensive homology with bovine pancreatic ribonuclease (RNase A) and possesses similar enzyme activity. Onconase is cytotoxic toward cancer cell
Autor:
Charles W. Riggs, Dan L. Longo, William E. Fogler, John W. Pearson, Hirotsugu Watabe, Kirk Volker, Robert H. Wiltrout, Keiko Ariyoshi
Publikováno v:
JNCI Journal of the National Cancer Institute. 87:94-103
BACKGROUND The anti-P-glycoprotein monoclonal antibody MRK-16 mediates the reversal of multidrug resistance. Recombinant human interferon alfa (rHuIFN alpha) enhances the cytotoxic activity of diverse chemotherapeutics and may modulate multidrug resi
Autor:
Kirk Volker, Noriko Usui, Sarah Goldenberg, Charles W. Riggs, Dan L. Longo, William E. Fogler, Michael M. Gottesman, Ira Pastan, Takashi Tsuruo, Eileen Gruys, Robert H. Wiltrout, John W. Pearson, Kristin L. Komschlies
Publikováno v:
Journal of the National Cancer Institute. 83(19)
One strategy to overcome multidrug resistance in neoplasia is to inhibit the gp170 glycoprotein (relative molecular mass, 170,000) that functions as a plasma membrane, energy-dependent, drug-efflux pump. The human colon cancer cell line HT-29, which