Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Kirk T. Kawagoe"'
Publikováno v:
Journal of Neuroscience Methods. 112:119-133
Quantifying mechanisms underlying extracellular signaling by the neurotransmitter dopamine (DA) is a difficult task, particularly in the complex extracellular microenvironment of the intact brain. In this study, two methods for evaluating release and
Publikováno v:
Analytical Chemistry. 69:1662-1668
A digital approach for the collection and analysis of electrochemical frequency domain spectra is presented for the oxidation of carbohydrates at a copper electrode using a continuous, large-amplitude sine wave as an excitation waveform. The backgrou
Autor:
Kirk T. Kawagoe, R. Mark Wightman
Publikováno v:
Talanta. 41:865-874
Constant potential amperometry with Nafion-coated carbon-fiber electrodes has been evaluated as a technique for in vivo detection of the neurotransmitter dopamine. The results of this technique have been compared to results obtained with fast-scan cy
Publikováno v:
Journal of Electroanalytical Chemistry. 359:193-207
Cyclic voltammetry has been used to examine pH-dependent processes in aqueous solution at carbon-fiber electrodes with scan rates above 100 V s−1. Specifically, the reduction of p-benzoquinone and the oxidation of dopamine have been investigated. T
Autor:
R. Mark Wightman, Edward L. Ciolkowski, Donna J. Wiedemann, Robert T. Kennedy, Kirk T. Kawagoe
Publikováno v:
Analytical Chemistry. 63:2965-2970
Cyclic voltammetry of Nafion-coated, carbon-fiber electrodes is used to detect trace concentrations of dopamine, both in a flow injection apparatus and in the brain of an anaesthetized rat. To improve signal-to-noise ratios, the sources of noise duri
Publikováno v:
Analytical Chemistry. 63:1589-1594
Voltammetric electrodes with micrometer dimensions have been fabricated from carbon fibers etched to a conical shape and insulated with poly(oxyphenylene) following literature procedures. The resultant electrode has a tip radius in the micron range.
Publikováno v:
Journal of neuroscience methods. 52(1)
Fast-scan cyclic voltammetry (FSCV) at carbon-fiber microelectrodes was used to investigate catecholamine release and uptake induced by local electrical stimulation of rat brain slices containing the basolateral amygdaloid nucleus. The amygdala conta
Publikováno v:
Journal of neuroscience methods. 48(3)
In vivo voltammetry is approaching the end of its second decade as a technique to explore extracellular concentrations in the brain. The issues of selectivity and sensitivity, which caused considerable discussion and confusion in the early 1980s, are
Autor:
Christian Amatore, Christine Lefrou, Jeffrey A. Jankowski, Kirk T. Kawagoe, T.J. Schroeder, R. Mark Wightman
Publikováno v:
Analytical chemistry. 64(24)
Secretion of catecholamines is observed as a series of current spikes when measured at the surface of a bovine adrenal medullary cell in culture with a carbon-fiber microelectrode operated in the amperometric mode. Prior work has shown that these spi
Publikováno v:
Neuroscience. 51(1)
Synaptic overflow of dopamine in the striatum has been investigated during electrical stimulation of the medial forebrain bundle in anesthetized rats. Dopamine has been detected with Nafion-coated, carbon-fiber electrodes used with fast-scan voltamme